Associated Faculty

An asterisk (*) denotes faculty who participate in the Anti-Cancer Drug Development Training Program.

*L. Mario Amzel, Ph.D., Professor
3-D structure of proteins: immunoglobulins and other binding proteins; ATP synthase; monoxygenases and dioxygenases quinone reductase.

Marc M. Greenberg, Ph.D., Professor
Chemical and biochemical approaches to the study of DNA damage and repair, and their applications.

*Carol Greider, Ph.D., Professor
Telomerase and telomere length regulation.

Richard L. Huganir, Ph.D., Professor
Molecular mechanisms in the regulation of synaptic plasticity.

*John T. Isaacs, Ph.D., Professor
Anti-cancer drug development; Normal and malignant stem cell biology.

*William B. Isaacs, Ph.D., Professor
Understanding the molecular genetic events responsible for initiation and progression of prostate cancer, with particular interest in inherited susceptibility to prostate cancer.

*Elizabeth M. Jaffee, M.D., Professor
Analysis of antitumor immune responses against human tumors; identification of the targets of tumor-specific cytotoxic T cells.

*Kenneth W. Kinzler, Ph.D., Professor
Molecular genetics of cancer, translational cancer research.

*Mark Levis, M.D., Ph.D., Associate Professor
Targeting the FLT3 signaling pathway as a treatment for acute leukemia.

*Paula M. Pitha-Rowe, Ph.D., Professor
Effects of viral infection on expression of cellular (cytokines and chemokines and their receptors) and viral (HIV-1, HHV-8) genes; targeted antiviral and anticellular therapy (gene transfer, ribozymes); breast cancer: role of c-erbB-2.

*Stuart C. Ray, M.D., Professor
Computational immunovirology of chronic viral hepatitis.

*Charles M. Rudin, M.D., Ph.D., Professor
Molecular mechanisms of apoptosis, roles of apoptosis in carcinogenesis and therapeutic resistance, novel therapeutic development in animal models of cancer.

*Saraswati Sukumar, Ph.D., Professor
Molecular alterations in breast cancer.

*Craig A. Townsend, Ph.D., Professor
Organic and bioorganic chemistry: biosynthesis of natural products and biomimetic synthesis; elucidation of protein function; molecular biology of secondary metabolism and engineering of biosynthetic systems to practical ends; study of the role and inhibition of fatty acid synthesis in human cancer, tuberculosis, and obesity.

*Srinivasan Yegnasubramanian, M.D., Ph.D., Assistant Professor
Understanding and exploiting alterations in the cancer genome and epigenome for development of biomarkers and therapeutics.

*Bert Vogelstein, M.D., Professor
Molecular genetics of human cancer.