Indications and Contraindications for Pediatric Transplantation

Protocols for Patient Selection, Including Indications and Contraindications for Pediatric Liver Transplantation

We welcome a call from physicians and medical professionals who are interested in discussing pediatric transplantation or potential indications or contraindications for a specific patient.  If you are a medical professional calling from a physician's office and would like to reach a Hopkins transplant physician, please feel free to call us using any of the numbers listed below:

Pediatric Liver Transplantation (main office) 410-955-8769
or Hopkins Access Line for Physicians (24 hours, 7 days a week) 410-955-9444 or 1-800-765-JHHS

The Pediatric Liver Transplant Program offers a multidisciplinary approach to the evaluation and selection of patients for its transplantation program.  Physicians, transplant nurse coordinators, social workers, counselors and other professionals from numerous disciplines at the Johns Hopkins Hospital assist in the evaluation and selection process. 

Patient Selection Criteria:

Any condition that results in end-stage liver disease, including, but not limited to

• Biliary Atresia
• Alagille’s Syndrome
• Alpha-1-Antirypsin Deficiency
• Chronic Active Hepatitis
• Acute Viral Hepatitis
• Autoimmune Hepatitis
• Fulminant Viral Hepatitis
• Toxic Liver Failure
• Tyrosinemia
• Glycogen Storage Diseases
• Congenital Hepatic Fibrosis
• Byler’s Syndrome
• Wilson’s Disease
• Hepatoblastoma
  
  

Absolute contraindications for children include, but may not be limited to:

• Advanced cardiopulmonary disease
• Active malignancy with metastises
• Severe local or systemic infection
• Untreatable psychiatric illness

Relative Contraindications for children include, but may not be limited to:

• Lack of family or social support
• Evidence of significant non-adherence

Other links in Pediatric Transplant site:

Transplant Team
Information for Healthcare Professionals
Referring Physician Checklist