Clinical Activities
Liver Clinic
Friday 9 – 12 noon, David M. Rubenstein Clinic – 200 South Wolfe Street
Procedures
We offer a large variety of procedures necessary for diagnosis and treatment of childhood liver diseases including percutaneous and transjugular liver biopsies, variceal sclerotherapy and banding, and upper and lower endoscopy
Patient care
We care for over 1000 children with a large variety of acute and chronic liver diseases (please see our Pediatric Liver Center Database piechart below)

Typical Clinical Challenges
The jaundiced newborn
• Giant cell hepatitis
• Congenital infection
• Metabolic liver disease
• Choledochal cyst
• Biliary atresiaThe child with elevated liver enzymes
• Viral hepatitis (A,B,C,D,E,G,etc.)
• Autoimmune hepatitis
• Metabolic liver disease
• Nonalcoholic fatty liver disease
The jaundiced child
• Sclerosing cholangitis
• Gallstones
• Neoplasms
• Biliary tract anomaliesThe child with liver failure
• Fulminant
• Acute
• Chronic
Medical Experitise
Pediatric hepatology
• Two decades of experience
• Percutaneous liver biopsy
• Gastrointestinal endoscopy
• Nutrition Support Team
• Antiviral, immunosuppressant
and metabolic therapies
Pediatric radiology
• Doppler ultrasound
• Computed axial tomography
• Magnetic resonance imaging
• Nuclear medicine
• Transjugular liver biopsy
• Intrahepatic portosystemic shuntsTherapeutic endoscopy
• Endoscopic retrograde cholangiopancreatography
• Endoscopic ultrasound
• Dilatation of biliary strictures
• State of the art diagnostic laboratoriesPathology
• Routine and special staining
• Enzymes
• Electron microscopy
• In situ DNA studies Virology
• Rapid diagnosis of viral hepatitis
Metabolism
• Analysis of amino acids, organic acids, fatty acids and sterols
Surgical Solutions
Biliary tract procedures
• Choledochal cyst resection
• Hepatic portoenterostomy for biliary atresia
• Laparoscopic cholecystectomyPartial hepatectomy
• Benign cysts and tumors
• Primary hepatic malignancies
• Liver metastasesLiver transplantation
• Almost 2 decades of success
• Program began in 1987
• 5th largest center in the country for living related liver transplantation
• Transplant Center of Excellence
• More than 150 children transplanted
• High survival rates
• Innovative approaches including:living related donors, reduced size transplants, split liver transplants, liver/kidney transplants



