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Department of Otolaryngology-Head and Neck Surgery
 
 
 
 
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A monoclonal antibody labels type II neurons of the spiral ganglion

Abstract:

Berglund, A.M., and D.K. Ryugo (1986)
A monoclonal antibody labels type II neurons of the spiral ganglion. Brain Research 383:327-332.

Tissue from mature rat and cat cochleas was stained with basic dyes in order to distinguish between the cell bodies of type I and II spiral ganglion neurons. This same tissue was then stained with protargol, or processed immunocytochemically using a monoclonal neurofilament antibody, RT-97. Type II neurons were intensely stained, whereas type I neurons were not. We conclude that type II neurons can be clearly distinguished by their abundant neurofilament content.

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