Obsessive Compulsive Disorder at Johns Hopkins

Our Publication

    Cullen C, Samuels JF, Pinto A, et al Demographic and clinical characteristics associated with treatment status in family members with obsessive-compulsive disorder. Depression and Anxiety (in press).

    Samuels J*, Shugart YY* (joint first authors), Grados M., Willour V., Bienvenu O., Greenberg B., Knowles J., McCracken J., Rauch S., Murphy D., Wang Y., Pinto A., Fyer A., Piacentini J., Pauls D., Cullen B., Rasmussen S., Hoehn-Saric R., Valle D., Liang K., Riddle M., and Nestadt G. Significant linkage to compulsive hoarding on chromosome 14 in families with obsessive compulsive disorder. American Journal of Psychiatry (in press).

    Wellen D., Samuels J., Bienvenu O.J., Grados M., Cullen B., Riddle M., Liang K.Y., and Nestadt G. The utility of the Leyton Obsessional Inventory in distinguishing OCD and OCPD. Depression and Anxiety (in press).

    Hasler G., Pinto A., Greenberg B.D., Samuels J., Fyer A.J., Pauls D., Knowles J.A., McCracken J.T., Piacentini J., Riddle M.A., Rauch S.L., Rasmussen S.A., Willour V.L., Grados M.A., Cullen B., Bienvenu O.J., Shugart Y.Y., Liang K.Y., Hoehn-Saric R., Wang Y., Ronquillo J., Nestadt G., and Murphy D.L. Familiality of factor analysis-derived YBOCS dimensions in OCD affected sibling pairs from the OCD Collaborative Genetics Study. Biological Psychiatry 2007; 61(5):617-625.

    Cullen B, Brown CH, Riddle MA, Grados M, Bienvenu OJ, Willour VL, Hoehn-Saric R, Shugart YY, Liang K-Y, Samuels J, Nestadt G Factor analysis of the Yale-Brown Obsessive Compulsive Scale in a family study of obsessive compulsive disorder. Depression and Anxiety 2007; 24(2):130-138.

    Samuels J.F., Bienvenu O.J., III, Pinto A., Fyer A.J., McCracken J.T., Rauch S.L., Murphy D.L., Grados M.A., Greenberg B.D., Knowles J.A., Piacentini J., Cannistraro P.A., Cullen B., Riddle M.A., Rasmussen S.A., Pauls D.L., Willour V.L., Shugart Y.Y., Liang K.Y., Hoehn-Saric R., and Nestadt G. Hoarding in obsessive-compulsive disorder: results from the OCG Collaborative Genetics Study. Behaviour Research and Therapy (in press).

    Samuels JF, Riddle MA, Greenberg BD, et al The OCD Collaborative Genetics Study: methods and sample description. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 2006; 141B(3):201-207.

    Shugart YY*, Samuels J* (joint first authors), Willour V.L., Grados M.A., Greenberg B.D., Knowles J.A., McCracken J.T., Rauch S.L., Murphy D.L., Wang Y., Pinto A., Fyer A.J., Piacentini J., Pauls D.L., Cullen B., Page J., Rasmussen S.A., Bienvenu O.J., Hoehn-Saric R., Valle D., Liang K.Y., Riddle M.A., and Nestadt G.Genome-wide linkage scan for obsessive-compulsive disorder: vidence for susceptibility loci on chromosomes 3q, 7p, 15q, 6q, and 1q. Molecular Psychiatry 2006; 11:763-770.

    Hong JP, Samuels J, Bienvenu OJ, et al Clinical correlates of recurrent major depression in obsessive-compulsive disorder. Depress Anxiety 2004; 20:86-91.

    Willour V.L., Yao S.Y., Samuels J., Grados M., Cullen B., Bienvenu O.J., III, Wang Y., Liang K.Y., Valle D., Hoehn-Saric R., Riddle M., and Nestadt G. Replication study supports evidence for linkage to 9p24 in obsessive-compulsive disorder. Am J Hum Genet 2004; 75:508-513.

    Nestadt G, Addington A, Samuels JF, et al Identification of OCD-related subgroups based on comorbidity. Biological Psychiatry 2003; 53:914-920.

    Samuels J, Bienvenu III, OJ, Riddle MA, Cullen BAM, Grados MA, Liang K-Y, HoehnSaric R, and Nestadt G. Hoarding in Obsessive-Compulsive Disorder: results from a case-control study. Behaviour Research and Therapy, 2002; 40:517-528.

    Grados MA, Riddle MA, Samuels JF, Liang KY, Bienvenu OJ, Walkup JT, and Nestadt G. The association of obsessive-compulsive disorder (OCD) and tics: results from the John Hopkins OCD Family Study. Biological Psychiatry, 2001 Oct 15, 50(8):559-565.

    Nestadt G, Samuels J, Riddle MA, Bienvenu OJ, Liang KY, Grados M, and Cullen B. Obsessive Compulsive Disorder: defining the phenotype. Journal of Clinical Psychiatry, 2001, 62(suppl).

    Cullen BA, Samuels JF, Bienvenu OJ, Grados M, Hoehn-Saric R, Hahn J, Liang K-Y, Wellen D, Dees M, Riddle MA, and Nestadt G. The Relationship of Pathologic Skin Picking to Obsessive-Compulsive Disorder. J of Nervous & Mental Disease, March 2001; 189(3):193-195.

   Nestadt G, Samuels J, Riddle MA, Liang K-Y, Bienvenu OJ, Hoehn-Saric R, Grados M, and Cullen B. The Relationship between Obsessive-Compulsive Disrder and Anxiety and Affective Disorders: Results from the Johns Hopkins OCD Family Study. Psychological Medicine 2001; 31:481-487.

    Nestadt G: Commentaries: Obsessive-Compulsive Disorder: Towards a Diagnosis by Etiology. In: Maj M, Sartorius N, Okaksha A, and Zohar J (eds.): Obsessive-Compulsive Disorder. WPA Series Evidence and Experience in Psychiatry. John Wiley & Sons, Ltd, Volume 4, 2000.

    Nestadt G, Samuels J, Riddle MA, Bienvenu OJ, Liang K-Y, LaBuda M, Walkup J, Grados M, and Hoehn-Saric R. A Family Study of Obsessive-compulsive Disorder. Arch Gen Psychiatry, 2000; 57:358-363.

    Bienvenu OJ, Samuels JF, Riddle MA, Hoehn-Saric R, Liang KY, Cullen B, Grados MA, and Nestadt G. The relationship of obsessive-compulsive disorder to possible spectrum disorders: results of a family study. Biological Psychiatry 2000; 48:287-293.

    Nestadt G, Lan T, Samuels J, Riddle M, Bienvenu OJ, Liang KY, Hoehn-Saric R, Cullen B, Grados M, Beaty TH, and Shugart YY. Complex segregation analysis provides compelling evidence for a major gene underlying obsessive-compulsive disorder and for heterogeneity by sex. Am J Human Genetics 2000; 67:1611-1616.

    DeMarchi N, Morris M, Menella R, LaPia S, and Nestadt G. Association of obsessive-compulsive disorder and pathological gambling with Huntington’s disease in an Italian pedigree: possible association with Huntington’s disease mutation. Acta Psychiatr Scand 1998; 97:62-65.

    Nestadt G, Bienvenu OJ, Samuels J, and Eaton WW: Incidence of obsessive-compulsive disorders in adults. Journal of Nervous and Mental Disorders 1998; 186:401-406.

    Samuels J and Nestadt G: Epidemiology and Genetics of O.C.D. Intl J Psychiatry 1997; 9:61-71.

    Nestadt G, Samuels JF, Romanoski AJ, Folstein,MF, and McHugh PR. Prevalence and correlates of obsessions and compulsions: Results from a community survey. Acta Psychiatrica Scandinavica 1994; 89:219-224.