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Latest Advancements in Research

Researchers at Johns Hopkins are constantly advancing science through basic, translational and clinical investigations. Here are highlights of our most current findings.

Plugging In Vision's Autostabilization Feature 

a deer that is half blurry and half clear

Like a camera with an autostabilization feature, our eyes have an imperceptible reflex that prevents our vision from blurring as we move. New research describes how the wire-like projections of specialized nerve cells find their way from the retina to plug into the correct part of the brain. 

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High Blood Sugar Wreaks Havoc

mitochondria damage from diabetes

Scientists have discovered why long-term high blood sugar disrupts the normal function of mitochondria, the energy factories within cells. The discovery sheds light on a long-hidden connection and could eventually lead to new ways of preventing and treating diabetes.

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Disrupting Molecular Shield Causes Heart Damage 

a human heart glowing

New research in mice shows that so-called “oxidative stress” damages heart muscle by preventing a heart-shielding protein from doing its work. The results suggest that the right antioxidants, targeted to the heart, could help turn things around.

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Neurons Constantly Rewrite Their DNA 

Images of mouse neurons from the hippocampal region of the brain. Levels of the surface receptor GluR1, orange, are shown in unmodified neurons, left, and in those with increased levels of Tet3, right.

Johns Hopkins scientists have discovered that neurons are risk takers: They use minor “DNA surgeries” to toggle their activity levels all day, every day. Since these activity levels are important in learning, memory and brain disorders, the researchers think their finding will shed light on a range of important questions.

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Children with ADHD at Risk for Binge Eating 

girl eating hamburger

New research shows that children with attention deficit hyperactivity disorder, or ADHD, are 12 times more likely to eat impulsively than those without the disorder. The findings suggest a common biological mechanism linking the two disorders, and the potential for developing a treatment that works for both.

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