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Home > News and Publications > JHM Publications > Promise and Progress > Reprogramming Cancer Cells - The Story of Epigenetics
Promise and Progress - Cancer Patients Who Quit Smoking Live Longer
Reprogramming Cancer Cells - The Story of Epigenetics
Issue No. 1
Issue No. 1
Cancer Patients Who Quit Smoking Live Longer
Date: July 16, 2014
The Oncologist, December 2013
New evidence reveals that cigarette smoking is not just a leading cause of cancer, but it also significantly contributes to poor responses to treatment in those already suffering from the disease.
In a study of 278 patients with advanced kidney cancer, conducted at the Kimmel Cancer Center and Tel Aviv University in Israel, investigators found patients who were smokers had diminished responses to anticancer drug treatment and marked decreases in survival of seven to 15 months when compared to previous smokers and nonsmokers. The research team, led by Michael Carducci, M.D., the AEGON Professor of Prostate Cancer Research and the Associate Director for Clinical Research, found active smoking had the greatest negative affect on treatment response, cancer progression, and overall survival when measured against other factors, including obesity, high blood pressure, diabetes, and other major health risks.
Dr. Carducci and team suggest that the mechanisms of how smoking impacts treatment could be worked out, but they point to known cell damage and affects on immunologic functions as potential culprits. He recommends that clinicians advise patients with metastatic cancer to quit smoking at the start of treatment.
Articles in this Issue
- Headline Makers - Overview
- A Safer Way to Treat Pediatric Brain Cancers
- For Cervical Lesions, Tissue Exam Beats Conventional Blood Tests
- Blood Cells Transformed to Repair Damaged Retina
- Personalized Chemotherapy
- 3D Scans Show whether Treatment is Working
- Alcohol Metabolite Could Increase Cancer Risk in Some People
- Acupuncture, Real or Simulated, Eases Hot Flashes
- New Leukemia Findings
- HPV Oral Cancers and Risk of Infection for Couples
- Molecular Marker of Cancer Drug Response
- Chronic Inflammation Connected to Prostate Cancer
- Fat Versus Brain Cancer
- DNA Damaging Toxins In Food
- Cancer Patients Who Quit Smoking Live Longer
- New Immune Therapy Shows Promise Against Melanoma
- Breathe Easier and Fight Cancer
- Cost-Cutting and Excellent Care Not Mutuallly Exclusive
- The Key to Safe Bone Marrow Transplants Revealed