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Bashir Zikrai

Class Notes

News from and about our graduates.

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Circling the Dome

If the worst happens, getting serious with Semper Fi, tuning in to tranquility, easing the end, shooting for the stars and more.

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Medical Rounds

The freeze is on, seeing the light, thinking small, a urine test for bladder cancer, heart failure culprit collared, asthma’s new hot zones and more.

Daniel Todes

Hopkins Reader

Daniel Todes unveils the genuine Pavlov. plus: Charting the health of the nation’s first ladies; and Howard W. Jones, now 104, looks back on his quest to achieve in vitro fertilization in the U.S.

Forum

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Letters

This issue’s letter from the editor and reader responses.

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Second Opinion

Expensive hospital renovations have little impact on how patients rate their care.

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Post-Op

We must take bold steps to hold on to early-career scientists.

In Focus

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It's a Match

After years of schooling, countless applications and many nerve-racking interviews, fourth-year medical students gathered on March 20 in the Armstrong Medical Education Building for the time-honored tradition of Match Day. Shrieks, hugs and tears of joy were the order of the day as, precisely at noon, members of the Class of 2015 tore open envelopes to discover which hospital and specialty program accepted them for their residency.

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Horizons

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Crystal Ball on Frailty?

The frail elderly are easy to spot: they tend to be thin and weak, with little energy and a slow and unsteady gait. first recognized as a medical condition in 2001, frailty is too often the beginning of the end.

Now a Johns Hopkins team has found that the amount of mitochondrial DNA in peoples’ blood directly relates to how frail they are medically. this DNA may prove to be a useful predictor of overall risk of frailty and death from any cause some 10 to 15 years before symptoms appear— giving doctors the head start they need to improve fitness in at-risk individuals with drugs or lifestyle changes.

"We don’t know enough yet to say whether the relationship is one of correlation or causation, but either way, mitochondrial DNA could be a very useful biomarker in the field of aging," says Dan Arking, associate professor of genetic medicine. the scientists reported on their work in the online Journal of Molecular Medicine.

Photo Credit: Mitchell / iStock

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