More Arrows in the Arsenal
Dramatic advances in immunotherapy offer new options for patients with advanced melanoma.
Often misdiagnosed as dementia, adult hydrocephalus can be reversed, notes Daniele Rigamonti. Plus: Coping with bipolar disorder and a spotlight on aging eyes.
The Big Reveal
The 110 fourth-year medical students in Hopkins’ Class of 2014—together with family members, mentors, and friends—gathered at Hopkins’ Armstrong Building on March 21 for the rite of passage known as Match Day. A noontime countdown, followed by the collective ripping of envelopes, quickly dissolved into hugs, tears of joy, champagne toasts, and cross-country phone calls for those assembled, as they celebrated news of their destinations for the next three to seven years of residency training. Notably, a third of the class (some 36 graduates) will train at hospitals that are part of the Johns Hopkins Medicine system.
View a video of Match Day 2014.
Studying epithelial cells (red), which give rise to 85 percent of all cancers, Johns Hopkins researchers turned on a gene called Twist1, with dramatic results. Within 24 hours, dozens of individual cells (green) began to migrate past the epithelial boundary and into the gel beyond. This and other findings from the lab of Andrew Ewald, assistant professor of cell biology and oncology, could help clarify the molecular changes required for cancer cells to metastasize.