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Johns Hopkins Medicine News Roundup

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PodMed

PodMed is a weekly podcast looking at the top medical stories of the week for people who want to become informed participants in their own health care. With Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine, and Rick Lange M.D., professor of medicine at Johns Hopkins and vice chairman of medicine at the University of Texas Health Science Center at San Antonio.

 

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All podcasts from 2010- 2005 have been moved to there archived pages. 2011 podcasts can be found below.

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International Medical Headlines- December 2011

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Program notes:
 
0:12  Tuberculosis treatment
1:11  Combination of isoniazid and rifapentin
2:12  Used to be prevalent in the US
3:12  Medications resulting in the majority of emergency hospitalizations in seniors
4:12  Really what is seen in clinical practice
4:54  Atrial fibrillation review
5:52  Successful aging resulting in more a fib
6:20  Treatment of malaria during pregnancy
7:20  Increased risk of miscarriage
8:12  No difference in adverse effects
9:11  Pregnancy is higher risk for malaria
10:04 End

Week of 
December 26, 2011

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This week’s topics include the best way to close a stuffed turkey, elf life, the shelf life of fruitcake, and a reindeer-associated virus.
 
Program notes:
 
0:33  Best way to close a turkey
1:28  Staples were best way
2:27  Eternal fruitcake
3:29  Fruitcake up for auction
4:27  Biochemical explanation for why it lasts
5:05  Elf life
6:04  Older elves make dolls, trains, wagons
7:04  Don’t know what the females are doing
7:19  Zoonosis for Christmas
8:16  Call it Comet or Cupid
9:22  End

Week of 
December 19, 2011

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This week’s topics include when to transfuse people at risk, ADHD medications and cardiovascular risk, PCI in centers without bypass capability, and what’s behind stillbirth.
 
Program notes:
 
0:33  Safety of ADHD medications
1:19  Modestly increase blood pressure and heart rate
2:18  About 4% of adults affected
2:34  Factors associated with stillbirth
3:25  Cause known in about 70% of cases
4:20  Doing complete studies important
4:33 PCI and centers without bypass
5:25 Emergency bypass surgery rarely needed
6:24  It’s not having a surgeon available that makes it safer
7:07  When should people be transfused?
8:10  Transfusion or not based on hemoglobin
9:07  Don’t need to transfuse as often as we do
10:21 End

Week of 
December 12, 2011

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This week’s topics include knee pain, flu vaccines in pregnant women, second generation antidepressants, and antibiotic use in children.
 
Program notes:
 
0:47  Flu vaccine in pregnant women
1:47  Antibodies in mom and baby
2:45  Antibiotics in kids
3:44  Many were broad spectrum
4:36  Knee pain in adults
5:35  No increase in osteoarthritis but pain 2 or 3 times higher
6:39  Reduced waiting for knee replacement
7:25  Second generation antidepressants
8:25  No real difference in how well they treat depression
9:27  Physicians must become very familiar with these meds
10:22 End

Week of 
December 05, 2011

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This week’s topics include managing blood thinners at home, 4 most common medications associated with emergency hospitalizations in the elderly, door in door out time for heart attack treatment, and free medications don’t seem to help.
 
Program notes:
 
0:29  Door in door out times for heart attack treatment
1:27  Many people need to be transferred
2:32  Transport to appropriate facility initially
3:32  Other ways to get arteries open
4:01  Paid for medications don’t improve compliance
5:02  Less than half got all their medications
6:03  Very complex medicine regimens
6:17  4 common medications that cause seniors to need hospitalization
7:15  Two diabetes and two blood thinning medications
8:12  Unique problems of elderly
8:30  Monitoring blood thinners at home
9:28  Less likely to have clotting events
10:50 End

Week of 
November 28, 2011

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This week’s topics include vibration to improve osteoporosis, sodium and potassium excretion and cardiovascular risk, use of daily inhaled steroids in kids at risk for asthma, and sepsis and atrial fibrillation.
 
Program notes:
 
0:31  Vibrating platform and osteoporosis
1:30  One of three groups with varying treatments
2:27  Staying in hotels with vibrating beds
3:01  Association between bloodstream bacterial infections and atrial fibrillation
4:02  Examined over 49,000 with severe sepsis
5:00  Potassium and sodium excretion and cardiovascular events
6:00  People at low and high ends of sodium were at increased risk
7:01  In low risk individuals sodium intake may not be so important
7:54  Should kids at risk for asthma take daily steroids?
8:56  Either daily or intermittently
9:40  Parents very motivated
10:34 End

Week of 
November 21, 2011

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This week’s topics include niacin and statins, impact of cardiac CT, a new drug to raise HDL cholesterol, and remote versus in person weight loss programs.
 
Program notes:
 
0:40  Weight loss program in person or remote
1:33  Fifty percent of obese say physician never asks
2:33  Can accommodate individual needs
3:17  New drug to raise HDL cholesterol
4:19  Evastrabib raised HDL over 100%
5:17  We don’t know if raising HDL will help
5:28  Adding niacin to statins
6:26  Niacin group slight increase in strokes
7:06  Cardiac CT and subsequent interventions
8:06  Medicare beneficiaries, and procedures
9:05  Lots of data missing
10:14 End

International Medical Headlines- November 2011

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This month’s topics include a new malaria vaccine, the best strategy for managing coinfection with HIV and TB, and the World Health Summit.
 
Program notes:
 
0:18  Malaria vaccine
1:18  Very hard to develop effective immunity
2:16  This vaccine is protective
3:18  Increased risk of seizures
4:19  Treating coinfection with TB and HIV
5:13  Immune reconstitution syndrome
6:18  Resistant TB happens because people don’t take meds
7:10  World Health Summit
8:13  Global health framework
9:15  Role of Germany in public health
10:15 Working through how to do public health now
11:22  End

Week of 
November 14, 2011

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This week’s topics include transplanting livers in those who’ve abused alcohol, too many neurons in autism, extracranial bypass for some blocked blood vessels in the brain, and doctors who order stress tests and financial interests.
 
Program notes:
 
1:01  Physician billing and stress test ordering
2:04  13% of physicians who billed ordered the test
3:01  Shifted to hospitals
3:17  Neuron number and autism
4:10  Analyzed prefrontal cortex in both autistic and normal kids
5:11  Connection pruning as well as reduced neuron number
6:12  Take the next step to look at hard wiring in brain
6:33  Should we transplant livers in those with alcoholic hepatitis
7:32  Benefits of transplantation lasted over two years
7:53  Extracranial bypass
8:53  Recurrent stroke the same but in first month medical therapy much better
9:49  Medical therapy has improved so much
10:49 Antiplatelet agents
11:11 End

Week of 
November 7, 2011

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This week’s topics include an oral agent for cystic fibrosis, safety of metal detectors for folks with pacemakers, breast cancer risk and alcohol consumption, and ADHD medications and heart risk.
 
Program notes:
 
0:27  Oral medication for cystic fibrosis
1:24  Breakthrough study for one type of CF
2:24  Strategies to move mucus not always effective
3:13  ADHD medications and heart impact
4:13  Matched cohort both taking medications and not
4:53  Cardiac devices not at risk in airports
5:48  Walking through metal detectors fairly safe
6:42  No change in device function with handheld metal detectors
7:24  Breast cancer risk and alcohol consumption
8:27  Low levels of alcohol consumption modestly increased risk
9:23  Weigh the risk and benefit
10:30 End

Week of 
October 31, 2011

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This week’s topics include Sherlock Holmes style investigation of the E. coli outbreak in Germany, lack of benefit of routine chest x-ray and lung cancer mortality, bisphenol A and behavior issues in children, and hormonal changes related to weight loss.
 
Program notes:
 
0:39  E. coli outbreak
1:30  Hemolytic uremic syndrome
2:27  Even after identifying bean sprouts people didn’t remember
3:30  National German database
3:39  Screening chest x-ray and lung cancer mortality
4:39  Compliance very high
5:25  Bisphenol A and impact on behavior in children
6:25  Maternal measurements during pregnancy
7:30  Prospective study unlikely
8:14  Weight loss and hormones
9:15  Hormonal changes persist after weight loss
10:28 End

Week of 
October 24, 2011

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This week’s topics include a new vaccine for malaria, best practices for screening mammography, limiting TV watching for the very young, and new recommendations for managing ADHD.
 
Program notes:
 
0:24  Limit TV viewing in children younger than 2
1:30  Lack the ability to appreciate content
2:30  Reduce time for other activities needed for development
3:10  ADHD diagnosis and management
4:08  Medications in older children
5:03  Two studies looking at mammography
6:03  Women who had annual screening had more false positives
7:04  Digital mammography better in dense breasts
7:23  Malaria vaccine
8:22  16,000 children to enroll
9:20  Hybrid vaccine developed
10:22 End

Week of 
October 17, 2011

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This week’s topics include folate and language development in kids, vitamin E, selenium and prostate cancer, supplements and mortality in older women, and Barrett’s esophagitis and esophageal cancer.
 
Program notes:

0:36  Barrett’s esophagitis and esophageal cancer
1:35  Nationwide study in Denmark
2:45  Still a risk factor and difficult disease to treat
3:26  Older women and risk of death relative to supplements
4:30  Use of multivitamins increased risk of mortality
5:25  Just a survey, not much baseline data
6:02  Vitamin E, selenium and prostate cancer
7:04  Increases risk of prostate cancer when taken alone
7:25  Folate supplementation in pregnancy
8:26  Those whose mothers took folate had children with decreased risk
9:33  In US already supplement in diet
10:13 End

Week of 
October 10, 2011

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This week’s topics include use of social media to identify alcohol use problems in college students, advance directives and their impact on healthcare costs, surgery at the end of life, and nutritional supplements for lung health in people on ventilators.
 
Program notes:
 
0:36  Use of social media to assess alcohol use problems in college kids
1:33  Few students get screened but 98% are on social media
2:36  Gives us an opportunity to identify those with a problem
3:32  These are publicly displayed sites
4:01  Pharmaconutrition
5:02  Routine nutrition or fish oil supplements when on ventilator
6:05  Advance directives and their impact on medical costs
7:02  Medicare beneficiaries who died and use of advance directives
8:03  When you talk to patients about advance directives
8:26  Surgery at the end of life
9:26  Standardize surgical interventions
10:38 End

Week of 
October 3, 2011

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This week’s topics include diagnosing strep based on community incidence, predicting who will develop erectile dysfunction after prostate cancer treatment, treating obsessive compulsive disorder in kids, and the right interval for dialysis.
 
Program notes:
 
0:49  Obsessive compulsive disorder in kids
1:44  Does cognitive behavioral therapy add to OCD treatment?
2:37  Needs to be done in a rigorous fashion
3:01  Community survey to inform strep infection diagnosis
4:03  If incidence is added it improves diagnosis
5:01  Biosurveillance and health information technology
5:37  Proper interval for hemodialysis to take place
6:37  Does death risk increase with increased interval?
7:27  Important to understand why
7:43  Predicting erectile dysfunction after prostate cancer treatment
8:45  Based on a multitude of factors they could predict fairly accurately
9:35  If treatments are equally successful, which are least likely to cause side effects
10:09 End
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International Medical Headlines- September 2011

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Johns Hopkins Medicine is pleased to provide our many international listeners who have requested more emphasis on global health problems with a monthly look at the international medical headlines with Michael Klag, MD, MPH, dean of the Johns Hopkins Bloomberg School of Public Health, and Elizabeth Tracey, MS, director of electronic media for Johns Hopkins Medicine.

Week of 
September 26, 2011

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This week’s topics include rotavirus vaccine, EKG update, treating varicose veins, and the relationship between stroke and depression.
 
Program notes:
 
0:36  Should you have an EKG if you don’t have heart disease symptoms?
1:34  Ways of screening for being at risk
2:26  C for cholesterol, D for diet
3:02   Stroke and depression
4:02  Range of conditions affected by depression
5:03  Don’t know if treatment will reduce risk
5:23  What is the best treatment for varicose veins
6:15  Vein stripping or laser ablation
7:15  Higher phlebitis with laser
7:55  Effectiveness of rotavirus vaccine
8:55  Dropped costs dramatically even among unvaccinated
10:30 End

Week of 
September 19, 2011

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This week’s topic is the obesity issue of the Lancet.
 
Program notes:
 
0:31 4 part series in the Lancet
1:33  Two part epidemic from first part of century
2:31  In developing world bimodal distribution
3:30  Using the US as a model
4:28  Can’t be left to the individual
5:24  Used to think it was simply decreasing intake
6:25  Lose more weight with both exercise and decreased intake
7:30  Very few countries are monitoring
8:28  Put nutritional labeling on front of package
9:21  Prevention most effective intervention
10:22 End

Week of 
September 12, 2011

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This week’s topics include lifestyle and diabetes risk in older people, NSAIDS and miscarriage, gastric bypass versus duodenal switch, and intracranial carotid stenting.
 
Program notes:
 
0:24  NSAIDs and miscarriage risk
1:20  Women who did use NSAIDs may increase risk by 2.5 times
2:20  Didn’t actually measure the dose
3:20  Not just a single study convincing
3:35  Comparing two types of obesity surgery
4:35  Long term complications with duodenal switch
5:28  Lifestyle and diabetes risk in elderly
6:33  Diet, moderate alcohol, exercise, decrease risk
7:33  Benefits no matter how old you are
8:01  Intracranial carotid stenting
9:01  Increased risk to 15% with stenting
10:01  How good medical therapy is
10:40 End
PodCast

Week of 
September 06, 2011

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This week’s topics include an update on CPR, chocolate and heart disease, tamoxifen and breast cancer, and a new anticoagulant medication for people with atrial fibrillation.
 
Program notes:
 
0:22  Chocolate and heart disease
1:17  Dietary survey
2:15  Temper enthusiasm since it’s not definitive
3:00  CPR update
4:01  Almost 10,000 patients CPR before defibrillation
5:07  Future studies need to be quality improvement attempts
6:03  Anticoagulant for people with atrial fibrillation
7:01  Apixiban superior to warfarin
7:52  Tamoxifen in preventing breast cancer recurrence
8:50  Decreased risk of death by about a third
9:50  Used in pre or perimenopausal women
10:16 End
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PodCast

Week of 
August 29, 2011

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This week’s topics include ambulatory monitoring of blood pressure, changes in medication following hospitalization, the power of food to lower cholesterol, and use of an antibiotic in COPD.
 
Program notes:
 
0:25  Use of a 24 hour monitor to diagnose high blood pressure
1:27  Compare routine measurement to home monitoring to ambulatory
2:25  Smart phone ap for high blood pressure
2:47  Zithromax for COPD
3:45  Took 1100 people with COPD and used Zithromax
4:45  Use of antibiotics create resistant organisms?
5:14  Unintentional stoppage of medications after hospitalization
6:15  At discharge 5-20% of medications discontinued
7:15  May be good reasons to stop
7:45  Cholesterol lowering foods
8:41  Either low fat diet but also foods that lower cholesterol
9:12  Lowered cholesterol by 13%
10:14 End
PodCast

Week of 
August 22, 2011

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This week’s topics include surgery for hip fractures and the impact of delay, coronary artery calcium scanning efficacy, emergence of resistant malaria, and a new medication for congestive heart failure.
 
Program notes:
 
0:39  Coronary artery calcium scanning
1:39  Putting everyone on statins?
2:25  Electron beam computed tomography
3:31  Knowing score doesn’t often change behavior
4:00  Hip fracture surgery, early or late?
5:02  Doesn’t appear to be risky to delay
5:51  New medication for congestive heart failure
6:51  Allows more vigorous contraction of heart muscle
7:35  Resistant malaria development
8:35  After nets and combination therapy, a reduction seen
9:32  Just an observation but doesn’t prove causality
10:26  End
PodCast

Week of 
August 15, 2011

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This week’s topics include soy and menopausal symptoms, geographic variations in angiography, phlebotomy and anemia in those with heart disease, and ten year results from deep brain stimulation for Parkinson’s disease.
 
Program notes:
 
0:31  Variations in angiography around the country
1:30  Why did hospitals have a high or low percentage?
2:24  Implies it’s being done in people who don’t need it
3:21  Phlebotomy and anemia
4:21  20% of people who came in normal became anemic
5:22  Soy supplements and menopausal symptoms
6:22  No difference in bone mineral density but did increase hot flashes
7:24  Well conducted trial and no benefit seen
7:46  Ten year results from deepThis week’s topics include soy and menopausal symptoms, geographic variations in angiography, phlebotomy and anemia in those with heart disease, and ten year results from deep brain stimulation for Parkinson’s disease.
PodCast

Week of 
August 8, 2011

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This week’s topics include a new way to assess newborns for heart problems, texting to improve malaria care in Africa, a disappointing report about hospitalists, and guidelines for managing COPD.
 
Program notes:
 
0:26  Texting to help manage malaria treatment
1:23  Improved adherence to guidelines by healthcare workers
2:09  Oximetry to assess newborns for heart problems
3:07  Doesn’t add a lot to existing regimens
3:36  Hospitalists aren’t having the impact on costs
4:30  Use of medical care in hospital and outpatient
5:31  Need to look at continuum of care
6:31  Guidelines for managing COPD or emphysema
7:32  Don’t take steroids first
8:30  Need research on second agent addition
9:15  Smoking cessation primary recommendation
10:01 End
PodCast

Week of 
August 1, 2011

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This week’s topics include a way to make kidney transplants last longer, the predictive value of sentinel nodes in breast cancer, Medicare Part D, and NSAIDs and Alzheimer’s disease.
 
Program notes:
 
0:25  Way to make kidney transplants last longer
1:22  High risk sensitized recipients
2:21  Not much risk related to plasmapheresis
3:13  Breast cancer sentinel node impact
4:14  About 10% had metastasis in the sentinel nodes
5:11  Adjuvant therapy helps
5:40  Medicare part D and medical care
6:40  Costs went down related to inpatient admissions
7:28  Alzheimer’s disease and NSAIDs
8:18  Increase risk of dementia in those with symptoms already
9:13  In those without symptoms may help
10:36 End
PodCast

Week of 
July 25, 2011

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This week’s topics include HIV treatment in Uganda, exercise and cognitive decline, calorie content in restaurant foods, and diet and diverticulitis.
 
Program notes:
 
0:24 HIV treatment in Uganda
1:23 Organization administers HIV therapy to infected
2:22  Need to expand availability of drugs
2:47  Diet and ability to prevent diverticulitis
3:45  Vegetarians or vegans compared with meat eaters
4:45  Dietary changes also lower risk of cancer
5:03  Energy content of restaurant foods**
6:03  Many foods underreported calorie content
7:03  Exercise and cognitive decline
8:01  Not only exercise but daily activity
9:01  Another study showing the same thing
10:15 End
PodCast

Week of 
July 18, 2011

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This week’s topics include the impact of maternal smoking, sodium and potassium and death, placebos and asthma management, and family history of cancer over time.
 
Program notes:
 
0:22  Asthma and placebos
1:27  Active treatment did improve lung function
2:25  Whatever makes a patient feel better works
3:07  How changing family history impacts cancer risk assessment
4:15  Would change screening interval
4:36  Maternal smoking and birth defects
5:38  Birth defects raised risk by 10-25%
6:39  Sodium and potassium and mortality**
7:30  Direct relationship with high potassium and low sodium
8:34  Do it by diet not supplements
9:49  End
PodCast

Week of 
July 11, 2011

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This week’s topics include the dangers of rural hospitals, cardiac events due to a smoking cessation drug, sudden cardiac death and lifestyle factors in women, and inappropriate stent placement.
 
Program notes:
 
0:27  Chantix and heart events**
1:23  Twice as likely to quit smoking but increased risk
2:20  Long term effects of stopping smoking?
3:21  What women can do to reduce their risk of sudden cardiac death
4:25  Four healthy lifestyle choices reduced risk by 92%
5:25  Only about 25% eat a healthy diet
5:52  Performance of rural hospitals
6:46  Critical access hospitals don’t do processes properly
7:45  emedicine can transform care
8:13  Appropriateness of PCI
9:19  So many being done inappropriately
10:13  Changing paradigm so review is done
11:05  End
PodCast

Week of 
July 01, 2011

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This week’s topics include use of CT to prevent lung cancer death, sunscreens and melanoma, text messaging and smoking cessation, and type 1 diabetes and congestive heart failure.

Program notes:

0:25  Use of text messaging to assist smoking cessation**
1:25  Twice as likely to stop smoking
2:15  Tailor messages to individual
2:42 Congestive heart failure in type 1 diabetes
3:44  Increased risk relative to blood sugar control
4:43  Difference in type 1 and 2 mechanisms
5:32  Using CT to screen high risk people for lung cancer
6:30  20% less likely to die
7:30  How cost effective?
7:52  Melanoma prevention with sunscreens
8:43  Daily use resulted in 50% reduction
10:15 End

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PodCast

Week of 
June 24, 2011

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This week’s topics include possible dangers of high dose statins, chasing down the E. coli epidemic, door in door out times, and multiple blood pressure measurements

Program notes:

0:23  E. coli outbreak
1:12  Over 800 developed hemolytic uremia
2:10  Were able to type within 2 days
3:08  High dose statin therapy and diabetes
4:04  Percentage sounds the same but risk isn’t
5:01  Door in door out for heart attack treatment
6:02  Appropriate transfer only 11% of the time
7:03  In the past we’ve looked at door to balloon time
7:24  Multiple blood pressure measurements help**
8:10  Measured at home, clinic or a research measurement
9:05  Need to do multiple, five or six
10:22 End

PodCast

Week of 
June 17, 2011

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This week’s topics include malpractice in inpatient and outpatient settings, parental attitudes toward childhood vaccines, ambulance drive-bys, and TV and mortality.

Program notes:

0:38  Parental attitudes toward having their children vaccinated
1:35  Overwhelming majority will have their children vaccinated
2:30  About a third of parents worry about autism still
3:26  Need to be aware of concerns
3:40  TV and health impact **
4:25  Unhealthy eating, sedentary
5:27  13% increased mortality risk
6:06  Negative outcomes associated with ambulance diversion
7:01  Higher mortality persisted out to one year
7:44 Malpractice in outpatient vs. inpatient settings
8:40  Outpatient usually was a diagnostic issue
9:40  Check out podmedblog
10:01 End

PodCast

Week of 
June 10, 2011

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This week’s topics include screening for ovarian cancer, a new agent to prevent breast cancer in high risk women, remote management of treatment for hepatitis C, and mentholated cigarettes.

Program notes:

 0:38  Ovarian cancer screening
1:18  Screened with ca125 and ultrasound
2:04  Screening isn’t helpful and doesn’t reduce deaths
3:04  Nonspecific symptoms
3:30  Breast cancer prevention
4:20  65% reduction in risk with exemestane
5:21  Only very few women take existing medications
5:38  Remote treatment for hepatitis C
6:37  Rural physicians call into university center
7:34  Barriers include who will pay?
8:22  Mentholated cigarettes **
9:40  Barriers to removal?
10:32 End

PodCast

Week of 
June 03, 2011

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This week’s topics include sports and energy drinks in kids, sleep duration and obesity in children, two common drugs and their association with diabetes, and niacin and heart disease.

Program notes:

0:55  Please send an email to etracey@jhmi.edu if you listen
1:09  Two common drugs and diabetes risk
2:06  Adverse event reports and evidence of elevated glucose
3:03  AER reports confirmed in hospital populations
4:04  Niacin and its lack of benefit
5:01  Niacin raises HDL and lowers triglycerides
6:03  Sports and energy drinks in children **
7:04  Routine exercise no benefit
8:01  Calories and carbohydrates high
8:23  Sleep duration and weight in kids
9:20  Short duration of sleep they eat more
10:36 End

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PodCast

Week of 
May 27, 2011

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This week’s topics include a lack of benefit in coronary CT screening, aspirin versus a new agent in stroke prevention, lung remodeling in asthma and locomotion training after stroke.

Program notes: 

0:27  Stroke patient rehabilitation methods
1:24  Does body weight supported treadmill rehab work?
2:08  Newer doesn’t mean better
3:01  Aspirin vs. a newer agent after stroke
4:01  Overall no difference but one subgroup did
5:02  Coronary CT for screening **
6:01  Overdiagnosis common
7:06  Less invasive testing?
7:46  Airway remodeling in asthma
8:43  Caused both inflammation and constriction of bronchi
9:28  Does explain why steroids may not prevent remodeling
10:16 End

PodCast

Week of 
May 20, 2011

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This week’s topics include third agents in diabetes treatment, the utility of telemedicine, treating one partner who is HIV positive to prevent transmission, and PPI or surgery for GERD.

Program notes:

0:37 If you listen send us an email! etracey@jhmi.edu
0:56 Treating one HIV positive partner
1:43 Early treatment was very effective
2:16 Barriers include cost and real world circumstances
2:48 Heartburn treatments **
3:33 People continued proton pump inhibitors or had surgery
4:20 Some patients reluctant to take medications long term
5:10 Telemedicine in the ICU
6:10 A care plan and assessed adherence
7:04 May not need telemedicine to do this
7:49 Addition of a third agent for diabetes management
8:31 All reduce blood sugar equivalently
9:05 Weight loss, exercise, etc
10:05 End

PodCast

Week of 
May 13, 2011

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This week’s topics include use of medical therapy for people with heart disease, risk of NSAIDs in those who’ve had a heart attack, overuse of colonoscopy, and physician attitudes toward continuing medical education (CME).

Program notes:

0:40  Are you a listener? We need to hear from you. Send an email to etracey@jhmi.edu
1:21  Non steroidal anti-inflammatory drugs and second heart attack**
2:20 Increased risk of death or recurrent heart attack by 50%**
3:10  Naprosen with lowest risk
4:00  Medical therapy isn’t used as often as it should be in CAD
5:06  COURAGE trial hasn’t changed practice
6:00  Aren’t convinced that medical therapy is as good as a procedure
6:31  Colonoscopy repeated too soon
7:37  Why are so many repeated?
8:16  Physician attitudes toward CME
9:16  Estimated $1500 per year for CME now
10:32 End

PodCast

Week of 
May 06, 2011

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This week’s topics include infants and supplements, asthma medications, bisphosphonates and fracture risk, and dietary salt.

Program notes:

0:29  Salt study refutes previous ones
1:29  Highest increase in salt has a lower risk of death
2:28  As we age we develop high blood pressure
2:42  Bisphosphonates and fracture risk
3:36  Who sustained femoral fracture?
4:31  These drugs affect one aspect of bone physiology
5:12  Asthma medications **
6:12  Which drug is best for both primary and supplemental therapy?
7:19  Oral, once a day medications
8:03  Supplements used in infants
9:04  Outbreak of diarrhea secondary to supplement use
10:15 End

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PodCast

Week of 
April 29, 2011

Related Blog**

This week’s topics include armadillos and leprosy, LAM treatment, IQ testing, and fatty liver disease in kids

Program notes:

0:34  Armadillos and leprosy
1:23  Genetic analysis on animals
2:23  Identification of zoonosis
3:30  IQ testing **
4:24  Meta-analysis and testing directly
5:17  Payment added IQ points
6:00  Treatment of fatty liver disease in kids
7:01  Neither adult treatment helped in kids
7:47  LAM treatment
8:46  Mother started the LAM foundation
9:23  Rapamycin stabilized
10:22 End

PodCast

Week of 
April 22, 2011

Related Blog**

This week’s topics include kids who fail antiretroviral therapy, when such therapy should be started, new criteria for Alzheimer’s disease, and the significance of triglycerides.

Program notes:

0:29  Message to listener
1:10  New criteria for Alzheimer’s disease
2:19  One of the concerns is we apply treatments too late
3:10  Guideline committee states it’s a clinical diagnosis
4:00  New criteria regarding triglycerides
5:01  Potentially cause pancreatitis
6:09  Focus less on triglycerides
6:27  Number of kids who fail anti-HIV therapy**
7:27  Can become resistant to treatment
8:01  When to initiate therapy in HIV infected
9:05  Treating earlier has downsides
10:02  Are you motivated to take them?
10:35  End

PodCast

Week of 
April 15, 2011

Related Blog**

This week’s topics include shedding of herpes viruses even when no lesions are present, treating nerve pain related to diabetes, physicians recommending one treatment to patients but another to themselves, and risks of acne treatment with antibiotics.

Program notes:

0:32  Physicians do as I say but not as I do?**
1:38 
Physicians chose therapy that had higher mortality
2:35  Told patients less risky behavior
3:30  Use of antibiotics for acne treatment
4:39  Unlike current dogma, these didn’t get more resistant organisms
5:35  Viral shedding in people without lesions in herpes infections
6:35  Those without lesions still shed virus
7:26  Don’t know how long they’ve been infected
8:10  Managing diabetic neuropathy
9:17  Topical capsaicin
10:38 End

PodCast

Week of 
April 08, 2011

Related Blog**

This week’s topics include repairing the heart through the skin, patient management of blood thinners, overdoses due to opioids, and whether PSA should be tested for at all.

Program notes:

0:29  Study suggesting that PSA is not helpful at all
1:24  Rate of death didn’t differ between screened and unscreened men
2:24  For those who want testing, just watching may be just as effective
3:26  New markers on the horizon
3:51  Patient involvement in blood thinning medicine management
4:52  Inconvenient and costly going to a clinic to have monitoring
5:50  Many patients are not appropriate
6:50  Monitoring devices often at home
7:05  Opioid medication and death**
8:04
  What can we do to use them but keep people safe?  8:21  Mitral valve replacement
9:21  Was helpful in many but some still needed surgery
10:29 End

PodCast

Week of 
April 01, 2011

Related Blog**

This week’s topics include the dangers of social media, a new drug for hepatitis C, managing obesity in frail elderly people, and airport scanner risk.

Program notes:

0:28  Dangers of social media for children**
1:22  22% of teenagers log on more than 10 times per day
2:21  Parents need to talk with their kids about online use
3:23  Blog has online resources
3:35  Exposure to radiation via airport scanners
4:35  Routine radiation exposure every day
5:11  Treating obesity in frail older adults
6:11  Randomized to diet, exercise, both or nothing
7:21  New treatment for hepatitis C
8:17  Cure with traditional agents 30% effective
9:15  Addition of protease inhibitors helps
10:14 End

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PodCast

Week of 
March 25, 2011

Related Blog

This week’s topics include use of fibrates in the US and Canada, child safety seats, diabetes medications, and the risks of exercise and sex.

Program notes:

0:23  Risks of sudden death after sex and exercise
1:26  Risk factors not independently assessed
2:22  Convincing people not to have sex?
3:22  Other things may be associated but we don’t know
3:40  Car seats for children
4:30  Recommendations related to their size and weight
5:31  Teenagers even in back seat
6:20  Use of fibrates
7:23  Don’t be persuaded by direct to consumer ads
7:50  Two different studies related to diabetes meds
8:40  Observational studies of almost a million people
9:27  Glitazones very widely prescribed in US
10:26  No need for medications with lifestyle interventions
10:50 End

PodCast

Week of 
March 18, 2011

Related Blog

This week’s topics include high dose anticlotting drugs don’t help, bypass versus stent placement and quality of life issues, a new virus in China, and treating inner city kids with asthma.

Program notes:

0:27 Bunyavirus identification
1:31 Mortality of about 30%
2:28 Can track down vector
3:11 Use of an anti-antibody medication and asthma
4:12 Placebo or antibody decreased symptoms
5:11 Considered therapy to nonresponders
5:21 Angina and bypass surgery or stents
6:12 Quality of life issues
7:12 Stenting more likely to need another procedure
7:43 Use of anticlotting agent clopidogrel
8:43 Doubling dose isn’t helpful
9:30 Aspirin and clopidogrel generally recommended
10:04 End

PodCast

Week of 
March 11, 2011

Related Blog

This week’s topics include cannabis and psychosis, lack of benefit with PSA velocity, stress, infertility and pregnancy, and cause-specific death and diabetes.

Program Notes:

0:46  Impact of stress on infertility treatment and pregnancy
1:45  Procedure itself was stressful
2:40  Cannabis and the development of psychosis
3:36  Doubled the risk of frank psychosis
4:28  Is this persistent?
5:21  PSA velocity isn’t helpful
6:21  Does it detect aggressive prostate cancer?
7:21  All men biopsied at end of 7 years
8:05  Whether diabetes contributes to different causes of death
9:03  A fifty year old man with diabetes dies 6 years earlier than men without
10:31  End

PodCast

Week of 
March 04, 2011

Related Blog

This week’s topics include steroids for nasal polyps, Facebook and TB, making medical decisions for others, and BMI for Asians.

Program notes:

0:57  Facebook and an outbreak of TB
1:55  Usual epidemiology didn’t work
2:54  Social networking as an epidemiology tool
3:48  Podmedblog
3:58  Lack of association between obesity and death in Asians
4:58  Indian and Bangladeshi populations
5:35  Making healthcare decisions for others
6:30  Negative effects may last months or years
7:35  We all need to inform our decision makers
7:55  Steroid therapy for nasal polyps
8:56  Oral steroids followed by topical improved more
9:44  Patients should be seen by ENT physician
10:38 End

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PodCast

Week of February 25, 2011

Related Blog

This week’s topics include driving after a stroke, falls from cribs, cell phones and brain activity, and life on the farm and childhood asthma.

Program notes:

0:23 Cell phones and your brain
1:28 Used PET scanning and measured activity
2:11 Just speech in your ear causes metabolism to rise
2:50 Life on the farm and childhood asthma
3:46 Exposed to increased number and variety of microbes
4:36 This study suggests early modulation of immune system possible
4:51 Cribs as a cause of injury
5:47 First study to look at what is involved in the injury
6:37 How to assess driving ability after stroke
7:37 Three tests that can predict failure of on road driving test
8:37 No more likely to have accidents than those who haven’t had a stroke
9:56 End

PodCast

Week of February 18, 2011 

Related Blog

This week’s topics include using asthma medications only when needed in teenagers, the impact of fiber on mortality, FDA oversight of devices, and obesity, knee arthritis and quality of life.

Program notes:

0:24 FDA oversight of medical devices
1:20 More risky for less rigorous oversight
2:26 Can strengthen oversight with manufacture inspection
3:12 Fiber consumption and mortality
4:15 Lowered risk of death by 24-59%
5:02 Obesity, knee osteoarthritis and mortality
6:02 Reduce obesity and avert many knee replacements
7:02 Perhaps help modify behavior
7:17 Kids with asthma may be able to reduce medications
8:06 Children often aren’t compliant
9:09 Worth a trial among kids with asthma
10:17 End

PodCast

Week of February 11, 2011

Related Blog

This week’s topics include an implantable monitor for congestive heart failure, in utero surgery for one form of spina bifida, more evidence that axillary node dissection may not be necessary, and response to vaccination in infants of HIV infected moms.

Program notes:

0:42  Axillary node dissection in breast cancer
1:45  With a positive sentinel lymph node thought necessary
2:35  The presence of micrometastasis doesn’t impact survival
3:25  Mothers who are HIV positive and infant vaccination
4:25  Do they respond to vaccinations?
5:20  In utero surgery for one form of spina bifida
6:21  Infants who got surgery much more likely to walk
7:30  Monitor implanted for congestive heart failure
8:22  In pulmonary artery
9:26  Great advance in management of CHF
10:09 End

PodCast

Week of February 4, 2011

Related Blog

This week’s topics include evaluation of low back pain, new antibiotic for Clostridium difficile infection, the federal dietary guidelines, and vaccination for HPV in males.

Program notes:

0:27    New federal dietary guidelines
1:23    Caloric balance and nutrient density
2:33    Enlist the food industry
3:11    Imaging and evaluation of low back pain
4:09    Why are people referred for imaging?
5:10    Patients demand imaging themselves
5:46    Use of HPV vaccine in males
6:47    Should be gender neutral
7:37    Only about 44% of girls have had one dose
8:03    New treatment for Clostridium difficile
9:02    Stays in GI tract and kills the bug, not just suppresses
10:02  Risk for infecting others
10:40  End

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PodCast

Week of January 28, 2011

Related Blog

This week’s topics include smoking and breast cancer, a brief intervention for insomnia, the benefits of stroke centers, and a suction device and CPR.

Program notes:

0:50  CPR suction device benefits
1:30  Active compression decompression CPR
2:17  Overall survival still dismal
3:01  Stroke centers and their benefit
4:01  How troublesome to get to a stroke center?
5:09  Wasn’t because the hospital was overall better
5:23  Cigarette smoking and breast cancer risk
6:20   Women who smoke had modestly increased risk
7:11  Brief behavioral intervention and insomnia
8:08  55% of participants said insomnia resolved
9:31  End

PodCast

Week of January 21, 2011

Related Blog

This week’s topics include use of an antidepressant to manage hot flashes, the natural history of coronary artery disease, a new imaging technique for diagnosin
g Alzheimer’s disease, and storytelling to improve blood pressure control.
 
Program notes:

0:27    Storytelling and blood pressure control
1:30    They picked a high risk population
2:36    Don’t know the mechanism
3:39    An SSRI for treatment of hot flashes
4:28    Decreased by 50%
5:30    Treat for as short a period as possible
6:03    PET imaging for detecting Alzheimer’s disease
7:02    Do we need a test since there are no interventions?7:52  Natural history of coronary artery disease
8:53    Didn’t predict troublesome
blockages ahead of time
10:02   End

PodCast

Week of January 14, 2011

Related Blog

This week’s topics include treating middle ear infections in kids, a new way to test for Down syndrome, two medications for initial treatment of high blood pressure, and a lack of evidence for ‘expert’ recommendations.

Program notes:

0:24  Polypharmacy for high blood pressure
1:19  300 patients got either two medications right away or one of the two
2:14  Too much decrease in blood pressure?
2:49  Maternal blood test to detect Down’s
3:41  Amniocentesis risk
4:38  If used as routine screen
5:27  Treatment of otitis media or middle ear infection
6:22  Antibiotic or not?
7:20  Complications related to untreated infection
8:01  Expert guidelines basis
9:01  No single study will apply to all patients
10:09 End

PodCast

Week of January 11, 2011

Related Blog

This week’s topics include treatment of mild congestive heart failure, who is getting implanted defibrillators, antibiotic treatment for irritable bowel syndrome, and walking assessment for elderly.

Program notes:

0:30  Treatment of early congestive heart failure
1:20  In the past beta blockers and ACE inhibitors
2:03  Aldosterone inhibitor added
3:02  How hard is it for patients to follow this regimen?
3:48  Potentially inappropriate placement of defibrillators
4:31  About 20% had them placed when not indicated
5:30  Assessment of walking and survival in elderly
6:32  This might be called a new vital sign
7:04  Potential treatment for irritable bowel syndrome
8:02  Improvement in those who received antibiotic
9:01  Do patients need to be treated repetitively or for longer periods of time?
10:08 End

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