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Johns Hopkins Medicine PodMed Archives - 2008

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PodMed is a weekly podcast looking at the top medical stories of the week for people who want to become informed participants in their own health care. With Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine, and Rick Lange M.D., professor of medicine at Johns Hopkins and vice chairman of medicine at the University of Texas Health Science Center at San Antonio.

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podcastWeek of December 26, 2008This week’s topics include genetic variations related to blood thinning efficacy, pediatric anxiety disorder treatment, use of medications among elderly, and sleep and coronary artery calcification.

Program notes:

0:20  Clopidogrel and genetic variation
1:10   Inhibit platelet clumping
2:10   As much as thirty percent of population has this
3:00   Sleep and coronary artery calcification
4:15   Suggests that shortened sleep is a risk factor
5:01   Sleep reduction associated with multiple negative effects
5:26   Older adults largest consumers of prescription medications
6:07  Patients need to make physicians aware of medications they’re taking
7:00   Best treatment for pediatric anxiety disorders
8:05   No therapy only about 25% improvement
9:05   No increase risk of suicide attempts or ideation
10:26 End

podcastWeek of December 19, 2008This week’s topics include doctors and the truth, missing colon tumors with colonoscopy, single dose steroids for preterm labor, and low glycemic diets.

Program notes:

0:21   Colonoscopy misses right side tumors
1:19   Cancers on left side prevents about 70%
2:25   Why aren’t right side tumors detected?
3:01   Benefits of low glycemic diet in diabetes
4:02   Lower sugar and higher HDL cholesterol
5:03   It is wise to adopt this diet
5:23   Not favorable effect of multiple steroid doses in preterm labor
6:27   Steroids arrest growth
7:00   Family member assessment of doctors
8:00   Physicians have been reluctant to provide specific prognostic information
9:00    Share your decision making process
10:02  Want honest and truthful physicians
10:26   End

podcastWeek of December 12, 2008This week’s topics include flu awareness week, no benefit from antioxidants in preventing cancer in men, unintentional overdoses with prescription drugs, and eye diseases increase worldwide.

Program notes:

0:25 Influenza review in NEJM
1:35 Expanded vaccination guidelines
2:23 Vaccine developed before the flu season
3:21 Flu mist
4:19 JAMA study panning C, E, and selenium
5:16 Antioxidants don’t seem to help
5:28 Unintentional overdose from prescription medications
6:22 Got it from people to whom it was prescribed
7:05 Increase in eye disease
8:12 Diabetics need regular eye exams
9:22 Collect reading glasses for worldwide distribution
9:47 End

podcastWeek of December 5, 2008This week’s topics include mental illness among college students, potential utility of an old medication for advanced Alzheimer’s, comparison of generic versus brand name medications, and medications to treat high blood pressure.

Program notes:

0:22 College students and mental illness
1:18 Alcohol use and dependence
2:06 Few sought treatment
3:27 Generic versus brand name medications
4:13 For most of the drugs examined no difference
5:11 FDA approved bioequivalent drugs
5:26 Hypertension treatment
6:25 More expensive drugs under patent
7:30 Try a single medication for several weeks
8:40 Diuretics may drop potassium too low
9:06 Drug for use in advanced Alzheimer’s
10:34 End

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podcastWeek of November 28, 2008This week's topics include new migraine treatment, CT for assessing heart disease, testing everyone for HIV, and steroids and COPD.
Program notes:

0:35    CT assessment of heart's arteries
1:23    Can see to about half a millimeter
2:14    Low risk populations
3:15    Should not be a routine screening device
4:10    Used inhaled steroids in people with COPD
5:12    A worldwide problem
5:43    Everyone should be screened for HIV
6:38    20,000 transmission due to people who don't know they're infected
7:22    New medication for migraines
8:23    Doesn't have same side effects
9:16    Phase III trial
9:51    End

podcastWeek of November 21, 2008This week’s topics include adult vaccination, no benefit from gingko, Meniere’s disease, and antidepressant use.

Program notes:

0:30   Room spinning around
1:18   Thousands affected by Meniere’s disease
2:08   If we can manage people medically most people improve
3:08   Use of gingko for prevention of Alzheimer’s
4:07   No reduction in incidence or progression
5:03   Tell your physician about supplements you may be taking
6:02   Adults need routine vaccination
7:12   Important to realize indications
8:10   Clinical practice guideline for depression medications
9:10   Continue treatment for some time
10:24 End

podcastWeek of November 14, 2008This week’s topics include reducing C-reactive protein with a statin, short sleep duration and cardiovascular events, abdominal and body fat and heart disease, and fasting triglycerides.

Program notes:

0:21    This week it’s all about the heart
1:03    Almost 400,000 people with fat assessments
2:00    Fat cells are an endocrine organ
3:02    Waist circumference to assess
3:38    Use of statins in people with elevated C-reactive protein
4:30   Absolute risk incredibly small
5:30   People on statins had higher incidence of diabetes
6:13   Non-fasting triglycerides
7:11   If doctor wants blood drawn at a certain time
7:25   Short sleep duration predictor of cardiovascular events
8:20   400% increased risk of event
9:23   Ambulatory blood pressure monitor
10:30 End

podcastWeek of November 7, 2008This week’s topics include HPV infection detection and possible vaccination of boys, the role of homocysteine, physician prescribing of placebos, and chronic medication use in children.

Program notes:

0:21   BMJ study on physician prescription of placebos
1:19   Placebos can be inert or active
2:23   Have prescribed placebos
3:03   Alarming increase in medication use in kids
4:57   Use of HPV vaccine in boys
6:34   Oral rinse can detect
7:20   If the incidence was higher we would do
7:36   Two studies on homocysteine
8:00   Homocysteine and depression
9:00   Whether treatment affects disease
10:01  Lowering homocysteine doesn’t help
10:25  End

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podcastWeek of October 31, 2008This week’s topics include statins and pneumonia, pneumovax in smokers, the role of c-reactive protein and a potential new obesity drug.

Program notes:

0:25    Potential drug for obesity
1:22    What’s different is people lose twice as much weight
2:24   Originally developed for Alzheimer’s
3:15   Pneumonia and statins
4:13   Had to take at time of admission
4:52   C-reactive protein
5:49   Increased risk for cardiovascular disease?
6:50   Knowing about genetic makeup influences therapy
7:14   Vaccination against pneumococcal pneumonia
8:14   Flu pandemic and pneumonia
9:07   Seldom see in young individuals
9:46   End

podcastWeek of October 24, 2008This week's topics include suicide data, strategies to increase breast feeding, no aspirin benefit in people with diabetes, and harmful pharmacy practices. 

0:22   Middle aged women committing suicide
1:18   Targeted prevention programs not available
2:19   Possible explanations include depression
3:18   Increase rates of breast feeding if possible
4:16   Contacting women before and after delivery
5:15   Something for women to at least consider
5:39   Lack of benefit from aspirin
6:19   Aspirin effective in secondary prevention
7:23   Pharmacy practices harmful
8:15   Preauthorization such a hassle
9:03   Pharmacy costs rising dramatically
10:01 On the phone for hours
10:33 End
podcastWeek of October 17, 2008This week’s topics include an update on Vioxx, smoking cessation, macular degeneration risk factors, and
alcohol and brain volume.

Program notes:

0:25 Macular degeneration
1:23 Evaluated for the presence of macular degeneration
2:20 Healthy lifestyle and proper nutrition
2:55 Alcohol consumption and brain volume
3:50 Excessive intake accelerates
4:48 Studies would suggest that low alcohol intake may help
5:01 Smoking cessation
6:04 Programs in hospital setting
7:01 Has to be sustained effort
7:50 Vioxx update
8:50 Percentage increase versus number
9:32 Convinced of both things
10:33 End

podcastWeek of October 10, 2008This week's topics include the role of vitamin D in Alzheimer’s management, controversy regarding stents, management of atrial fibrillation and thyroid complications.

Program notes:

0:21 Role of vitamin D in Alzheimer’s management
1:23 Vitamin supplements in food
2:30 Elderly may be vitamin deficient
3:00 4000 people with diabetes
4:02 Blood pressure control also helped but didn’t persist
5:06 Have to keep blood pressure medications
5:18 Stress testing and stent placement
6:19 Controversy regarding stents
7:15 Stress testing available everywhere
7:45 Management of atrial fibrillation
8:42 Should medication be used long term or intermittently?
9:31 Thyroid complications
10:03 End

podcastWeek of October 3, 2008This week's topics include a new class of HIV medications, tight glucose monitoring in diabetes, depression and heart disease, and single-reader mammography.

Program notes:

0:25      Single reader mammography
1:28      Cancer detection rate similar with both
2:27      How much experience does this person have?
2:50      Continuous glucose monitoring
3:50      Needle sensor placed under skin
4:49      Not difficult to use the sensor
5:43      For adolescents less important to monitor
6:06      Depression and heart attacks
7:12      Two questions to screen
8:20      Treatment with better outcome?
8:45      New medications for HIV
9:31      Could use for prevention?
10:15    End

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podcastWeek of September 26, 2008This week's topics include the risk of some inhaled medications, new information on CPR, colon polyps in blacks, and expanded use of a medication used in many strokes.

Program notes:

0:27   CPR information
1:18   Difference in survival after CPR around North America
2:06   Everybody needs to be aware of how to do CPR
3:07   Shouldn't transport if its futile
4:03   Realistic about what CPR can accomplish
4:30   Clot busting agents in stroke
5:18   Benefits clearly outweighed the risks
6:15   Only about 4% get this agent
6:33   Colon polyps in African Americans
7:13   Race matters
8:00   Inhaled medications and heart attacks
9:02   Meta-analysis suggests increased risk
10:05 End

podcastWeek of September 19, 2008

Program notes:

0:23    BPA in plastics
1:25    Leach from plastic into food
2:27    More data there are concerns
3:19    Screening colonoscopy
4:22    Detection of polyps
5:37    Flat polyps
6:13    Negative test doesn't need yearly repeat
6:56    Flu vaccine in pregnant women
7:26    Infants at high risk for flu
8:08    Use of antibiotics in preterm labor
9:17    Premature labor but no active infection
10:25  End

podcastWeek of September 12, 2008This week's topics include an obesity-related protein, prevention and control of influenza, measles update, and HIV testing.

Program Notes:

0:33 Brain derived neurotrophic factor
1:41 Have a specific abnormality helped identify
2:30 Help target specific therapies
3:30 Measles update
4:25 Most children who attend public schools are vaccinated
5:25 Get children vaccinated
5:39 Updated flu vaccination guidelines
6:22 Older people don't respond very well
7:20 In terms of cost effectiveness
7:35 CDC changes HIV testing
8:23 Objections to HIV testing?
9:20 Effective treatment exists
9:46 End

podcastWeek of September 5, 2008High blood pressure in kids, nuts and guts, glucose control in critically ill, and contaminants in ayurvedic medicines.

Program notes:

0:32 Consumption of nuts and diverticular disease
1:30 What contributes to it?
2:30 Benefit of nuts in the diet
3:05 Ayurvedic medicines and metals
4:10 Levels very high
5:00 Make your physician aware you're taking them
6:00 Allopurinol and high blood pressure in kids
7:00 Understand the mechanism
8:01 Glucose control in critically ill
9:03 Meta-analysis of many studies
10:31 End

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podcastWeek of August 29, 2008This week's topics include chewing gum after bowel surgery, statins and myopathy, recovery from West Nile infection, and preeclampsia and kidney disease.

Program notes:

0:24   Chewing gum and bowel surgery
1:25   Nurses giving chewing gum
2:28   Saves a lot of money
2:52   Preeclampsia and kidney failure
3:50   Kidney compromise five or more years later
4:44   Common causative agent
5:09   West Nile virus recovery
6:10   Recovery usually complete
6:55   Statins and myopathy
7:44   Gene responsible for 60%
9:07   End

podcastWeek of August 22, 2008This week's topics include role of vitamin B in cardiovascular disease, cautions on HPV vaccine use, new treatment for cystic fibrosis and diabetes and arsenic.

Program notes:

0:30     Cystic fibrosis treatment
1:30     Truncated protein defect
2:24     Personalized medicine
3:13     HPV vaccination implications
4:15     Use of vaccine at particular ages
5:17     How and to whom to administer vaccine
5:37     B vitamins and heart disease
6:27     Supplementation doesn't help
7:05     Arsenic exposure in water and type 2 diabetes
8:07     Inorganic form deleterious
9:02     Attack at level of water supply
10:23   End

podcastWeek of August 15, 2008This week's topics include physical activity in immigrant children, psychotherapy trends in the US, one benefit of estrogen therapy, and prostate cancer screening in older men.

Program notes:

0: 20    Estrogen therapy benefit
1:22     Estrogen affects different pathways in the brain
2:15     Less psychotherapy taking place
3:16     Benefits of CBT in managing mental illness
4:28     Need better reimbursement
4:40     Don't screen older men for prostate cancer
5:33     No benefit in screening in men with less than 10 years to live
6:24     Men over the age of 75
7:21     Problem with patients accepting this change
7:50     Lack of physical activity in immigrant children
8:46     Children with least access to medical care
9:37     End

podcastWeek of August 8, 2008This week's topics include HIV incidence, treatment of TB and HIV, the success of smoke-free environments, and H. pylori infection and stomach cancer.

Program notes:

0: 21    True incidence of HIV infection in US
1:31     10% over the age of 50
2:45     High risk populations should be tested
3:30     People with HIV infection at risk for TB
4:30     Multiple medications interact
5:08     Smoke free environment in Scotland
6:12     Smoking increases risk for blood clots
7:00     H. pylori infection and stomach cancer
8:09     Eradicating H. pylori decreases recurrence
9:00     Screening and eradication in high risk folks
10:10   End

podcastWeek of August 1, 2008This week's topics include AIDS in Latinos, a new anti-HIV medication, TB and TB and HIV infection, and tattoo removal.

0:45   Latino background and AIDS
1:50   Why are they developing AIDS more often?
2:41   Need cultural sensitivity to Latinos
3:30   Inhibition of a different enzyme
4:30   Become infected with TB and it becomes latent
5:27   High risk groups need screening
6:27   HAART really helps
7:02   Motivation for tattoo removal
8:05   20% of individuals want it removed
9:00   Negative societal connotations
10:24 End

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podcastWeek of July 25, 2008This week's topics include sildenafil use in women, a new drug for liver cancer, a method for determining whether chemotherapy is likely to be useful in lung cancer, and the salmonella outbreak.

Program notes:

0:30 Salmonella outbreak
1:29 Tomatoes initially implicated
2:20 Perishable food not around anymore
3:23 All utensils washed with water and soap
3:50 Sildenafil in women
4:24 Sexual dysfunction triggers stopping depression medication
4:50 Finding tumor cells in blood in lung cancer
6:08 Predicts who will respond to chemotherapy
7:08 New treatment for liver cancer
8:08 Increasing incidence of liver cancer worldwide
9:07 Effective screens for liver cancer?
10:01 End

podcastWeek of July 18, 2008This week's topics include lack of exercise among teens, a vaccine and antihistamine against Alzheimer's, companions' role in physician visits, and falls and joint replacement in elderly.

0:30   Teenagers' lack of exercise
1:36   What issues account for that?
2:28   Now schools recommending activity
3:25   Two studies looking at treatment of Alzheimer's disease
4:24   Targeting amyloid didn't help
5:27   Older folks with a companion have better outcomes
6:20   More the companion contributes the better
7:14   Routine education about fall avoidance
8:22   Things around the house to avoid falls
9:15    Knee and hip replacement helps those aged 75 and older
10:08  End

podcastWeek of July 11, 2008This week's topics include food diaries, use of hormone therapy in men with early prostate cancer, testing cholesterol in children, and the ankle brachial index.

0:30    Cholesterol measurement in children
1:30     Children before 10 but after 2 get screened
2:25     Decrease obesity, manage high blood pressure
3:16     Lifestyle modification
3:24     Food diaries to maintain weight loss
4:25     45% African Americans
5:03     Ankle brachial index
6:15     If index is abnormal risk is raised 300%
7:06     Use of androgen deprivation therapy in early prostate cancer
8:05     Trying to use in early stage disease
9:02     Side effects in 10-50% of patients
10:13    End

podcastWeek of July 4, 2008This week's topics include an HIV update, whether aggressive treatment benefits one heart condition, a new type of agent for treating thyroid cancer, and depression in cancer patients.

Program notes:

0:30    Vice chairman of medicine
1:16    MMWR shows increase in diagnosis of HIV
2:18     You can get infected fairly easily
3:17     Side effects of therapy
4:15     Cancer patients with depression
5:09      About 65% on antidepressant
6:00      Acute coronary syndrome or possible heart attack
7:26      Differences between men and women
8:14      Thyroid cancer treatment
9:17      Prevents new blood vessel formation
10:31    End

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podcastWeek of June 27, 2008This week's topics include statin sale OTC, electronic patient records, one number for blood pressure, and a skin patch for traveler's diarrhea.

Program notes:

0:40   One blood pressure number
1:30   As we age the upper number goes up
2:14   Systolic number most important
3:14   Phase two trial for skin patch vaccine
4:00   Sounding board on OTC sale of statins
5:04   Statins may have broad impact
6:10   Available anywhere OTC?
7:00   Electronic health records available to physicians and consumers
8:20   Google and Microsoft testing
9:03   Privacy is major issue
10:36  End

podcastWeek of June 20, 2008

New hope for lung cancer, treating arrhythmias, association with diabetes and depression, and no new medications for heart failure 

Program notes:

0:30   Bidirectional association with diabetes and depression
1:33   Diabetes may predispose to depression
2:31   Patients and physicians need to look for both
3:30   May cause harm in heart failure
4:27   Use devices instead of medications
5:12   Medicines are useful too
6:00   Great interest in restoring heart rhythm
7:00   Ablation therapy possible
8:00   Lung cancer ablation
9:05   Successful in 99% of individuals
10:14 End

podcastWeek of June 13, 2008

This week's topics include vitamin D and heart attacks in men, lack of cardiovascular benefit of tight blood sugar control, avoiding macular degeneration, and a new way to make flu vaccine.

Program notes:
0:30
Macular degeneration
1:30 Don't recognize gradual loss of vision
2:35 Prevent new blood vessel formation
3:10 Reduced death with fish oil ingestion
4:05 Tight blood sugar control in diabetes and death
5:17 Probably not just simple diabetes
6:29 Use hemoglobin A1c
7:30 Avoid egg allergy with flu vaccine
8:00 Vitamin D and heart attacks in men
9:00 Vitamin D easily assessed
9:51 End
podcastWeek of June 6, 2008

This week's topics include patient perceptions of mortality with heart failure, a potential new treatment of heart attacks, managing nausea related to chemotherapy, and preventing kidney failure in people with diabetes.

Program notes:
0:23
   May be a new treatment in heart attack
1:20   Clot occludes blood flow
2:22   Both are invasive techniques
3:00   Review article of nausea and chemotherapy
4:07   Newer agents are not sedating
5:00   Assessed people's perception of life expectancy
6:13   Don't consider invasive therapies
7:04   Patient participation important
7:44   Diabetes and kidney failure
8:18   Look for albumin in urine
9:03   Evaluation of kidneys every year
10:01 End
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podcastWeek of May 30, 2008

This week's topics include obesity in kids, use of home blood pressure monitors, interventions in type 2 diabetes, and gum disease and cancer.

Program notes:

0:30   Increasing obesity in adolescents
1:26   About a third are significantly overweight
2:10   Use insulin early in type 2 diabetes
3:17   Sets the tone for a new type of therapy
4:19   17% reduction in cardiovascular disease
5:19   Home monitoring of blood pressure
6:37   Take machine into doctor's office
7:26   Record throughout the day and the time
8:14   Gum disease and cancer
9:28   14% increased risk
10:13 Does treatment decrease risk?
10:51 End

podcastWeek of May 23, 2008

This week's topics include a new type of LDL, under the tongue allergy treatment, risks of the metabolic syndrome, and treatment of H. pylori infection.

Program notes:
0:31   Helicobacter pylori
1:30   Effective eradication important
2:21   Should screening be done?
3:04   Millions have allergies
4:11   Mix of allergens under the tongue
5:12   A very promising therapy
6:14   Oxidized LDL important in atherosclerosis
7:30   Useful as a predictor
8:17   40% of people have metabolic syndrome
9:06   Does metabolic syndrome mean anything?
9:49   Lifestyle modification important
10:47 End

podcastWeek of May 16, 2008

This week's topics include beta blockers and non-heart surgery, carotid sounds, smoking interventions by peers, and monoclonal antibody treatment of psoriasis.

Program notes:
0:31 Beta blockers prior to surgery
1:18 Surgery increases heart rate and blood pressure
2:14 May be too much beta blocker too soon
3:06 Noise in carotid arteries
4:12 Treat patients more aggressively
5:09 Peer intervention and smoking prevention
6:42 Reduces rate of smoking
7:02 Psoriasis treatment
8:02 Struggle to develop a treatment
9:04 Monoclonal antibody can be extremely effective
10:02 Antibody binds to a protein involved in disease
11:00 End

podcastWeek of May 9, 2008

This week's topics include the fit versus fat controversy, osteoporosis genes, blood substitutes, and effects of hormone replacement therapy in women.

Program notes:
0:30   Women who are fit don't lose risk of fat
1:20   BMI measure
2:15   No substitute for weight loss
2:36   Blood substitutes
3:10   Increases risk of death and heart attacks
4:23   Animal models substantiate
5:00   Burden of osteoporosis
6:01   Combination of bone density decrease and genes
7:05   Can tie the genes to bone degradation
8:10   Hormone replacement therapy
9:06   Confirms increased risk of stroke and related to dose
10:01 Need to weigh the risks and benefits
10:45 End

podcastWeek of May 2, 2008

This week's topics include high blood pressure and kidney disease in African Americans, possible negative side effects of drugs to treat osteoporosis, a potential new treatment for Alzheimer's disease.

0:30   New treatment for Alzheimer's disease
1:18   Decreased cognitive defects with mild dementia
2:08   Common medication for osteoporosis
3:03   Atrial fibrillation
4:06   Identified with once yearly injection
5:08   Glitazones to treat oral diabetes
6:02   Substantial number of people use them
7:05   Controlling blood pressure and kidney disease
8:08   Kidney function declined by a high percentage
9:06   Race specific identifiers?
10:41 End

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podcastWeek of April 25, 2008

This week's topics include a new test for fertility, mammography in women older than 80, heart risk and ADHD medications, and the heparin debacle.

Program notes:

0:20    Fertility testing
1:19    Anti-mullerian hormone
2:10    May be the most predictive test
3:04    Does mammography help women aged 80 and older?
4:15    Average life expectancy mid-eighties for women
5:01    ADHD medications and heart risk
6:07    Primary care docs must assess
7:15    We want to be aware of risks and benefits
8:00    Heparin and its risks
9:00    Chemical similar to heparin
10:02   Rely too much on FDA
11:06   End

podcastWeek of April 18, 2008

This week's topics include paired kidney transplants, mumps infections in the US, waist size and disease and death, and fish oils in Crohn's disease.

0:33    Paired kidney transplant
1:10    Large databases help match
2:16    Should have recognized this idea
3:06    Successful at living with just one kidney
4:00    Mumps coming back in US?
5:02    Two immunizations may not be adequate
6:07    Overseas travel may result in exposure
7:01    Waist size significantly affects mortality
8:00    Address as a separate risk factor
9:00    Fish oils and Crohn's disease
10:0    Prevention not effective
11:00   No proven dietary interventions
11:22   End

podcastWeek of April 11, 2008

This week's topics include the best treatment for carotid artery blockage, son to father transmission of bird flu, increase in esophageal cancer, and teens with TVs in their rooms.

Program notes:

0:30    Son to father transmission of bird flu
1:22    May be a flu that's easily transmitted
2:21    Passive immunization
3:16    Human to human transmission
4:42    Addressed adolescents
5:28    Esophageal cancer increase
6:24    OTC heartburn medications
7:25    Burn away lining of esophagus
8:00    Carotid stenosis
9:01    Stent or surgery?
10:17   How long does it last?
11:08   Blockage in carotids
12:44   End

podcastWeek of April 4, 2008

This week's topics include AEDs in homes, compression only CPR, treatment of high blood pressure in older folks, and HPV testing in women with normal Pap smears.

Program notes:

0:30    AEDs in homes
1:32    Distributed widely in public places
2:38    High risk folks perhaps internal defibrillator
3:00    Compression only CPR
4:02    Treatment of high blood pressure in older folks
5:04    20% decreased risk of death
6:01    2/3 required additional medicine
7:07    HPV testing in women with normal Pap smears
8:08    All women got HPV screening
9:15    Test isn't type specific
10:20  Women may question why do it at all
11:30  End

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podcastWeek of March 28, 2008

This week's topics include dangers of mechanical ventilation, predictive value of coronary calcium scanning, risks of hair dyes, and kidney function compromise from colonoscopy preparation.

Program notes:

0:30    Occupational hazards related to hair dyes
1:32    Hairdressers have increased risk of cancer
2:24    Coronary calcium scanning
3:23    Increased risk of heart attack
4:42    Screening?
5:30    Preparation for colonoscopy
6:25    Oral phosphate solution compromises kidneys
7:42    Avoid if kidneys are compromised
8:20    Effects of ventilation on diaphragm
9:23    Causes problems with diaphragm anatomy and function
10:56   End

podcastWeek of March 21, 2008

This week's topics include the benefits of clinical trials, receiving care at a teaching hospital, satisfaction after treatment for prostate cancer, and the effects of using old blood.

Program notes:

0:25      Transfusing old red blood cells
1:30      Compared old with new red blood cells
2:35      Other complications of transfusions
3:30      May not apply to all types of surgery
4:02      Family and patient satisfaction after prostate cancer treatment
5:15      Affect quality of life
6:22      Quality of life issues related to cancer treatment
7:17      Clinical trials on cancer
8:18      Randomizing allows comparison
9:10      Outcomes in hospitals that engage in clinical trials
10:06      Patients receive standard of care
11:04     Most important to get to closest hospital
12:49      End

podcastWeek of March 14, 2008

This week's topics include management of urinary incontinence in women, dangers of strangulation games in teenagers, depression and testosterone, and screening for MRSA.

Program notes:

0:37    Testosterone and depression
1:42    Are other health issues factored out?
2:32    No long term randomized data on testosterone supplements
3:25    Prevalent choking game
4:19    Self induced may result in death
5:08    MRSA and screening
6:15    Just testing high risk patients expensive
7:09    Urinary incontinence in women
8:14    Stress vs. urge incontinence
9:18    Pelvic exercises
10:10  May need surgery
11:02  End

podcastWeek of March 7, 2008

This week's topics include modifying TV and computer use by kids, best place to have lung surgery, risks of hormone replacement therapy, and a blood pressure vaccine.

0:19 Benefits of reducing TV and computers
0:56 Impact on very young children
1:40 Children lost weight
2:44 Make suggestion that TV is cue for eating
3:24 Parents calories change too
4:04 Fears of teaching hospitals
5:00 Most have access to teaching hospitals
6:00 Risks and benefits of hormone replacement therapy
7:01 Reserved for women with severe symptoms
8:04 If symptoms are not severe or debilitation, wait
9:03 Immunization against angiotensin II
10:05 Many people can't or won't take medication
11:01 Angiotensin modification and blood pressure
11:52 End

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podcastWeek of February 29, 2008

This week's topics include risks of anemia drugs, treating depression in kids, the flu vaccine for children, and an approach to keep elderly people in their homes.

Program notes:
0:28      review of interventions for keeping older folks at home
1:02      number of interventions for assessment and treatment
2:06      multidisciplinary evaluation
3:09      who's giving their medications
4:10      prevented serious problems for elderly
4:20      CDC recommendations that kids get flu shot
5:26     children between 5 and 18 more likely to get flu
6:35     will everyone get the flu vaccine eventually?
7:27     many children don't respond to depression treatment
8:34     individuals who received different medication plus therapy responded
9:40     use of anemia medications
10:35   drugs used to treat cancer suppress red blood cell production
11:20   people with very low red blood cell count may benefit
12:21   End

podcastWeek of February 22, 2008

This week's topics include the best treatment for just diagnosed Crohn's disease, FDA and Supreme Court activity affecting healthcare, post-stroke treatment, and surgery for spinal stenosis.

Program notes:
0:22     FDA has played a role in off label use
1:23     When stents were approved they were for certain indications
2:23     Initial studies it is off label but needs to be studied
3:29     If FDA has approved states can't override
4:29     Appropriate treatment of newly diagnosed Crohn's
5:30     Use of monoclonal antibody
6:17     Key to this study is early use
7:06     Spinal stenosis results from disk bulging
8:21     Unusual to have spinal stenosis in younger people
9:09     Symptoms of stroke
10:12   In the past clot dissolving agents restricted to short window
11:10   If patient has an ischemic penumbra
11:56   End

podcastWeek of February 15, 2008

This week's topics include longevity in older men, obesity and cancer, blood pressure management, and use of probiotics in pancreatitis.

0:20     Longevity in older men
1:14     Started with doctors older than 70
2:15     A lot of this within our control
3:05     Obesity and cancer risk
4:12     70% of men and 60% of women
5:09     BMI 25 or more
6:02     Dietary modifications and blood pressure
7:01     Blood pressure medication issues
8:07     Not all medications cause side effects
9:07     Not just obese have high blood pressure
9:45     Probiotics
10:14   Pancreatitis may respond
11:10   Over the counter supplements need testing
11:33    End

podcastWeek of February 8, 2008

This week's topics include marijuana and your teeth, re-blockage of neck arteries, genetic testing to predict drug allergy, and control of diabetes.

0:30     Periodontal disease
1:22     Marijuana smoking associated with periodontal disease
2:20     Even with other confounders risk rises
3:16     Aggressive management of type 2 diabetes
4:11     Multifactorial intervention improves survival
5:30     Carotid endarterectomy
6:20     Procedures not necessarily curative
6:52     Pharmacogenetics or pharmacogenomics
7:52     Group with testing avoided allergic reactions
8:42     Can identify genetic basis
9:56     End

podcastWeek of February 1, 2008

This week's topics include where to have a heart transplant, effects of aging, risks of being a sports fan, and treatment for aortic aneurysm.

0:15      Sports observer
1:02      Just when the German teams played
2:08      Men more than women
3:10      Where you should have a heart transplant
4:12      3000 people on heart waiting list
5:13      Most of the centers that do high volume
6:01      Abdominal aortic aneurysm
7:14      Okay to watch an aneurysm
8:05      Aging and diabetes
8:25      Telomeres
9:10       Exercise and telomere length
10:07     Exercise and anti-aging effect
11:04     Compared elderly diabetics with non-diabetics
12:00    Need to look for chronic diseases
12:28    End

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podcastWeek of January 25, 2008

This week's topics include combination cholesterol lowering medications, fitness as a predictor of heart-related death, gastric banding and diabetes, and oral contraceptives and the risk of ovarian cancer.

0:26      Vitorin and cholesterol lowering medications
1:26      Thickening of arteries
2:18      Expense of combination
3:06      Can lower risk of death in infections
3:42      Level of fitness determines cardiovascular mortality
4:51      Men who were highly fit
5:09      Gastric bypass and obesity
6:32      Remind of types of surgery
7:30      Risk associated small
8:30      Reduction in weight produces remission
9:04      American Heart Association goal
10:23    Oral contraceptives and reduction in ovarian cancer risk
11:13    Protective benefit persists up to 30 years
12:30    End

podcastWeek of January 18, 2008

This week's topics include modifying the immune response in congestive heart failure, testosterone supplements in men, palliative care guidelines, and which studies get published.

0:30      Inflammation in congestive heart failure
1:30      Can't find any other cause for the condition
2:30      Has to be given early
3:30      Testosterone supplements
4:35      Benefits mixed
5:33      Use of testosterone does not improve cognition
6:11      Which studies get published
6:49      94% of positive studies published
7:56      Need to interpret the larger picture
8:15      Palliative care
9:06      85% of healthcare dollars spent in last few weeks of life
10:13    Address early advance directives
11:22    Realistic expectations
12:58    End

podcastWeek of January 11, 2008This week's topics include FDA warning on osteoporosis drugs, vitamin D and heart disease, childhood allergies, and avoiding weight gain with antipsychotic medications.

0:29      FDA warning on bisphosphonates
1:23      Use of these medications increased
2:26      Alert their doctor to symptoms
3:00      Supplements with calcium/vitamin D
4:26      Supplements of vitamin D good?
5:30      Childhood allergic diseases
6:32      Maternal diet not a factor
7:40      Non-whole cow's milk formula
8:21      Weight gain with antipsychotic medications
9:23       Lowered weight by 7%
10:24     Older folks with behavioral issues
11:21      End

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