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There are three observational cohort studies:
- CHARTER: Central Nervous System HIV Antiretroviral Therapy Effects Research
- Sleep Study
- Clinical Outcomes Core - Center for novel therapeutics for HIV-associated cognitive disorders
Purpose: To evaluate the effects of ARV therapy and HIV on the CNS through medical and behavioral assessments.
NOTE: Closed for enrollment; staff will contact patients for follow-up.
Some scientists have found that in some HIV positive individuals normal sleep and wake cycles are disrupted. It is possible that this disruption is further complicated by medications used to manage the HIV virus as well as by other body conditions such as peripheral neuropathy. An upcoming study at Johns Hopkins University led by Dr. Charlene Gamaldo will try to understand further what sleep complications may be related to HIV infection and how peripheral neuropathy affects sleep in people with HIV.
NOTE: Study is currently closed for enrollment.
The major goal of this Clinical Outcomes Core is to validate new outcome measures for epidemiological research and treatment trials and to provide the statistical and data management support for studies involving the Center grant resources.