The Johns Hopkins Hospital
Department of Neurology
Rangos Bldg, Room 248
855 N. Wolfe Street
Baltimore, MD 21205
Dr. Lyle Ostrow received his M.D. degree and a Ph.D. in Biophysics from the State University of New York at Buffalo. He completed an Internal Medicine Internship at Johns Hopkins Bayview Medical Center, followed by Neurology Residency training at The Johns Hopkins Hospital. After residency, Dr. Ostrow completed a fellowship in Neuromuscular Medicine also at Johns Hopkins.
Now an Assistant Professor in the Department of Neurology, Dr. Ostrow sees patients with a broad range of diseases of nerve and muscle, including amyotrophic lateral sclerosis (ALS), CIDP, peripheral neuropathies, muscular dystrophies and myopathies, myositis, and myasthenia gravis.
Dr. Ostrow’s laboratory research focuses on the role of astrocytes in amyotrophic lateral sclerosis (ALS) and other neurologic disorders. He is investigating whether abnormally increased production of a protein called endothelin by astrocytes may represent a novel therapeutic target in ALS. He also studies ways in which astrocytes sense and respond to mechanical stress, and how this may be involved in several neurologic diseases.
Dr. Ostrow sees outpatients on the 5th floor of the Johns Hopkins Outpatient Center on Tuesday mornings. He also performs outpatient nerve and muscle biopsies on Mondays and attends on the Inpatient Neurology service at the Johns Hopkins Hospital.
- American Board of Psychiatry and Neurology