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Clinical Trials

Currently Enrolling Research Studies in Movement Disorders

Your participation will allow you to have first hand experience with developing new medical treatments, which may be beneficial to many individuals in the future. The current methods that are used to treat neurologic disorders are available because of others who have volunteered their time and energy in the past. Clinical trial information is excerpted from www.clinicaltrials.gov.

TitleObjectiveEligibilityContact
Parkinson Progression Markers Initiative (PPMI) - Genetic CohortIdentify genetic links to PD and learn how the LRRK2 mutation affects certain populations of people. (Part of the Michael J.Fox Foundation Parkinson’s Progression Markers Initiative)1.) Individuals diagnosed with PD and are of Ashkenazi Jewish decent
2.) Individuals without PD who are of Ashkenazi Jewish decent AND have a first degree relative with PD. PI: Zoltan Mari, M.D. (NA_00039232)
Arita McCoy, R.N., B.S.N.
(410) 955-2954
National Parkinson Foundation Patient RegistryDevelop quality care standards for PDAll PD patients and carepartners
PI: Zoltan Mari, M.D. (NA_00036863)
Becky Dunlop, R.N., B.S.N.
(410) 955-8795

Bailey Vernon, M.P.H.
(410) 616-2811
Udall Center Longitudinal StudyExamine the relationship between the clinical symptoms of PD and the disease process in brain tissure (participation includes eventual brain donation)Individuals diagnosed with PD or atypical PD and those without a neurological diagnosis
Liana Rosenthall, M.D.
(NA_0032761)
Catherine Bakker (410) 616-2814
Udall Center Brain Donation ProgramExamine the pathological changes in the brain tissue of individuals diagnosed with PD or related disorders compared to controlsIndividuals diagnosed with PD or atypical PD and those without a neurological diagnosis
(NA_0032761)
Catherine Bakker (410) 616-2814
Adamas 302 (blinded) and 304 (placebo control)Determine safety and effectiveness of new extended release formulation of amantadine (amantadine HCL) to treat dyskinesiaIndividuals with PD who have untreated dyskinesia
Kelly Mills, MD (NA_00056431) (NA_00056432)
Becky Dunlop, R.N.
(410) 955-8795
MARK-PDFind biomarkers to improve diagnosis and treatment of people with PDIndividuals without PD
PI: Liana Rosenthal, M.D. (NA_00031749)
Nadine Yoritomo, R.N., B.S.N., C.C.R.P.
(410) 616-2822
Anxiety in Parkinson's One-day visit to assess anxiety symptoms in PDAll individuals diagnosed with PD
Gregory Pontone (NA_00092051)
Kate Perepezko
(410) 614-1242
Dystonia CoalitionDevelop better understanding of dystoniaAdults 18 and older with primary dystonia
PI: Zoltan Mari, M.D. (NA_00074297)
Becky Dunlop, R.N.
(410) 955-8795
Udall Center Longitudinal Study of Parkinson's Disease and Related DisordersExamine the relationship between the clinical symptoms of PD and the disease process in brain tissueAll individuals diagnosed with PD or atypical PD and those without a neurological diagnosis
PI: Liana Rosenthal, M.D. (NA_00032761)
Catherine Bakker (410) 616-2814
Transcranial Direct Current StimulationTest the therapeutic relevance of non-invasive brain stimulation for improving motor symptomsDiagnosed PD patients
PI: Reza Shadmehr, Ph.D. (NA_00081426)
Yousef Salimpour, Ph.D.
(410) 614-3424
MysticolInvestigate the efficacy of MYOBLOC (Botulinum toxin type B) injection in the treatment of sialorrhea (drooling or excessive salivation)Adults 18 and older with untreated excessive salivation in the last 3 months due to any cause
PI: Zoltan Mari, M.D. (NA_00084484)
Becky Dunlop, R.N.
(410) 955-8795
Cerebellar Hyperactivity in PDStudy how cerebellar hyperactivity influences gait and balance in individuals with PD with transcranial direct current stimulation

People with PD who have gait and balance difficulties
Amy Bastian, Ph.D. (IRB00052263)

 

Tjitske Boonstra (443) 923-2716
MRI PD StudyOne-day visit to explore the relationship between cognition and emotion in PDAll individuals diagnosed with PD
Gregory Pontone (NA_00087276)
Kate Perepezko
(410) 614-1242

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Maryland Patients

To request an appointment, please contact the Johns Hopkins Parkinson’s Disease and Movement Disorders Center at 410-502-0133.
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Adult Neurology: 410-955-9441
Pediatric Neurology: 410-955-4259
Adult Neurosurgery: 410-955-6406
Pediatric Neurosurgery: 410-955-7337

 

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