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Research

Division of Nephrology Research Interests

Glomerulonephritis

Glomerulonephritis is a group of kidney diseases characterized by inflammation of the filtering units of the kidney called glomeruli.  When inflamed these glomeruli allow passage of protein and blood into the urine.  Left untreated this chronic inflammation can lead to scarring, loss of kidney function, high blood pressure, and kidney failure requiring dialysis or transplantation.  Read more...

Polycystic Kidney Disease

Polycystic kidney disease (PKD) is a group of diseases characterized by dilatation of the tubular units of the kidney. The kidney tubules process the 140 liters of fluid filtered by the glomerulus into the final urine volume  (0.5-2.0 liters) that is made daily. Cystic tubules are unable to perform this function properly, resulting in fluid retention, high blood pressure and kidney failure requiring dialysis or transplantation.  Read more...

Retroperitoneal Fibrosis

Retroperitoneal fibrosis (RPF) is a rare condition characterized by the presence of inflammation and fibrosis in the retroperitoneal space.  The disease process typically begins with clinical symptoms of flank pain, and unexplained weight loss. Anatomically, inflammation and fibrosis start surrounding the large artery, called the aorta, that delivers blood from your heart to the rest of your body at the level just below your kidneys. This inflammation and fibrosis progresses inferiorly toward the arteries that carry blood to your legs, and outwards towards the kidney(s) and surrounding structures, ultimately leading to kidney failure.  Read more...

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