Equipment Overview

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Hitachi 7600 TEM operation

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Please refer to the Facility map for location of equipment.

Electron Microscopes
- Scanning Electron Microscope (SEM)
  - Leo/Zeiss Field Emission SEM (Why Field Emission is special...)
- Transmission Electron Microscopes (TEM)
  - Philips/FEI BioTwin CM120 TEM(best contrast images)
  - Hitachi 7600 TEM(speed and convenience; excellent images)
Fluorescence Laser Confocal Microscopes
- Multiphoton/SHG Laser Confocal Microscopes (best for live imaging/thick specimens)
  - Zeiss 710NLO Meta confocal microscope with tunable Coherent Chameleon Vision II laser (automated pulse-precompensation) -- the most advanced system from Zeiss and Coherent; amazing tissue/cell viability and tissue penetration; less noise/better signal
- Scanning-spot Laser Confocal Microscopes (best for 3D/4D images)
  - Zeiss LSM510 Meta confocal microscope (2 instruments within Facility)
    -- very popular; completely automated/easy-to-use; great for 3D/4D imaging; modules for FRAP and FRET and multi-position/multi-time-lapse image acquisition
- Laser Spinning-disk Confocal Microscopes (best for 3D/4D live-tissue and time-lapse studies)
  - 3i Marianis/Zeiss Live-cell Spinning Disk Confocal (fully automated with CO₂/humidity/temperature enclosure
  - 3i/Leica Spinning Disk Confocal (modular, fully automated; can customize all optics and perform microinjection)
Other Optical Microscopes (portable temperature-controlled specimen holders available)

Olympus IX81 -Fully automated filter wheels & motorized stage: ratio imaging & FRET
Zeiss Extended Time-lapse Live-cell -Fully automated microscope with double specimen chamber, ensuring stable live-cell culturing >2 weeks!

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