Gama, Lucio, M.S.

Lucio Gama, M.S.

Research Associate / Retrovirus Lab Manager
Email: lucio@jhmi.edu
Office: (410) 955-9770

BS, Biology (Genetics, Physiology, Biochemistry and Ecology)
Campinas State University, Campinas, SP – Brazil (1983-1986)
MS, Microbiology (Emphasis in Virology)
São Paulo State University, São Paulo, SP – Brazil (1989-1992)

Thesis: Comparative study of techniques for serological diagnosis in equine rhinopneumonitis.

Background:

Lucio Gama received his Master Degree in Virology in 1992 from the University of São Paulo, Brazil. For five years he taught Microbiology and Parasitology to second-year students at the Itajubá Medical School. From 1996 to 2001 he worked as a molecular biologist under the supervision of Dr. Gerda Breitwieser  in the Phisiology Department at the Johns Hopkins School of Medicine, studying the biological properties of the calcium receptor. Since September of 2001 he has been working as a laboratory manager for the Retrovirus Lab. In 2006 he became a Research Associate and started focusing his research on the innate immune aspects of SIV infection, especially the role of some pattern recognition receptors (PRPs) such as RIG-I and IPS-1.

Publications:

CLEMENTS, J.E., LI, M., GAMA, L., BULLOCK, B.T., CARRUTH, L.M., MANKOWSKI, J.L., ZINK, M.C. The central nervous system is a viral reservoir in simian immunodeficiency virus--infected macaques on combined antiretroviral therapy: a model for human immunodeficiency virus patients on highly active antiretroviral therapy. J. Neurovirol. 2005; 11:180-9.

BARBER, S.A., HERBST D.S., BULLOCK, B.T., GAMA, L., CLEMENTS, J.E. Innate immune responses and control of acute simian immunodeficiency virus replication in the central nervous system. J. Neurovirol. 2004; 10 Suppl 1:15-20.

MIEDLICH, S., GAMA, L., SEUWEN, K., WOLF, R.M.,  and BREITWIESER, G.E. Homology modeling of the transmembrane domain of the human calcium sensing receptor and localization of an allosteric binding site. J. Biol. Chem. 2004; 279:7254-63.

GAMA, L. and BREITWIESER, G.E. A carboxy terminal domain controls the cooperativity for extracellular Ca²⁺ activation of the human calcium sensing receptor. A study with receptor-green fluorescent protein fusions J. Biol. Chem.. 1998; 273: 29712-8.

GAMA, L. and BREITWIESER, G.E. Generation of epitope-tagged proteins by inverse PCR. Biotechniques. 1999; 26: 814-5.