Skip Navigation
 
 
 
 
 
Print This Page
Share this page: More
 

Retrovirus Lab : Recent Publications

The last ten most recent publications for each of our faculty is presented. 

Dr. Janice Clements

  1. Witwer, K.W., et al., Relationships of PBMC microRNA expression, plasma viral load, and CD4+ T-cell count in HIV-1-infected elite suppressors and viremic patients. Retrovirology, 2012. 9: p. 5.
  2. Zaritsky, L.A., L. Gama, and J.E. Clements, Canonical type I IFN signaling in simian immunodeficiency virus-infected macrophages is disrupted by astrocyte-secreted CCL2. J Immunol, 2012. 188(8): p. 3876-85.
  3. Cary, D.C., J.E. Clements, and A.J. Henderson, RON Receptor Tyrosine Kinase, a Negative Regulator of Inflammation, Is Decreased during Simian Immunodeficiency Virus-Associated Central Nervous System Disease. J Immunol, 2013. 191(8): p. 4280-4287.
  4. Liu, J., et al., Tristetraprolin expression and microRNA-mediated regulation during simian immunodeficiency virus infection of the central nervous system. Mol Brain, 2013. 6: p. 40.
  5. Russell, J.N., J.E. Clements, and L. Gama, Quantitation of gene expression in formaldehyde-fixed and fluorescence-activated sorted cells. PLoS One, 2013. 8(9): p. e73849.
  6. Sisk, J.M., et al., SIV replication is directly downregulated by four antiviral miRNAs. Retrovirology, 2013. 10(1): p. 95.
  7. Zaritsky, L.A., et al., Tissue-Specific Interferon Alpha Subtype Response to SIV Infection in Brain, Spleen, and Lung. J Interferon Cytokine Res, 2013. 33(1): p. 24-33.
  8. Abreu, C.M., et al., Dual role of novel ingenol derivatives from Euphorbia tirucalli in HIV replication: inhibition of de novo infection and activation of viral LTR. PLoS One, 2014. 9(5): p. e97257.
  9. Akay, C., et al., Antiretroviral drugs induce oxidative stress and neuronal damage in the central nervous system. J Neurovirol, 2014. 20(1): p. 39-53.
  10. Witwer, K.W., et al., TRIM19-positive and TRIM19-negative cells in and around a perivascular cuff of CD68-positive macrophages. AIDS Res Hum Retroviruses, 2014. 30(4): p. 333-4.

Dr. Chris Zink

  1. Gama, L., et al., Expansion of a subset of CD14highCD16negCCR2low/neg monocytes functionally similar to myeloid-derived suppressor cells during SIV and HIV infection. J Leukoc Biol, 2012. 91(5): p. 803-16.
  2. Meulendyke, K.A., et al., Early Minocycline Treatment Prevents a Decrease in Striatal Dopamine in an SIV Model of HIV-Associated Neurological Disease. J Neuroimmune Pharmacol, 2012. 7(2): p. 454-64.
  3. Ravimohan, S., et al., Early emergence and selection of a SIV-LTR C/EBP site variant in SIV-infected macaques that increases virus infectivity. PLoS One, 2012. 7(8): p. e42801.
  4. Baxter, V.K., et al., Serum albumin and body weight as biomarkers for the antemortem identification of bone and gastrointestinal disease in the common marmoset. PLoS One, 2013. 8(12): p. e82747.
  5. Nzowa, L.K., et al., Two new tryptophan derivatives from the seed kernels of Entada rheedei: effects on cell viability and HIV infectivity. Fitoterapia, 2013. 87: p. 37-42.
  6. Akay, C., et al., Antiretroviral drugs induce oxidative stress and neuronal damage in the central nervous system. J Neurovirol, 2014. 20(1): p. 39-53.
  7. Drewes, J.L., et al., Attenuation of pathogenic immune responses during infection with human and simian immunodeficiency virus (HIV/SIV) by the tetracycline derivative minocycline. PLoS One, 2014. 9(4): p. e94375.
  8. Meulendyke, K.A., et al., Elevated Brain Monoamine Oxidase Activity in SIV- and HIV-associated Neurological Disease. J Infect Dis, 2014.
  9. Witwer, K.W., et al., TRIM19-positive and TRIM19-negative cells in and around a perivascular cuff of CD68-positive macrophages. AIDS Res Hum Retroviruses, 2014. 30(4): p. 333-4.
  10. Zink, M.C., et al., Evaluation of the risk and age of onset of cancer and behavioral disorders in gonadectomized Vizslas. J Am Vet Med Assoc, 2014. 244(3): p. 309-19.

Dr. Joe Mankowski

  1. Helke, K.L., S.E. Queen, and J.L. Mankowski, 14-3-3 Protein in CSF Reflects SIV-Mediated Pre-Synaptic Damage. Curr HIV Res, 2013. 11(4): p. 281-7.
  2. Kelly, K.M., et al., Neuroprotective maraviroc monotherapy in SIV-infected macaques: reduced replicating and latent SIV in the brain. AIDS, 2013.
  3. Metcalf Pate, K.A., et al., Platelet Activation and Platelet-Monocyte Aggregate Formation Contribute to Decreased Platelet Count During Acute Simian Immunodeficiency Virus Infection in Pig-tailed Macaques. J Infect Dis, 2013.
  4. Sasseville, V.G., et al., Meeting Report: Emerging Respiratory Viral Infections and Nonhuman Primate Case Reports. Vet Pathol, 2013.
  5. Akay, C., et al., Antiretroviral drugs induce oxidative stress and neuronal damage in the central nervous system. J Neurovirol, 2014. 20(1): p. 39-53.
  6. Dorsey, J.L., et al., Loss of Corneal Sensory Nerve Fibers in SIV-Infected Macaques: An Alternate Approach to Investigate HIV-Induced PNS Damage. Am J Pathol, 2014. 184(6): p. 1652-9.
  7. Kelly, K.M., et al., CCR5 inhibition prevents cardiac dysfunction in the SIV/macaque model of HIV. J Am Heart Assoc, 2014. 3(2): p. e000874.
  8. Mangus, L.M., et al., Unraveling the Pathogenesis of HIV Peripheral Neuropathy: Insights from a Simian Immunodeficiency Virus Macaque Model. ILAR J, 2014. 54(3): p. 296-303.
  9. Metcalf Pate, K.A., et al., TGFbeta-Mediated Downregulation of Thrombopoietin Is Associated With Platelet Decline in Asymptomatic SIV Infection. J Acquir Immune Defic Syndr, 2014. 65(5): p. 510-6.
  10. Witwer, K.W., et al., TRIM19-positive and TRIM19-negative cells in and around a perivascular cuff of CD68-positive macrophages. AIDS Res Hum Retroviruses, 2014. 30(4): p. 333-4.
Dr. David Graham
  1. Brown, J.M., N.J. Shaw, and D.R. Graham, The first five years: a mixed methods study investigating reflections on working as a hospital consultant. JRSM Short Rep, 2013. 4(5): p. 2042533313476686.
  2. Linde, M.E., et al., The conserved set of host proteins incorporated into HIV-1 virions suggests a common egress pathway in multiple cell types. J Proteome Res, 2013. 12(5): p. 2045-54.
  3. Nzowa, L.K., et al., Two new tryptophan derivatives from the seed kernels of Entada rheedei: effects on cell viability and HIV infectivity. Fitoterapia, 2013. 87: p. 37-42.
  4. Tavano, B., et al., Ig-like transcript 7, but not bone marrow stromal cell antigen 2 (also known as HM1.24, tetherin, or CD317), modulates plasmacytoid dendritic cell function in primary human blood leukocytes. J Immunol, 2013. 190(6): p. 2622-30.
  5. Tovar, Y.R.L.B., et al., Adenosine Triphosphate Released from HIV-Infected Macrophages Regulates Glutamatergic Tone and Dendritic Spine Density on Neurons. J Neuroimmune Pharmacol, 2013.
  6. Ubaida Mohien, C., et al., A Bioinformatics Approach for Integrated Transcriptomic and Proteomic Comparative Analyses of Model and Non-sequenced Anopheline Vectors of Human Malaria Parasites. Mol Cell Proteomics, 2013. 12(1): p. 120-31.
  7. Drewes, J.L., et al., Attenuation of pathogenic immune responses during infection with human and simian immunodeficiency virus (HIV/SIV) by the tetracycline derivative minocycline. PLoS One, 2014. 9(4): p. e94375.
  8. Kelly, K.M., et al., CCR5 inhibition prevents cardiac dysfunction in the SIV/macaque model of HIV. J Am Heart Assoc, 2014. 3(2): p. e000874.
  9. Meulendyke, K.A., et al., Elevated Brain Monoamine Oxidase Activity in SIV- and HIV-associated Neurological Disease. J Infect Dis, 2014.
  10. Royle, C.M., et al., Modulation of HIV-1-induced activation of plasmacytoid dendritic cells by 6-desfluoroquinolones. AIDS Res Hum Retroviruses, 2014. 30(4): p. 345-54.
Dr. Lucio Gama
  1. Gama, L., et al., Expansion of a subset of CD14highCD16negCCR2low/neg monocytes functionally similar to myeloid-derived suppressor cells during SIV and HIV infection. J Leukoc Biol, 2012. 91(5): p. 803-16.
  2. Ravimohan, S., et al., Early emergence and selection of a SIV-LTR C/EBP site variant in SIV-infected macaques that increases virus infectivity. PLoS One, 2012. 7(8): p. e42801.
  3. Zaritsky, L.A., L. Gama, and J.E. Clements, Canonical type I IFN signaling in simian immunodeficiency virus-infected macrophages is disrupted by astrocyte-secreted CCL2. J Immunol, 2012. 188(8): p. 3876-85.
  4. Liu, J., et al., Tristetraprolin expression and microRNA-mediated regulation during simian immunodeficiency virus infection of the central nervous system. Mol Brain, 2013. 6: p. 40.
  5. Metcalf Pate, K.A., et al., Platelet Activation and Platelet-Monocyte Aggregate Formation Contribute to Decreased Platelet Count During Acute Simian Immunodeficiency Virus Infection in Pig-tailed Macaques. J Infect Dis, 2013.
  6. Russell, J.N., J.E. Clements, and L. Gama, Quantitation of gene expression in formaldehyde-fixed and fluorescence-activated sorted cells. PLoS One, 2013. 8(9): p. e73849.
  7. Zaritsky, L.A., et al., Tissue-Specific Interferon Alpha Subtype Response to SIV Infection in Brain, Spleen, and Lung. J Interferon Cytokine Res, 2013. 33(1): p. 24-33.
  8. Abreu, C.M., et al., Dual role of novel ingenol derivatives from Euphorbia tirucalli in HIV replication: inhibition of de novo infection and activation of viral LTR. PLoS One, 2014. 9(5): p. e97257.
  9. Meulendyke, K.A., et al., Elevated Brain Monoamine Oxidase Activity in SIV- and HIV-associated Neurological Disease. J Infect Dis, 2014.
  10. Witwer, K.W., et al., TRIM19-positive and TRIM19-negative cells in and around a perivascular cuff of CD68-positive macrophages. AIDS Res Hum Retroviruses, 2014. 30(4): p. 333-4.
Dr. Kenneth Witwer
  1. Sisk, J.M., et al., SIV replication is directly downregulated by four antiviral miRNAs. Retrovirology, 2013. 10(1): p. 95.
  2. Witwer, K.W., Data Submission and Quality in Microarray-Based MicroRNA Profiling. Clin Chem, 2013. 59(2): p. 392-400.
  3. Witwer, K.W., et al., Standardization of sample collection, isolation and analysis methods in extracellular vesicle research. J Extracell Vesicles, 2013. 2.
  4. Witwer, K.W., et al., Real-time quantitative PCR and droplet digital PCR for plant miRNAs in mammalian blood provide little evidence for general uptake of dietary miRNAs: Limited evidence for general uptake of dietary plant xenomiRs. RNA Biol, 2013. 10(7).
  5. Yu, I.W., et al., OpenArray profiling reveals no differential modulation of miRNA by positive and negative CD4+ T-cell immunoselection. Exp Hematol, 2013.
  6. Christofidou-Solomidou, M., et al., Dietary flaxseed modulates the miRNA profile in irradiated and non-irradiated murine lungs: A novel mechanism of tissue radioprotection by flaxseed. Cancer Biol Ther, 2014. 15(7).
  7. Meulendyke, K.A., et al., Elevated Brain Monoamine Oxidase Activity in SIV- and HIV-associated Neurological Disease. J Infect Dis, 2014.
  8. Witwer, K.W., HIV-1 Tat- and Vpr-responsive microRNAs of neuronal cells. J Biol Chem, 2014. 289(5): p. 3104.
  9. Witwer, K.W., et al., TRIM19-positive and TRIM19-negative cells in and around a perivascular cuff of CD68-positive macrophages. AIDS Res Hum Retroviruses, 2014. 30(4): p. 333-4.
  10. Witwer, K.W. and K.D. Hirschi, Transfer and functional consequences of dietary microRNAs in vertebrates: concepts in search of corroboration: negative results challenge the hypothesis that dietary xenomiRs cross the gut and regulate genes in ingesting vertebrates, but important questions persist. Bioessays, 2014. 36(4): p. 394-406.
Dr. Kelly Metcalf Pate
  1. Metcalf Pate, K.A., et al., Effect of sampling strategy on the detection of fur mites within a naturally infested colony of mice (Mus musculus). J Am Assoc Lab Anim Sci, 2011. 50(3): p. 337-43.
  2. Pate, K.A.M., et al., Effect of Sampling Strategy on the Detection of Fur Mites within a Naturally Infested Colony of Mice (Mus musculus). Journal of the American Association for Laboratory Animal Science, 2011. 50(3): p. 337-343.
  3. Baxter, V.K., et al., Serum albumin and body weight as biomarkers for the antemortem identification of bone and gastrointestinal disease in the common marmoset. PLoS One, 2013. 8(12): p. e82747.
  4. Kelly, K.M., et al., Neuroprotective maraviroc monotherapy in SIV-infected macaques: reduced replicating and latent SIV in the brain. AIDS, 2013.
  5. Metcalf Pate, K.A., et al., Platelet Activation and Platelet-Monocyte Aggregate Formation Contribute to Decreased Platelet Count During Acute Simian Immunodeficiency Virus Infection in Pig-tailed Macaques. J Infect Dis, 2013.
  6. Rice, K.A., et al., Evaluation of diagnostic methods for Myocoptes musculinus according to age and treatment status of mice (Mus musculus). J Am Assoc Lab Anim Sci, 2013. 52(6): p. 773-81.
  7. Rice, K.A., et al., Diagnosis of amyloidosis and differentiation from chronic, idiopathic enterocolitis in rhesus (Macaca mulatta) and pig-tailed (M. nemestrina) macaques. Comp Med, 2013. 63(3): p. 262-71.
  8. Dorsey, J.L., et al., Loss of Corneal Sensory Nerve Fibers in SIV-Infected Macaques: An Alternate Approach to Investigate HIV-Induced PNS Damage. Am J Pathol, 2014. 184(6): p. 1652-9.
  9. Kelly, K.M., et al., CCR5 inhibition prevents cardiac dysfunction in the SIV/macaque model of HIV. J Am Heart Assoc, 2014. 3(2): p. e000874.
  10. Metcalf Pate, K.A., et al., TGFbeta-Mediated Downregulation of Thrombopoietin Is Associated With Platelet Decline in Asymptomatic SIV Infection. J Acquir Immune Defic Syndr, 2014. 65(5): p. 510-6.
 
 
 
 
 
 
 

© The Johns Hopkins University, The Johns Hopkins Hospital, and Johns Hopkins Health System. All rights reserved.

Privacy Policy and Disclaimer