MONDAY
July 30, 2012 | INTRODUCTION to Mouse Pathobiology & Phenotyping
+ EXHIBITS + POSTERSWeb Resources; Summary Tables, references (23 p PDF) |
9-10am | Brayton - Introduction to phenotyping, mouse genetics, nomenclature & Famous Mice (16p PDF) |
10-11 | Brayton - Common Spontaneous Phenotypes and Diseases (non infectious) (10p PDF) |
11-12 | Watson - Environmental influences on phenotypes 1
What is in your mouse environment? (lectures 1,2 - 18p PDF) |
12-1 | LUNCH - VISIT EXHIBITS + POSTERS + Medical Illustration Art Exhibit |
1-2 | Watson - Environmental influences on phenotypes 2
What ELSE can impact your research and phenotypes: Your Surveillance Program ... |
2-3 | Brayton - Infections & infectious phenotypes that can impact your research (19p PDF) |
3-4 | Brayton - Immunodeficient Mice - options & challenges (11p PDF) |
4-5 | Karim - Pathology and Phenotyping GEM intestinal Cancers (7p PDF) |
5-7pm | |
TUESDAY | GEM & Multidisciplinary Phenotyping
+ EXHIBITS |
9-10 | Hawkins/Reeves – Making Mice - traditional and new transgenic technologies (6p PDF) |
10-11 | Doyle / Shaw - Ophthalmic Phenotyping (6p PDF) |
11-12 | Lauer/May - Auditory/acoustic Phenotyping (5p PDF) |
12-1 | LUNCH & Tours - CMOR (metabolic) & BRB Imaging, Behavioral + EXHIBITS + POSTERS |
1-2 | Potter/Pletnikov – Emotional / Cognitive Phenotyping (6p PDF) |
2-3 | Aja - Metabolic Phenotypes & Phenotyping (6p PDF) |
3-4 | Mitzner – Pulmonary/Respiratory Phenotypes & Phenotyping (12p PDF) |
4-530 | Pomper - IMAGING for Phenotyping (10p PDF) Gabrielson - Cardiovascular phenotyping: In vivo functional correlations to pathology (6p PDF) |
WEDNESDAY
| Practical Phenotyping 1
DOWNLOAD LAB MANUAL - 41p PDF |
9-10 | Watson - Clinical / Physical Exam - Modified SHIRPA (refer to Lab Manual) |
10-11 | Brayton - Clinical Pathology - oversimplified (13p PDF) |
11-12 | Brayton & al - Online & other Resources (refer to web resources - above)) |
12-1 | LUNCH (on your own) & Tours - CMOR (metabolic) & BRB Imaging, Behavioral |
130-3pm | Watson / Forbes & al
LAB 1: Clinical Examination (refer to Lab Manual) |
315-5pm | Forbes / Brayton & al
LAB 2: Clinical Pathology and Specimen collection (refer to Lab Manual) |
THURSDAY
| Practical Phenotyping 2 |
9-10 | Brayton - Anatomic Pathology Phenotyping - Necropsy (refer to Lab Manual) |
10-11 | Brayton - Anatomic Pathology Phenotyping - Trimming (refer to Lab Manual) |
11-12 | Brayton - Microscopic Anatomy & Pathology by
Virtual Microscopy (refer to Lab Manual) |
12-1 | LUNCH (on your own) |
1-4 | Forbes / Brayton et al. LAB 3: Anatomic Pathology - Necropsy (refer to Lab Manual) |
4-6pm | Digital/Virtual Slide Conference - with refreshments |
FRIDAY
| Practical Phenotyping 3
Advanced Pathology for Phenotyping & Translational Research |
9-11 | Forbes / Brayton et al.
LAB 4: Anatomic Pathology - Trimming (refer to Lab Manual) |
11-12 | A Meeker - Basic Immunohistochemistry - principles and protocol development (9p PDF) |
12-1 | LUNCH |
1-2 | J Ward - Evaluation of Embryos & Pups (14p PDF) |
2-3 | D Haines & M Anver - Pathology Core Support for Basic and Translational Research: GEM, Xeno, and Nano (9p PDF) |
| 3-4 | T Cornish – digital microscopy, quantitative microscopy for research applications and publication (10p PDF) |
5pm | Quizzes Due ! for course ME680.712
TURN in to BRB 851 |
MOUSE PATHOBIOLOGY & PHENOTYPING MANUAL1st ed. 2009 selected sections available to download here.
Register for this course, or contact Dr. Brayton for updated revisions. Section 1
Spontaneous Phenotypes and Conditions in Common Mouse Strains & Stocks Section 2
Infectious Agents and Phenotypes in Mice Section 3
Mouse Pathology Glossary: Non Neoplastic; Neoplastic Section 4
Anatomic Pathology - Necropsy & Trimming Protocol Section 5
(Relatively) Non Invasive Phenotyping Section 6
Clinical Pathology Resources Section 7
Metabolic Phenotyping Resources Section 8
Pregnancy, embryo, pup evaluation |
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MORE 2012 course/lecture materialBrayton 1-2: Intro Phenotyping and Famous Mice (PDF) Brayton 3: Infectious Disease Phenotypes (PDF) Brayton 4: 'Spontaneous Disease' Phenotypes (PDF) Cardiff: Modelling Cancer in GEM (PDF) FYI Check out Veterinary Pathology's January 2012 Special Focus Issue on Genetically Engineered Mice http://vet.sagepub.com/content/current |
Brayton: In vivo Imaging and Pathology for Phenotyping (PDF) Garrett: Anesthesia and Clinical Considerations for Small Animal Imaging (PDF) |
Brayton 2012 Mouse Cancer Models Lecture |
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For additional Course information or to to order a complete manual, or
to provide feedback or suggestions - contact Dr. Brayton. |
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