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2012 Mouse Pathobiology and Phenotyping Short Course

July 30 - August 3, 2012  

Short Course & Workshop on Mouse Biology, Pathology, Genetics for Phenotyping and Translational Research
[concurrent with graduate school course ME 680.712]

At Johns Hopkins University School of Medicine, 
Baltimore, MD USA

TARGET AUDIENCE: Scientists, faculty, postdocs, graduate students, veterinarians, pathologists who use or expect to use mice in translational research.

AIMS: To provide information, practical tools and skills essential to the optimal use of mice in translational research. 

FORMAT & TOPICS: 5 day short-course on mouse biology, pathology, genetics, practical and multidisciplinary phenotyping for translational research, including lectures, 3 hands on laboratory session, exhibits, tours, poster session, pathology slide conference.
DVM/VMD RACE 36.5 credit hrs.

SYLLABUS:  MOUSE PATHOBIOLOGY & PHENOTYPING MANUAL is the core syllabus material, several sections can be downloaded (free)    
Additional syllabus/lecture material will be uploaded before the course, and provided at the course.


JHU REGISTRATION - CLOSED
(Grad Students, Postdocs, Faculty and Staff) 

After July 1, call or email for availability of laboratory sessions.
For graduate students and postdocs, this is graduate school course ME:680.712


 NON-JHU REGISTRATION - CLOSED
Early registration (before July 1):
$800 for Lectures + Hands on Laboratory Sessions, $600 for Lectures Only.
After July 1: $1,000 for Lectures and Lab Sessions (call or email for availability), 
$800 for Lectures Only.

 Pheno symposium logo

Visit Exhibits
9am Monday to
5pm Tuesday.

2012 EXHIBITORS

HARLAN LABORATORIES INC

Tucker-Davis Technologies

CRC PRESS

ELSEVIER

WILEY BLACKWELL


JHU CORES

PHENOTYPING CORE

BRB BEHAVIOR COREMultiplex ELISA Core

CMOR CENTER FOR METABOLISM AND OBESITY RESEARCH



CMOR CENTER FOR METABOLISM AND OBESITY RESEARCH

   

     2012 Program


MONDAY
July 30, 2012

INTRODUCTION to Mouse Pathobiology & Phenotyping
+ EXHIBITS + POSTERS

Web Resources; Summary Tables, references  (23 p PDF)

9-10am
Brayton - Introduction to phenotyping, mouse genetics, nomenclature & Famous Mice (16p PDF)
10-11
Brayton - Common Spontaneous Phenotypes and Diseases (non infectious) (10p PDF)
11-12
Watson - Environmental influences on phenotypes 1
What is in your mouse environment? (lectures 1,2 - 18p PDF)
12-1
LUNCH - VISIT EXHIBITS + POSTERS
+ Medical Illustration Art Exhibit
1-2
Watson - Environmental influences on phenotypes 2 
What ELSE can impact your research and phenotypes: Your Surveillance Program ...
2-3
Brayton - Infections & infectious phenotypes that can impact your research (19p PDF)
3-4
Brayton - Immunodeficient Mice - options & challenges (11p PDF)
4-5
Karim - Pathology and Phenotyping GEM intestinal Cancers (7p PDF)
5-7pm
RECEPTION, EXHIBITS & 
POSTER SESSION (Poster Abstracts - PDF)

TUESDAY

GEM & Multidisciplinary Phenotyping
+ EXHIBITS

9-10
Hawkins/Reeves – Making Mice - traditional and new transgenic technologies (6p PDF)
10-11
Doyle / Shaw - Ophthalmic Phenotyping (6p PDF)
11-12
Lauer/May - Auditory/acoustic Phenotyping (5p PDF)
 12-1
LUNCH & Tours - CMOR (metabolic) & BRB Imaging, Behavioral + EXHIBITS + POSTERS
1-2
Potter/Pletnikov – Emotional / Cognitive Phenotyping (6p PDF)
2-3
Aja - Metabolic Phenotypes & Phenotyping (6p PDF)
3-4
Mitzner – Pulmonary/Respiratory Phenotypes & Phenotyping (12p PDF)   
4-530
Pomper - IMAGING for Phenotyping (10p PDF)
Gabrielson - Cardiovascular phenotyping: In vivo functional correlations to pathology (6p PDF)

WEDNESDAY

Practical Phenotyping 1
DOWNLOAD LAB MANUAL - 41p PDF

9-10
Watson - Clinical / Physical Exam - Modified SHIRPA (refer to Lab Manual)
10-11
Brayton - Clinical Pathology - oversimplified (13p PDF)
11-12
Brayton & al - Online & other Resources (refer to web resources - above))
 12-1
LUNCH (on your own) & Tours - CMOR (metabolic) & BRB Imaging, Behavioral
 130-3pm
Watson / Forbes  & al
LAB 1: Clinical Examination (refer to Lab Manual)
 315-5pm
Forbes / Brayton  & al
LAB 2: Clinical Pathology and Specimen collection (refer to Lab Manual)

THURSDAY

Practical Phenotyping 2

9-10
Brayton - Anatomic Pathology Phenotyping - Necropsy (refer to Lab Manual)
10-11
Brayton - Anatomic Pathology Phenotyping - Trimming (refer to Lab Manual)
11-12
Brayton - Microscopic Anatomy & Pathology by
Virtual Microscopy (refer to Lab Manual)
12-1
LUNCH (on your own)
1-4    
Forbes / Brayton et al.
LAB 3: Anatomic Pathology - Necropsy (refer to Lab Manual)
4-6pm
Digital/Virtual Slide Conference - with refreshments

FRIDAY

Practical Phenotyping 3
Advanced Pathology for Phenotyping & Translational Research

9-11
Forbes / Brayton et al. 
LAB 4: Anatomic Pathology - Trimming (refer to Lab Manual)
11-12
A Meeker - Basic Immunohistochemistry - principles and protocol development (9p PDF)
12-1
LUNCH
1-2
J Ward - Evaluation of Embryos & Pups (14p PDF)
2-3
D Haines & M Anver - Pathology Core Support for Basic and Translational Research: GEM, Xeno, and Nano (9p PDF)
3-4T Cornish – digital microscopy, quantitative microscopy for research applications and publication (10p PDF)
5pm
Quizzes Due ! for course ME680.712
TURN in to BRB 851

         

MOUSE PATHOBIOLOGY & PHENOTYPING MANUAL


1st ed. 2009 selected sections available to download here.
Register for this course, or
contact Dr. Brayton for updated revisions.
Section 1
Spontaneous Phenotypes and Conditions in
Common Mouse Strains & Stocks
 Section 2 
Infectious Agents and Phenotypes in Mice
Section 3
Mouse Pathology Glossary: Non Neoplastic; Neoplastic
Section 4 
Anatomic Pathology - Necropsy & Trimming Protocol
Section 5 
(Relatively) Non Invasive Phenotyping
Section 6
Clinical Pathology Resources
Section 7
Metabolic Phenotyping Resources
Section 8
Pregnancy, embryo, pup evaluation
 

     

 

       For additional Course information or to to order a complete manual, or
to provide feedback or suggestions - contact  Dr. Brayton.

SAIRP Small Animal Imaging Resource Program

TMA & Immunohistochemistry Core

 Transgenic & ES Cell  Core

  
 
 
 
 
 

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