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2011 Mouse Pathobiology and Phenotyping Short Course

July 25-29, 2011

Short Course & Workshop on Mouse Biology, Pathology, Genetics for Phenotyping and Translational Research
[concurrent with graduate school course ME 680.712]

At Johns Hopkins University School of Medicine, 
Baltimore, MD USA

TARGET AUDIENCE: Scientists, faculty, postdocs, graduate students, veterinarians, pathologists who use or expect to use mice in translational research.

AIMS: To provide information, practical tools and skills essential to the optimal use of mice in translational research. 

FORMAT: 5 day short-course on mouse biology, pathology, genetics, practical and multidisciplinary phenotyping for translational research, including lectures, 3 hands on laboratory session, exhibits, tours, poster session, pathology slide conference.
DVM/VMD RACE APPROVED 36.5 hrs.

SYLLABUS:  MOUSE PATHOBIOLOGY & PHENOTYPING MANUAL is the core syllabus material, several sections can be downloaded (free)    
Additional syllabus/lecture material is provided at the course.

   Visit Exhibits
9am Monday to
5pm Tuesday.

APERIO

THE JACKSON LABORATORY

CRC PRESS

 Exhibitors contact welza1@jhmi.edu for more information

   

BWI is the closest airport
BAL is the closest Amtrak station

More about JHUSOM course ME680.712
Tuition Remission Course 80026792

Contact us for more information:
cbrayton@jhmi.edu

 

    
2011 Program

 

MONDAY
July 25, 2011 

INTRODUCTION to Mouse Pathobiology & Phenotyping
+ EXHIBITS

9-10am
Brayton - Introduction to phenotyping, fundamental mouse genetics and biology, mouse and gene nomenclature
10-11
Brayton - Famous Mice & Phenotypes
11-12
Watson - Environmental influences on phenotypes 1
What is in your mouse environment?
12-1
LUNCH - VISIT EXHIBITS + POSTERS
1-2
Watson - Environmental influences on phenotypes 2 
What ELSE can impact your research and phenotypes: Your Surveillance Program ...
2-3
Brayton - Infections & infectious phenotypes that can impact your research
3-4
Brayton - Immunodeficient Mice - options & challenges
4-5
Karim - Pathology and Phenotyping GEM intestinal Cancers
5-7pm
RECEPTION, EXHIBITS & POSTER SESSION

TUESDAY
July 26, 2011

GEM & Multidisciplinary Phenotyping
+ EXHIBITS

9-10
Lawler/Reeves – Making Mice - traditional and new transgenic technologies
10-11
Sinha - Ophthalmic Phenotyping
11-12
Lauer/May - Auditory/acoustic phenotyping
 12-1
LUNCH & Tours - CMOR (metabolic) & BRB Imaging, Behavioral
+ visit EXHIBITS + POSTERS
1-2
Pletnikov/Yocum – Emotional / cognitive phenotyping
2-3
Aja/Ronnet - Metabolic Phenotypes & Phenotyping
3-4
Tankersly/Mitzner – Pulmonary/Respiratory Phenotypes & Phenotyping   
4-530
Pomper - IMAGING for Phenotyping
Gabrielson - Cardiovascular phenotyping: In vivo functional correlations to pathology

WEDNESDAY
July 27, 2011

Practical Phenotyping 1

9-10
Watson - Clinical / Physical Exam - Modified SHIRPA
10-11
Brayton - Clinical Pathology - oversimplified
11-12
Brayton & al - Online & other Resources
 12-1
LUNCH & Tours - CMOR (metabolic) & BRB Imaging, Behavioral
 130-3pm
Watson / Forbes  & al
LAB 1: Clinical Examination
 315-5pm
Forbes / Brayton  & al
LAB 2: Clinical Pathology and Specimen collection 

THURSDAY
July 28, 2011

Practical Phenotyping 2

9-10
Brayton - Anatomic Pathology Phenotyping - Necropsy
10-11
Brayton - Anatomic Pathology Phenotyping - Trimming
11-12
Brayton - Microscopic Anatomy & Pathology by
Virtual Microscopy
12-1
LUNCH
1-4    
Forbes / Brayton / Wilcox  al. 
LAB 3: Anatomic Pathology - Necropsy
4-6pm
Slide Conference - with refreshments

FRIDAY
July 29, 2011

Practical Phenotyping 3
Advanced Pathology for Phenotyping & Translational Research

9-11
Forbes / Brayton / Wilcox  al. 
LAB 4: Anatomic Pathology - Trimming
11-12
A Meeker - Basic Immunohistochemistry - principles and protocol development
12-1
LUNCH
1-2
J Ward - Evaluation of Embryos & Pups
2-3
D Haines & M Anver - Pathology Core Support for Basic and Translational Research: GEM, Xeno, and Nano
3-4T Cornish – digital microscopy, quantitative microscopy for research applications and publication
5pm
Quizzes Due ! for course ME680.712
TURN in to BRB 851

POSTER SESSION

Monday-Tuesday, July 25-26,  Abstract deadline: July 1, 2011
Scientific and Technical posters relevant to phenotyping (any species) & translational research (mice) are invited.  Email abstract (250 word limit) to Dr. Brayton (click here). 
The poster session will be in the exhibit area,
9am Monday through 5pm Tuesday. 
Authors should attend posters Monday 5-6pm during the reception. 

SLIDE CONFERENCE

Thursday, July 28, 4-6pm
Case / Slide Submission deadline: July 1, 2011

Glass Slides, Virtual slides, cases relevant to phenotyping & translational research (any species, but especially mice) are invited. Each submitter will have approximately 10 minutes to present & discuss a case.   Limited to 20 cases - submit early to be included.   Email case information and queries to Dr. Brayton (click here).

         

MOUSE PATHOBIOLOGY & PHENOTYPING MANUAL


1st ed. 2009 selected sections available to download here.
Register for this course, or
contact Dr. Brayton for updated revisions.
Section 1
Spontaneous Phenotypes and Conditions in
Common Mouse Strains & Stocks
 Section 2 
Infectious Agents and Phenotypes in Mice
Section 3
Mouse Pathology Glossary: Non Neoplastic; Neoplastic
Section 4 
Anatomic Pathology - Necropsy & Trimming Protocol
Section 5 
(Relatively) Non Invasive Phenotyping
Section 6
Clinical Pathology Resources
Section 7
Metabolic Phenotyping Resources
Section 8
Pregnancy, embryo, pup evaluation
 

        

Previous Courses & Symposia

Visit 2007 JHU Symposium Site
 
 
      For additional Course information or to to order a complete manual, or
to provide feedback or suggestions - contact  Dr. Brayton.
 
 
 
 
 

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