Skip Navigation
 
 
 
 
Print This Page
Share this page: More

2010 Mouse Pathobiology and Phenotyping Course

Mouse Pathobiology and Phenotyping Short Course & Workshop on Mouse Biology, Pathology, Genetics for Phenotyping and Translational Research
[Concurrent with graduate School Course ME 680.712]

Short Course & Workshop at Johns Hopkins, Baltimore, MD USA

July 12-16, 2010

TARGET AUDIENCE: Scientists, faculty, postdocs, graduate students, veterinarians, pathologists who use or expect to use mice in translational research.

AIMS: To provide information, practical tools and skills essential to the optimal use of mice in translational research. 

FORMAT: 5day short-course on mouse biology, pathology, genetics, practical and multidisciplinary phenotyping for translational research, including lectures, 3 hands on laboratory session, exhibits, tours, poster session, pathology slide conference 

SYLLABUS:  The MOUSE PATHOBIOLOGY & PHENOTYPING MANUAL is the core syllabus material, several sections can be downloaded (free) by section from this site.  Softbound complete copies can be purchased ($50).  It is updated at least annually.  Additional course materials to be provided at the course

 

DVM/VMD RACE approved for 36.5 Hr

 

***** 

PROGRAM

 
MONDAY 
July 12, 2010 
INTRODUCTION to Mouse Pathobiology & Phenotyping
+ EXHIBITS
9-10am
Brayton - Introduction to phenotyping, fundamental mouse genetics and biology, mouse and gene nomenclature
10-11
Brayton - Famous Mice & Phenotypes
11-12
Watson - Environmental influences on phenotypes 1
What is in your mouse environment?
12-1
LUNCH - VISIT EXHIBITS
1-2
Watson - Environmental influences on phenotypes 2 
What ELSE can impact your research and phenotypes: Your Surveillance Program ...
2-3
Brayton - Infections & infectious phenotypes that can impact your research
3-4
Brayton - Immunodeficient Mice - options & challenges
4-5
Huso - Good News from the pathologists! Phenotype confirmation & characterization with pathology
5-7pm
RECEPTION, EXHIBITS & POSTER SESSION
    
TUESDAY
July 13, 2010
GEM & Multidisciplinary Phenotyping
+ EXHIBITS
9-10
Reeves – Making Mice - traditional and new transgenic technologies
10-11
Sinha - Ophthalmic Phenotyping
11-12
May - Auditory/acoustic phenotyping
 12-1
LUNCH & Tours - CMOR (metabolic) & BRB Imaging, Behavioral
+ visit EXHIBITS
1-2
Pletnikov – Emotional / cognitive phenotyping
2-3
Aja/Ronnet - Metabolic Phenotypes & Phenotyping
3-4
Mitzner – Pulmonary/Respiratory Phenotypes & Phenotyping   
4-530
Pomper/Gabrielson - IMAGING for Phenotyping
Gabrielson - Cardiovascular phenotyping: In vivo functional correlations to pathology
   
WEDNESDAY
July 14, 2010
Practical Phenotyping 1
9-10
Watson - Clinical / Physical Exam - Modified SHIRPA
10-11
Brayton - Clinical Pathology - oversimplified
11-12
Brayton & al - Online & other Resources
 12-1
LUNCH & Tours - CMOR (metabolic) & BRB Imaging, Behavioral
 130-3pm
Watson / Forbes  & al
LAB 1: Clinical Examination
 315-5pm
 Forbes / Brayton  & al
LAB 2: Clinical Pathology and Specimen collection 
     
THURSDAY
July 15, 2010
Practical Phenotyping 2
9-10
Brayton - Anatomic Pathology Phenotyping - Necropsy
10-11
Brayton - Anatomic Pathology Phenotyping - Trimming
11-12
Brayton - Microscopic Anatomy & Pathology by
Virtual Microscopy
12-1
LUNCH
1-4    
Forbes / Brayton / Wilcox  al. 
LAB 3: Anatomic Pathology - Necropsy
4-6pm
Slide Conference - with refreshments
 
FRIDAY
July 16, 2010
Practical Phenotyping 3
FINAL QUIZ for  ME 680.712
Advanced Pathology for Phenotyping & Translational Research
9-11
Forbes / Brayton / Wilcox  al. 
LAB 4: Anatomic Pathology - Trimming
11-12
QUIZ (Final exam for ME680.712)
12-1
LUNCH
1-2
J Ward - Evaluation of Embryos & Pups
2-3
M Anver - Immunohistochemistry in Phenotyping
3-4
DC Haines - Lesions & IHC of Aged Mice & GEM
4-5pm
K McDorman - Quantitative Pathology - Analysis & Data Management
  
 

*****

Monday-Tuesday, July 12-13, Concurrent POSTER SESSION
Abstract deadline: June 14, 2010.  
The poster session will be in the exhibit area,
9am Monday through 5pm Tuesday. 
Authors should attend posters Monday 5-6pm during the reception. 

*****

Thursday, July 15, SLIDE CONFERENCE 4-6pm
Submission deadline: June 14, 2010.  
Glass Slides, Virtual slides, cases relevant to phenotyping & translational research (any species, but especially mice)*****

 

MOUSE PATHOBIOLOGY & PHENOTYPING MANUAL


1st ed. 2009 selected sections available to download
Section 1
Spontaneous Phenotypes and Conditions in
Common Mouse Strains & Stocks
Section 2
Infectious Agents and Phenotypes in Mice
Section 3
Mouse Pathology Glossary: Non Neoplastic; Neoplastic
Section 4
Anatomic Pathology - Necropsy & Trimming Protocol
Section 4a
Anatomic Pathology - powerpoint presentation
Section 5
(Relatively) Non Invasive Phenotyping
Section 6
Clinical Pathology Resources
Section 7
Metabolic Phenotyping resources
Section 8
Pregnancy, embryo, pup evaluation
   
GIF of 09 course
      For additional Course information or to to order a complete manual, or
to provide feedback or suggestions - contact  Dr. Brayton.

 

 

 

 

 
 
 
 
 

© The Johns Hopkins University, The Johns Hopkins Hospital, and Johns Hopkins Health System. All rights reserved.

Privacy Policy and Disclaimer