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Phenotyping Course Schedule 07
Phenotyping for Functional Genetics, ME:680.712
3rd quarter/2nd semester: January 10- March 8, 2007;
Wednesday & Thursday 2:30pm - 4:00pm
Room: BRB 801; Enrollment limited to 15.
Lecture 9, February 22, 2007
Mikhail Pletnikov, M.D., Ph.D
Psychiatry & Neurobehavioral Sciences
Assessing emotion, learning and memory and social behaviors in rats and mice
PDF of PPT presentation
Bailey, K. R., N. R. Rustay, et al. (2006). "Behavioral phenotyping of transgenic and knockout mice: practical concerns and potential pitfalls." Ilar J 47(2): 124-31.
Crabbe, J. C., D. Wahlsten, et al. (1999). "Genetics of mouse behavior: interactions with laboratory environment." Science 284(5420): 1670-2.Go to Article.
Crawley, J. N. (2000). What's Wrong with My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice. New York, NY, Wiley Liss.
Rogers, D. C., E. M. Fisher, et al. (1997). "Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment." Mamm Genome 8(10): 711-3. Go to Article.
Wahlsten, D., A. Bachmanov, et al. (2006). "Stability of inbred mouse strain differences in behavior and brain size between laboratories and across decades." Proc Natl Acad Sci U S A 103(44): 16364-9. Go to Article.
Wahlsten, D., P. Metten, et al. (2003). "Different data from different labs: lessons from studies of gene-environment interaction." J Neurobiol 54(1): 283-311.
Go To MOUSE PHENOME DATABASE Behavioral Tests and Projects
Selected Publications by Dr. Pletnikov
Pletnikov MV, Rubin SA, Moran TH, Carbone KM. Related Exploring the cerebellum with a new tool: neonatal Borna disease virus (BDV) infection of the rat's brain. Cerebellum. 2003;2(1):62-70. Review.
Carbone KM, Rubin SA, Pletnikov M. Related Articles, Borna disease virus (BDV)-induced model of autism: application to vaccine safety test design. Mol Psychiatry. 2002;7 Suppl 2:S36-7. Review.
Pletnikov MV, Rubin SA, Vogel MW, Moran TH, Carbone KM. Effects of genetic background on neonatal Borna disease virus infection-induced neurodevelopmental damage. II. Neurochemical alterations and responses to pharmacological treatments.Brain Res. 2002 Jul 19;944(1-2):108-23. PMID: 12106671 [PubMed - indexed for MEDLINE]
Pletnikov MV, Rubin SA, Vogel MW, Moran TH, Carbone KM. Effects of genetic background on neonatal Borna disease virus infection-induced neurodevelopmental damage. I. Brain pathology and behavioral deficits. Brain Res. 2002 Jul 19;944(1-2):97-107. PMID: 12106670 [PubMed - indexed for MEDLINE]
Pletnikov MV, Moran TH, Carbone KM. Related Articles, Links Borna disease virus infection of the neonatal rat: developmental brain injury model of autism spectrum disorders.Front Biosci. 2002 Mar 1;7:d593-607. Review. References