Phenotyping Core
Mission:
The Phenotyping core aims to promote functional genomics initiatives at Johns Hopkins by assisting and collaborating in characterization and use of genetically and phenotypically relevant models of disease and gene function, and to enhance understanding and expertise in phenotyping for functional genomics initiatives by:
1) Providing pathology support: a) Clinical pathology (hematology, chemistry, urinalyses, etc. - i.e. 'clinical' specimens from live animals), b) Necropsy (gross/macro-photography, tissue/organ collections, tissue/organ weights, special fixatives), c) Histology, histopathology evlauation
2) Providing training in standard and specialized evaluation techniques:
Who: technicians, graduate students, postdoctoral trainees, interested faculty;
What: standard and specialized specimen collection and evaluation techniques;
Why: better results (e.g. smaller standard deviations) from operators who fully understand and are committed to the project;
3) Helping to coordinate diverse Department of Comparative Medicine (DCM) and JHMI resources in phenotyping efforts: a) Coordinate investigators and their potential models with various resources (e.g. immunohistochemistry, imaging, ophthalmology, neurobehavioral evaluation) that can contribute to phenotype information, b) Coordinate DCM resources to integrate phenotyping into the training program and to promote participation of DCM faculty / staff and trainees in functional genomic initiatives; and
4) Helping to manage diverse submissions and data types in a data base system that will be a) web accessible, b) secure and c) flexible to accomodate change.
Additional Resources
Note: Some of the following forms are in Adobe Acrobat PDF format. If you do not have the Adobe Acrobat viewer, download it free now. Some forms have notes attached, please double click the notes icon to view the contents.
- Introduction
- Recommended Phenotyping Strategies
- Personnel & Faculty
- Tests/Analysis
- Pathology Submission Form
- Suggested References
- Courses/Conferences/Meetings
- Useful Links
