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Home > Molecular & Comparative Pathobiology > Phenotyping Core

2013 Mouse Pathobiology and Phenotyping Short Course

July 15-19, 2013

Short Course & Workshop on Mouse Biology, Pathology, Genetics for Phenotyping and Translational Research
[concurrent with graduate school course ME 680.712]

At Johns Hopkins University School of Medicine, 
Baltimore, MD USA

TARGET AUDIENCE: Scientists, faculty, postdocs, graduate students, veterinarians, pathologists who use or expect to use mice in translational research.

AIMS: To provide information, practical tools and skills essential to the optimal use of mice in translational research. 

FORMAT & TOPICS: 5 day short-course on mouse biology, pathology, genetics, practical and multidisciplinary phenotyping for translational research, including lectures, 3 hands on laboratory session, exhibits, tours, poster session, pathology slide conference.
DVM/VMD RACE approved 36.5 credit hrs.

SYLLABUS:  MOUSE PATHOBIOLOGY & PHENOTYPING MANUAL is the core syllabus material, several sections can be downloaded (free)    
Additional syllabus/lecture material will be uploaded before the course, and provided at the course.

 Pheno symposium logo

Visit Exhibits
9am Monday to
5pm Tuesday.

  Contact Welza1@jhmi.edu for 2013 Exhibit Information
   

2012 EXHIBITORS

 HARLAN LABORATORIES INC

 

JHU REGISTRATION
(Grad Students, Postdocs, Faculty and Staff)
After June 1, call or email for availability of laboratory sessions.
For graduate students and postdocs, this is graduate school course ME:680.712

 NON-JHU REGISTRATION
Early registration (before June 15):
$800 for Lectures + Hands on Laboratory Sessions, $600 for Lectures Only.
After Jun 15: $1,000 for Lectures and Lab Sessions (call or email for availability), 
$800 for Lectures Only.

Contact welza1@jhmi.edu for more information


BWI is the closest airport
BAL is the closest Amtrak station

Local Hotel Information (this course is at the East Baltimore Campus)

Visitor Parking  (McElderry is Closest Garage)

More about JHUSOM course ME680.712
Tuition Remission Course 80026792
Contact us for more information:
cbrayton@jhmi.edu

  Preliminary Program - 2013

Tucker-Davis Technologies

CRC PRESS

ELSEVIER

WILEY BLACKWELL

 JHU CORES

PHENOTYPING CORE

BRB BEHAVIOR CORE

CMOR CENTER FOR METABOLISM AND OBESITY RESEARCH

Multiplex ELISA Core

SAIRP Small Animal Imaging Resource Program

TMA & Immunohistochemistry Core

Transgenic & ES Cell  Core

 

MONDAY
July 15, 2013

INTRODUCTION to Mouse Pathobiology & Phenotyping
+ EXHIBITS + POSTERS

Web Resources; Summary Tables, references  (23 p PDF)

9-10am
Brayton - Introduction to phenotyping, mouse genetics, nomenclature & Famous Mice (16p PDF)
10-11
Brayton - Common Spontaneous Phenotypes and Diseases (non infectious) (10p PDF)
11-12
Watson - Environmental influences on phenotypes 1
What is in your mouse environment? (lectures 1,2 - 18p PDF)
12-1
LUNCH - VISIT EXHIBITS + POSTERS
+ Medical Illustration Art Exhibit
1-2
Watson - Environmental influences on phenotypes 2 
What ELSE can impact your research and phenotypes: Your Surveillance Program ...
2-3
Brayton - Infections & infectious phenotypes that can impact your research (19p PDF)
3-4
Brayton - Immunodeficient Mice - options & challenges (11p PDF)
4-5
Karim - Pathology and Phenotyping GEM intestinal Cancers (7p PDF)
5-7pm
RECEPTION, EXHIBITS & 
POSTER SESSION (Poster Abstracts - PDF)

TUESDAY

GEM & Multidisciplinary Phenotyping
+ EXHIBITS

9-10
Hawkins/Reeves – Making Mice - traditional and new transgenic technologies (6p PDF)
10-11
Doyle / Shaw - Ophthalmic Phenotyping (6p PDF)
11-12
Lauer/May - Auditory/acoustic Phenotyping (5p PDF)
 12-1
LUNCH & Tours - CMOR (metabolic) & BRB Imaging, Behavioral + EXHIBITS + POSTERS
1-2
Potter/Pletnikov – Emotional / Cognitive Phenotyping (6p PDF)
2-3
Aja - Metabolic Phenotypes & Phenotyping (6p PDF)
3-4
Mitzner – Pulmonary/Respiratory Phenotypes & Phenotyping (12p PDF)   
4-530
Pomper - IMAGING for Phenotyping (10p PDF)
Gabrielson - Cardiovascular phenotyping: In vivo functional correlations to pathology (6p PDF)

WEDNESDAY

Practical Phenotyping 1 DOWNLOAD LAB MANUAL - 41p PDF

9-10
Watson - Clinical / Physical Exam - Modified SHIRPA (refer to Lab Manual)
10-11
Brayton - Clinical Pathology - oversimplified (13p PDF)
11-12
Brayton & al - Online & other Resources (refer to web resources - above))
 12-1
LUNCH (on your own) & Tours - CMOR (metabolic) & BRB Imaging, Behavioral
 130-3pm
Watson / Forbes  & al
LAB 1: Clinical Examination (refer to Lab Manual)
 315-5pm
Forbes / Brayton  & al
LAB 2: Clinical Pathology and Specimen collection (refer to Lab Manual)

THURSDAY

Practical Phenotyping 2

9-10
Brayton - Anatomic Pathology Phenotyping - Necropsy (refer to Lab Manual)
10-11
Brayton - Anatomic Pathology Phenotyping - Trimming (refer to Lab Manual)
11-12
Brayton - Microscopic Anatomy & Pathology by
Virtual Microscopy (refer to Lab Manual)
12-1
LUNCH (on your own)
1-4    
Forbes / Brayton et al.
LAB 3: Anatomic Pathology - Necropsy (refer to Lab Manual)
4-6pm
Digital Slide Conference - with refreshments

FRIDAY

Practical Phenotyping 3
Advanced Pathology for Phenotyping & Translational Research

9-11
Forbes / Brayton et al. 
LAB 4: Anatomic Pathology - Trimming (refer to Lab Manual)
11-12
A Meeker - Basic Immunohistochemistry - principles and protocol development (9p PDF)
12-1
LUNCH
1-2
J Ward - Evaluation of Embryonic & Perinatal Lethality In Mice
2-3
D Haines & M Anver - Pathology Core Support for Basic and Translational Research: GEM, Xeno, TMAs and Nano (9p PDF)
3-4T Cornish – digital microscopy, quantitative microscopy for research applications and publication (10p PDF)
5pm
Quizzes Due ! for course ME680.712
TURN in to BRB 851

         

MOUSE PATHOBIOLOGY & PHENOTYPING MANUAL


1st ed. 2009 selected sections available to download here.
Register for this course, or contact Dr. Brayton for updated revisions.
Section 1
Spontaneous Phenotypes and Conditions in
Common Mouse Strains & Stocks
 Section 2 
Infectious Agents and Phenotypes in Mice
Section 3
Mouse Pathology Glossary: Non Neoplastic; Neoplastic
Section 4 
Anatomic Pathology - Necropsy & Trimming Protocol
Section 5 
(Relatively) Non Invasive Phenotyping
Section 6
Clinical Pathology Resources
Section 7
Metabolic Phenotyping Resources
Section 8
Pregnancy, embryo, pup evaluation
 

     

Previous Courses & Symposia


 

More 2013 Course/Lecture Material
    
 

2013 FELASA Practical Pathology Workshop

Practical Pathology Protocol PDF 15 pages

Practical Pathology PPT PDF 15 pages

Sample Submission Forms 3 pages

           

additional 2012 lecture/syllabus material

2012 BSTP WTSI Mouse Models of Disease

Brayton 1-2: Intro Phenotyping and Famous Mice (PDF)
Brayton 3: Infectious Disease Phenotypes (PDF)
Brayton 4: 'Spontaneous Disease' Phenotypes (PDF)
Cardiff: Modelling Cancer in GEM (PDF)

 2012 In vivo preclinical imaging workshop at Johns Hopkins 

Brayton: In vivo Imaging and Pathology for Phenotyping (PDF)
Garrett:  Anesthesia and Clinical Considerations for Small Animal Imaging (PDF)

Brayton 2012 Mouse Cancer Models Lecture

Brayton 2012 Mouse Ageing Models Lectures

 
 

         

Check out Veterinary Pathology's January 2012
Special Focus Issue on Genetically Engineered Mice http://vet.sagepub.com/content/current 

  

 
      For additional Course information or to to order a complete manual, or
to provide feedback or suggestions - contact  Dr. Brayton.
 

 

 

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