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2012 Mouse Pathobiology and Phenotyping Short Course

July 30 - August 3, 2012

Short Course & Workshop on Mouse Biology, Pathology, Genetics for Phenotyping and Translational Research
[concurrent with graduate school course ME 680.712]

At Johns Hopkins University School of Medicine,
Baltimore, MD USA

TARGET AUDIENCE: Scientists, faculty, postdocs, graduate students, veterinarians, pathologists who use or expect to use mice in translational research.

AIMS: To provide information, practical tools and skills essential to the optimal use of mice in translational research.

FORMAT & TOPICS: 5 day short-course on mouse biology, pathology, genetics, practical and multidisciplinary phenotyping for translational research, including lectures, 3 hands on laboratory session, exhibits, tours, poster session, pathology slide conference.
DVM/VMD RACE (renewal pending) 36.5 hrs.

SYLLABUS: MOUSE PATHOBIOLOGY & PHENOTYPING MANUAL is the core syllabus material, several sections can be downloaded (free)
Additional syllabus/lecture material will be uploaded before the course, and provided at the course.

JHU REGISTRATION (Grad Students, Postdocs, Faculty and Staff)
After July 1, call or email for availability of laboratory sessions.
For graduate students and postdocs, this is graduate school course ME:680.712

NON-JHU REGISTRATION
Early registration (before July 1):
$800 for Lectures + Hands on Laboratory Sessions, $600 for Lectures Only.
After July 1: $1,000 for Lectures and Lab Sessions (call or email for availability),
$800 for Lectures Only.

Forms may take a few seconds to load - contact welza1@jhmi.edu if you have any difficulty.

Exhibitors contact welza1@jhmi.edu for more information.

Visit Exhibits
9am Monday to
5pm Tuesday.

2012 EXHIBITORS

HARLAN LABORATORIES INC

CRC PRESS

ELSEVIER

WILEY BLACKWELL

JHU CORES

PHENOTYPING CORE

CMOR CENTER FOR METABOLISM AND OBESITY RESEARCH

BRB BEHAVIOR CORE

SAIRP Small Animal Imaging Resource Program

Go to 2011 program

Contact Welza1@jhmi.edu for Exhibit Information

BWI is the closest airport
BAL is the closest Amtrak station

Local Hotel Information (this course is at the East Baltimore Campus)

Visitor Parking (McElderry is Closest Garage)

More about JHUSOM course ME680.712
Tuition Remission Course 80026792
Contact us for more information:
cbrayton@jhmi.edu

PRELIMINARY 2012 Program

MONDAY
July 30, 2012

INTRODUCTION to Mouse Pathobiology & Phenotyping
+ EXHIBITS + POSTERS

9-10am

Brayton - Introduction to phenotyping, fundamental mouse genetics and biology, mouse and gene nomenclature

10-11

Brayton - Famous Mice & Phenotypes

11-12

Watson - Environmental influences on phenotypes 1
What is in your mouse environment?

12-1

LUNCH - VISIT EXHIBITS + POSTERS

+ Medical Illustration Art Exhibit

1-2

Watson - Environmental influences on phenotypes 2
What ELSE can impact your research and phenotypes: Your Surveillance Program ...

2-3

Brayton - Infections & infectious phenotypes that can impact your research

3-4

Brayton - Immunodeficient Mice - options & challenges

4-5

Karim - Pathology and Phenotyping GEM intestinal Cancers

5-7pm

RECEPTION, EXHIBITS & POSTER SESSION (Poster Abstracts)

TUESDAY

GEM & Multidisciplinary Phenotyping
+ EXHIBITS

9-10

Hawkins/Reeves – Making Mice - traditional and new transgenic technologies

10-11

Doyle - Ophthalmic Phenotyping

11-12

Lauer/May - Auditory/acoustic phenotyping

12-1

LUNCH & Tours - CMOR (metabolic) & BRB Imaging, Behavioral + EXHIBITS + POSTERS

1-2

Pletnikov/Yocum – Emotional / cognitive phenotyping

2-3

Aja - Metabolic Phenotypes & Phenotyping

3-4

Mitzner – Pulmonary/Respiratory Phenotypes & Phenotyping

4-530

Pomper - IMAGING for Phenotyping

Gabrielson - Cardiovascular phenotyping: In vivo functional correlations to pathology

WEDNESDAY

Practical Phenotyping 1

9-10

Watson - Clinical / Physical Exam - Modified SHIRPA

10-11

Brayton - Clinical Pathology - oversimplified

11-12

Brayton & al - Online & other Resources

12-1

LUNCH (on your own) & Tours - CMOR (metabolic) & BRB Imaging, Behavioral

130-3pm

Watson / Forbes & al
LAB 1: Clinical Examination

315-5pm

Forbes / Brayton & al
LAB 2: Clinical Pathology and Specimen collection

THURSDAY

Practical Phenotyping 2

9-10

Brayton - Anatomic Pathology Phenotyping - Necropsy

10-11

Brayton - Anatomic Pathology Phenotyping - Trimming

11-12

Brayton - Microscopic Anatomy & Pathology by
Virtual Microscopy

12-1

LUNCH (on your own)

1-4

Forbes / Brayton et al.

LAB 3: Anatomic Pathology - Necropsy

4-6pm

Digital Slide Conference - with refreshments

FRIDAY

Practical Phenotyping 3
Advanced Pathology for Phenotyping & Translational Research

9-11

Forbes / Brayton et al.
LAB 4: Anatomic Pathology - Trimming

11-12

A Meeker - Basic Immunohistochemistry - principles and protocol development

12-1

LUNCH

1-2

J Ward - Evaluation of Embryos & Pups

2-3

D Haines & M Anver - Pathology Core Support for Basic and Translational Research: GEM, Xeno, and Nano

3-4

T Cornish – digital microscopy, quantitative microscopy for research applications and publication

5pm

Quizzes Due ! for course ME680.712
TURN in to BRB 851

MOUSE PATHOBIOLOGY & PHENOTYPING MANUAL

1st ed. 2009 selected sections available to download here.
Register for this course, or contact Dr. Brayton for updated revisions.

Section 1
Spontaneous Phenotypes and Conditions in
Common Mouse Strains & Stocks

Section 2
Infectious Agents and Phenotypes in Mice

Section 3
Mouse Pathology Glossary: Non Neoplastic; Neoplastic

Section 4
Anatomic Pathology - Necropsy & Trimming Protocol

Section 5
(Relatively) Non Invasive Phenotyping

Section 6
Clinical Pathology Resources

Section 7
Metabolic Phenotyping Resources

Section 8
Pregnancy, embryo, pup evaluation

Previous Courses & Symposia

2011 JHU Short Course

2010 JHU Short Course

2008 ME 680.712 course schedule

2007 ME 680.712course schedule

2012 BSTP WTSI Mouse Models of Disease
Lecture Material

Brayton 1-2: Intro Phenotyping and Famous Mice (PDF)

Brayton 3: Infectious Disease Phenotypes (PDF)

Brayton 4: 'Spontaneous Disease' Phenotypes (PDF)

Cardiff: Modelling Cancer in GEM (PDF)

FYI Check out Veterinary Pathology's January 2012 Special Focus Issue on Genetically Engineered Mice http://vet.sagepub.com/content/current