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Phenotyping Tests and Resources (in vivo testing)

Mouse Pituitary tumor

  For PATHOLOGY tests & information - Go To
 Pathology for Phenotyping and PreClinical Research
(http://www.hopkinsmedicine.org/mcp/PHENOCORE/TESTpath.html)

In vivo & clinical testing in the phenotyping core lab
(submit/schedule requests via iLAB)

Contact

Cost

Specimen/Comments

Initial Clinical / Physical Exam (SHIRPA-type)
$75/hr
Live mice - with 'control' mice cage side, or in lab (pre-terminal);
training is available.
Body Condition (QNMR EchoMRI100)
% lean, fat, water
Nadine Forbes McBean
$75/hr
Live mice in BRB - with 'control' mice,
or specimens
Faxitron Radiography
High Resolution Radiography
Nadine Forbes McBean
$75/hr + $10/film
Specimens or Terminal;
Film can be scanned for image analysis.
Photography - whole animals, or specimens for publication, documentationNadine Forbes McBean$75/hStereomicroscopy up to 10x, Gross and Macro photography - Specify digital format & size.
CBC/Hematology 
Automated CBC (Hemavet 950) + unstained Smear/film
Clinical Pathology Submission FORM - PDF
Nadine Forbes McBean
$12
50ul whole blood concurrent controls are recommended.
See 2016 test Summary PDF
Clinical Chemistry 
(ALB, ALP, ALT, AMY, AST, CA, CHOL, CK, CR, GGT, GLU, HDL, LDH, LDL, TP, TRG, electrolytes etc)
Clinical Pathology Submission FORM - PDF
Nadine Forbes McBean
from $6.50/test
(+$10 to separate serum/ plasma from whole blood)
Serum or plasma at least 60ul - concurrent controls are recommended.
Glucometry (by Accuchek or 1-touch)
Clinical Pathology Submission FORM - PDF
Nadine Forbes McBean
$20/mouse or $50/hr + $3/strip
only ~10ul whole blood from mouse (in lab or cage side)
Training is available
Urinalysis (Specific gravity by refractometer; Glucose, protein, blood by dipstick; sediment by cytospin + microscopy)
Clinical Pathology Submission FORM - PDF
Nadine Forbes McBean$5-25at least 100ul for most tests
See 2016 test Summary PDF

More In Vivo testing at JH

Contact

Cost

Specimen/Comments

Acoustic/auditory PhenotypingDr. Amanda LauerVar**Live mice
Behavioral Assessments
(Mice & Rats)

Dr. M Pletnikov

Var**Live mice in MRB BRB
more at  SoM Behavior Core
Cardiovascular Phenotyping - imaging, ultrasound, ECGDr. Kathleen GabrielsonVar**Live mice
IMAGING by MRI, PET, SPEC, CT, IVIS, Faxitron
Live mice in BRB
(& specimens)
Lung/Respiratory Phenotyping
Live mice
Mass Spectrophtometry and MetabolomicsDr. David GrahamVar**urine, plasma etc - more at 
Center for Resources in Integrative Biology (CRIB)
Metabolic Phenotyping (calorimetry; O2, diet, water, consumption; CO2, urine, fecal output)
Live mice - more at
Centralized Services for Metabolism Research (CSMR)
Pathogen Testing of animals or biological materials
(Serology, Parasitology, Microbiology, PCR)
Var
Additional rodent services: breeding, genotyping, specimen collection
Var
Contact RAR regarding ill mice or other clinical problems
* Optimal specimen procurement, preparation and submission is CRITICAL to achieving valid clinical pathology results.
  • Insufficient or clotted blood specimens are rejected, as theycan damage our equipment and yield misleading results.
  • Contact Nadine Forbes McBean for information and assistance in procuring, handling and submitting specimens.
** Fees vary, and collaborations may be preferred or required