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Courses Offered by the Department of Molecular and Comparative Pathobiology

680.700 One Medicine
Instructors: Dr. Gabrielson, MCP Faculty and others;  Fridays, 1:30-2:30pm during academic year.
Description: One hour seminars by JH faculty and outside guest speakers dealing with naturally occurring diseases of animals that relate to medical research and human disease, and with animal models of human disease.  
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680.701 Comparative Pathobiology & Genetically Engineered Mice
Instructor: TBD. Offered fourth quarter; Even-numbered years. Next offered in 2016, dates and times TBD. Prerequisites: Courses in biology, histology, and physiology or permission from course director.
Description: This is a course in comparative pathology and disease mechanisms for graduate students.  Lecture and laboratory (microscopy) introduction to comparative pathobiology of the major organ systems. Pathology and pathophysiology themes that are shared across many species are covered, particularly those relevant to mouse genetic models and human disease.

680.702 LAM/PATH Integrated Problem Solving (LIPS)
Instructors: Drs. Metcalf Pate and Beck; Offered all quarters; Mondays from 2pm - 4pm in Ross 403.

680.703 Animal Pathology Laboratory
Instructors: Dr. Zink and MCP Faculty;  Offered all quarters. Credit to be arranged. Prerequisite: 680.701, or Pathology 300.600, or their equivalents.
Description: A limited number of persons may serve as prosectors on the animal pathology diagnostic service. This entails responsibility for gross and microscopic examination of diseased animals and tissues submitted for diagnosis by investigators within the institutions, by practicing veterinarians, by the Maryland Zoo in Baltimore, and the National Aquarium in Baltimore. Complete necropsy and histopathology laboratories are available and prosectors work under close faculty supervision. Rotational assignments may vary according to schedules.

680.705 Introductory Course in Large Animal Surgery
Instructor: Dr. Garret.
 Schedule and syllabus vary with specific aims.
Description: For investigators, residents and students to gain expertise in anesthesia and specific procedures, including minimally invasive surgery, open surgery, instrument use and handling, suturing, catheter and/or sheath placement, intubation.

680.710 Clinical Conference in Laboratory Animal Medicine
Instructor: Dr. Adams; Fridays, 9am-10am. Year round in Ross 403.
Description: Weekly conferences in clinical laboratory animal medicine and clinical pathology. Attendance by comparative medicine and comparative pathology fellows is expected. The course is open to all other students, fellows and faculty.

680.711 Comparative Pathology Conference (Slide Conference)
Instructors: Dr. Mankowski and MCP Faculty; Fridays 12-1pm; Year round.  BRB, 8th floor conference room, 801.
Description: This is a weekly one hour diagnostic slide conference focuses on the discussion of histologic and electron microscopic examples of unknown cases drawn from a wide variety of animal species. Cases are available for study during the week preceding the conference. Participants describe the cases, give differential diagnoses, and discuss etiology and pathogenesis with the guidance of faculty members.
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680.712 Phenotyping for Functional Genetics Go to Phenotyping Course home page.
Instructor: Dr. Brayton , Dr. Watson and others; Offered as a 5-day short course in July in 2010, 2011, 2013, 2015 concurrent with the Mouse Pathobiology and Phenotyping Short Course.   (Was offered as a 3rd quarter course 2006-9) 
Description: This course is intended for graduate students or postdocs at any level, who work with, or expect to work with mouse models and genetically engineered mice. It provides information, practical tools and skills essential to the optimal use of mice in translational research. The  5 day short-course on mouse biology, pathology, genetics, practical and multidisciplinary phenotyping for translational research includes >30hr lectures, 3 hands on laboratory sessions (10hr), exhibits, tours, poster session, pathology slide conference.   Phenotyping and preclinical translational science expertise at JHMI are emphasized.

680.713 Regulations that Govern Animal Research
Instructor: Dr. Kelly A. Metcalf Pate Wednesdays from 4pm - 5pm in Ross 403.
Description: Federal legislation dictates how scientists can use animals in research, and is supplemented by a number of guidelines that institutions must follow in order to receive NIH funds.  This course systematically reviews the laws and regulations that govern animal research, and is especially suitable for veterinarians preparing to sit for American College of Laboratory Animal Medicine board exam and for members of the Institutional Animal Care and Use Committee. 

680.802 Journal Club for Laboratory Animal Medicine Board Review
Instructor: Dr. Garret; Tuesdays, 4pm-5pm; Ross 403

187.620 (SPH) Toxicological Pathology 
Instructor: Dr. Gabrielson and others; Wednesdays and Fridays 3:00-4:50, Offered even-numbered years. 
Description: Focuses on pathophysiology and pathologic responses of toxicity induced by toxins of the cardiovascular, pulmonary, reproductive, neurological, immune, and gastrointestinal systems. A review of normal histology for the specific organ systems is compared to examples of acute and chronic toxicity to illustrate light microscopic and ultrastructural damage with correlation to altered physiology and function. The course integrates into each organ system studied a review of standard techniques used in toxicity studies including the use of animal necropsy, histology/pathology, various tissue molecular biological techniques, transgenic mice, and noninvasive physiological monitoring.

300.713 Pathology for Graduate Students: Basic Mechanisms
Dr. Gabrielson & others; Offered Fall semester, Monday, Wednesday, Friday

Phenotyping and Comparative Pathology Tuesday PM slide conference
Instructor: Dr. Braytonmonthly slide conference, Summer months Tuesday 4-6pm 801 MRB. 
Description: interactive, case/slide conference; emphasizes recent cases within and beyond JHU.  Interesting cases and glass slides welcome! More information at

Veterinary Pathology Mock Exam
Instructor: Dr. Gabrielson and others - contact Contact Dr. Gabrielson for more information, to contribute or to participate.
Participating institutions have included: AFIP, NC state; Penn State, UPenn, Vtech
Description: 1- day format including: Histopathology (written), Gross Pathology (written), General Pathology (multiple guess), Clinical Pathology (multiple guess), Veterinary Pathology (multiple guess), in a highly collegial setting.