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Welcome

Our Mission

The Department of Molecular and Comparative Pathobiology (MCP) provides leadership in biomedical research on animal and human diseases and ensures the health and humane care of research animals within the institution.

Our Interim DirectorZink
M. Christine Zink  DVM,PhD, DACVP.
Dr. Zink  studies animal models of HIV infection. continued

Lab Animal and Pathology Residency Training Programs


Lab Animal and Pathology Postdoctoral Fellowships


Retrovirus Laboratory Doctoral and Postdoctoral Fellowships

Our History

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Upcoming Events

Tuesday, February 19, 2008 
2008 Johns Hopkins Phenotyping
Symposium III

Tilghman Auditorium/Turner Concourse
720 Rutland Avenue,Baltimore, MD 21205
Phenotyping Symposium Website

All welcome. Registration FREE but Required. Contact: Amanda Holmes  aholme10@jhmi.edu 


Departmental Calendar 


Grant Spotlight  

Andy McCallion

Andrew McCallion was awarded an
"Exploratory Research Grant for Basic and Translational Stem Cell Research
in Support of Medical Therapies"
by the Maryland Stem Cell Research Fund 
for  $200K over the next two years.
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Faculty Publications
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Chase AJ, Sedaghat AR, German JR, Gama L, Zink MC, Clements JE, Siliciano RF. Severe depletion of CD4+ CD25+ regulatory T cells from the intestinal lamina propria but not peripheral blood or lymph nodes during acute simian immunodeficiency virus infection. J Virol. 2007 Dec;81(23):12748-57. Epub 2007 Sep 12. PMID: 17855517

Syversen E, Pineda FJ, Watson J. Temperature Variations Recorded during Interinstitutional Air Shipments of Laboratory Mice. JAALAS Vol 47(1) :31-36. Jan 2008.

Scorpio DG, Leutenegger C, Berger J, Barat N, Madigan JE, Dumler JS. Sequential analysis of A. phagocytophilum msp2 transcription in murine and equine models of human granulocytic anaplasmosis. Clin Vaccine Immunol. 2007 Dec 19; [Epub ahead of print] PMID: 18094110

Morrell CN, Sun H, Swaim AM, Baldwin WM 3rd. Platelets an inflammatory force in transplantation. Am J Transplant. 2007 Nov;7(11):2447-54. PMID: 17927608
 

Loeffer I, Howard J, Montali RJ, Hayek L, Dubovi E, Zhang Z, Yan Q, Guo W, Wildt D. Serosurvey of Ex Situ Giant Pandas (Ailuropoda Melanoleuca) and Red Pandas (Ailurus Fulgens) In China With Implications for Species Conservation. Journal of Zoo and Wildlife Medicine. 2007 Dec; 38(4):559-566

Osburn WO, Karim B, Dolan PM, Liu G, Yamamoto M, Huso DL, Kensler TW. Increased colonic inflammatory injury and formation of aberrant crypt foci in Nrf2-deficient mice upon dextran sulfate treatment. Int J Cancer. 2007 Nov 1;121(9):1883-91. PMID: 17631644

Magno P, Giday SA, Dray X, Chung SS, Cotton PB, Gostout CJ, Hawes RH, Kalloo AN, Pasricha PJ, White JJ, Assumpcao L, Marohn MR, Gabrielson KL, Kantsevoy SV. A new stapler-based full-thickness transgastric access closure: results from an animal pilot trial. Endoscopy. 2007 Oct;39(10):876-80. PMID: 17968803

Scorpio DG, Ruben DS, Liao Z, Hildreth JE, Fletcher CA.  2008. Cervicovaginal evaluation in macaques used as a model for topical microbicide safety studies.  Journal Medical Primatology, Volume 265

Li T, Wen H, Brayton C, Das P, Smithson LA, Fauq A, Fan X, Crain BJ, Price DL, Golde TE, Eberhart CG, Wong PC. Epidermal growth factor receptor and notch pathways participate in the tumor suppressor function of gamma-secretase. J Biol Chem. 2007 Nov 2;282(44):32264-73. Epub 2007 Sep 7. PMID: 17827153

Chen MK, Kuwabara H, Zhou Y, Adams RJ, Braši? JR, McGlothan JL, Verina T, Burton NC, Alexander M, Kumar A, Wong DF, Guilarte TR. VMAT2 and dopamine neuron loss in a primate model of Parkinson's disease. J Neurochem. 2007 Nov 7; [Epub ahead of print] PMID: 17988241

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