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Prostate Cancer

Prostate cancer is the most common cancer diagnosed in men and the second leading cause of cancer death in men.  With a research portfolio that encompasses nearly all of the prostate cancer research done at Johns Hopkins, our Prostate Cancer Program research team is focused on all aspects of the disease; from the unique biology of this cancer to improved screening and prevention strategies, diagnostic methods, and therapies that target the specific cellular mechanisms involved in the initiation and progression of prostate cancer.  Our investigators have uncovered new biomarkers of prostate cancer and cellular alterations that serve as therapeutic targets and allow physicians to determine which therapies will be most effective for each individual patient.  Investigators also are studying environmental factors, such as diet, inflammation, and immunity, as well as genetic determinants, such as methylation, hormone function and DNA damage repair mechanisms, which put men at risk for prostate cancer.  The Program Leaders are Kenneth Pienta, M.D., Sam Denmeade, M.D., Shawn Lupold, Ph.D.


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