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Title:
IMAGE Study: Individualized Molecular Analyses Guide Efforts in Breast Cancer – Personalized Molecular Profiling in Cancer Treatment at Johns Hopkins
Protocol Number:
J12129
Phase:
Pilot
Physician:
Vered Stearns
Purpose:
There has been much interest in the development of personalized therapy for cancer. The purpose of this research study is to find out if we can create a personalized genetic signature of your tumor and use this individualized genetic information to suggest treatments.
Eligibility:
Patients with metastatic breast cancer that is triple negative (does not express the estrogen or progesterone, and does not overexpress HER2). Patients need to have received at least one prior treatment with chemotherapy.
Treatment:
Your tumor specimen will be reviewed by the pathology department at Johns Hopkins and will also be sent to Foundation Medicine (a company with whom we are collaborating on this study) for genetic testing. The blood will be analyzed to look for genetic similarities with the tumor sample.Once all the genetic test results are back, a group of experts will meet to review the information. If possible, we will come up with suggested strategies for therapy. These suggestions will be shared with you and your doctor. We will also inform you if there was any problem analyzing your tissue or if we do not find any genes to make treatment suggestions. You and your doctor will independently decide whether to be treated based on the study teamâ??s suggestion. As part of the study, we would like to follow you through your future treatments and will request that you have research blood samples and complete questionnaires when changing therapy.
Population:
Adult
Last Update
07/14/2014 04:02 AM
 

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