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Scientists at the Johns Hopkins Kimmel Cancer Center have deciphered the genetic code for medulloblastoma, the most common pediatric brain cancer and a leading killer of children with cancer. The genetic "map" is believed to be the first reported of a pediatric cancer genome and is published online in the Dec. 16 issue of Science Express.
In a proof of principal study in mice, scientists at Johns Hopkins and the Virginia Commonwealth University (VCU) have shown that a set of genetic instructions encased in a nanoparticle can be used as an “ignition switch” to rev up gene activity that aids cancer detection and treatment.
A gene target for drug resistance, a triple-drug cocktail for triple negative breast cancer, and patients’ risk for carpal tunnel syndrome are among study highlights scheduled to be presented by Johns Hopkins Kimmel Cancer Center scientists during the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium, held Dec. 8-12.
Scientists at Johns Hopkins have identified a compound that could be used to starve cancers of their sugar-based building blocks. The compound, called a glutaminase inhibitor, has been tested on laboratory-cultured, sugar-hungry brain cancer cells and, the scientists say, may have the potential to be used for many types of primary brain tumors.
Scientists at the Johns Hopkins Kimmel Cancer Center, University of Helsinki and Stanford University have developed a technique to keep normal and cancerous prostate tissue removed during surgery alive and functioning normally in the laboratory for up to a week.
Each time you check out your groceries at your local Safeway supermarket, you have a chance to help women in the fight against breast cancer.
During October, Safeway customers in Baltimore and throughout Maryland can donate $1 or more, which will be added to their order at checkout stands, as part of Safeway’s annual campaign to support breast cancer research at the Johns Hopkins Kimmel Cancer Center.
Pancreatic cancer develops and spreads much more slowly than scientists have thought, according to new research from Johns Hopkins investigators. The finding indicates that there is a potentially broad window for diagnosis and prevention of the disease.
John Groopman, Ph.D., associate director of cancer prevention and control at the Johns Hopkins Kimmel Cancer Center and the Anna M. Baetjer Professor and Chair of the Department of Environmental Health Sciences at the Johns Hopkins Bloomberg School of Public Health, is the recipient of the Award for Excellence in Cancer Prevention Research from the American Association for Cancer Research (AACR) and the Prevent Cancer Foundation.
Using a computer program, researchers from Johns Hopkins have predicted which changes in the DNA code may cause pancreatic cells to become cancerous and deadly. The investigators say the findings could lead to more focused studies on better ways to treat the disease, which has only a 5 percent survival rate five years after diagnosis.
After an international search, Vered Stearns, M.D., has been named Co-Director of the Johns Hopkins Kimmel Cancer Center’s Breast Cancer Program.
A protein that pumps calcium out of cells also moonlights as a signal to get massive quantities of the stuff to flow in, according to Johns Hopkins scientists. Their discovery of this surprisingly opposite function, reported Oct. 1 in Cell, highlights the link between calcium and cancer and holds the promise of a new therapeutic target for certain breast cancers.
Scientists at the Johns Hopkins Kimmel Cancer Center have identified two genes whose mutations appear to be linked to ovarian clear cell carcinoma, one of the most aggressive forms of ovarian cancer. Clear cell carcinoma is generally resistant to standard therapy.
Johns Hopkins researchers working on mice have discovered a protein that is a major target of a gene that, when mutated in humans, causes tumors to develop on nerves associated with hearing, as well as cataracts in the eyes.
Patients with a certain type of scleroderma may get cancer and scleroderma simultaneously, Johns Hopkins researchers have found, suggesting that in some diseases, autoimmunity and cancer may be linked.
Swim Across America (SAA), the national non-profit organization dedicated to raising money and awareness for cancer research, prevention and treatment through swimming-related events around the country, held its first swims in the Baltimore-area on Sunday, September 19 at 8 AM with an open water swim starting from the Waltjen Shedlick Farm in Gibson Island Harbor and a pool swim at the Meadowbrook Aquatic and Fitness Center in Mount Washington.
June 11, 2010 - Johns Hopkins Kimmel Cancer Center has been awarded the largest gift for pancreas cancer research in its history. The award was made possible by Albert P. “Skip” Viragh, Jr., a mutual fund leader, and a pancreas cancer patient treated at Johns Hopkins. He died of the disease at age 62.
Call for Submissions Guitar Art Benefit Showcase & Auction Daniel Stuelpnagel, Curator
The Johns Hopkins Sidney Kimmel Comprehensive Cancer Center continues for the 11th year with Paul Reed Smith Guitars for a national charity weekend October 2-4th to benefit the Living with Cancer Resource Program at Johns Hopkins. The Johns Hopkins’ Living with Cancer Resource Program offers patients, families and caregivers a variety of support groups, educational workshops and programs designed to teach patients and their families how to manage the realities of cancer - free of charge.
These news tips are based on abstracts and presentations by Johns Hopkins Kimmel Cancer Center scientists at the annual meeting of the American Society of Clinical Oncology, June 4-8, in Chicago.
Johns Hopkins Medicine and the University of Maryland Medical Center have joined forces to expand regional access to their prominent radiation oncology programs, and to provide cancer patients with state-of-the-art, comprehensive outpatient radiation therapy services at a conveniently located community practice in Howard County.
A national network of cancer researchers have identified a common set of molecular changes in some forms of the deadly brain tumor glioma that indicate a patient is likely to have a more favorable outcome.
Guide to News from Johns Hopkins Scientists at the American Association for Cancer Research Meeting
Thomas Kensler, Ph.D., professor in the Environmental Health Sciences and a renowned cancer researcher at the Johns Hopkins Kimmel Cancer Center and Johns Hopkins Bloomberg School of Public Health, received the 16th annual American Association for Cancer Research-American Cancer Society Award for Research Excellence in Cancer Epidemiology and Prevention.
A protein discovered in fruit fly eyes has brought a Johns Hopkins team closer to understanding how the human heart and other organs automatically "right size" themselves, a piece of information that may hold clues to controlling cancer.
Information falsely attributed to Johns Hopkins called, "CANCER UPDATE FROM JOHN HOPKINS" describes properties of cancer cells and suggests ways of preventing cancer. Johns Hopkins did not publish the information, which often is an email attachment, nor do we endorse its contents.
Two-time breast cancer survivor and Johns Hopkins administrator, Lillie Shockney, RN, BS, MAS was inducted into the 25th Maryland Women’s Hall of Fame by the Maryland Commission for Women, during a ceremony on March 18.
Johns Hopkins Kimmel Cancer Center scientists have found a set of "master switches" that keep adult blood-forming stem cells in their primitive state. Unlocking the switches' code may one day enable scientists to grow new blood cells for transplant into patients with cancer and other bone marrow disorders.
Working with mice, Johns Hopkins scientists who tested drugs intended to halt growth of brain cancer stem cells – a small population of cells within tumors that perpetuate cancer growth – conclude that blocking these cells may be somewhat effective, but more than one targeted drug attack may be needed to get the job done.
Scientists at the Johns Hopkins Kimmel Cancer Center have used data from the whole genome sequencing of cancer patients to develop individualized blood tests they believe can help physicians tailor patients' treatments. The genome-based blood tests, believed to be the first of their kind, may be used to monitor tumor levels after therapy and determine cancer recurrence.
JOHNS HOPKINS RESEARCHERS SAY VACCINE APPEARS TO “MOP UP” LEUKEMIA CELLS GLEEVEC LEAVES BEHIND
Promise and Progress
The magazine of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.
A publication by the Department of Radiation Oncology and Molecular Radiation Sciences of the Johns Hopkins School of Medicine.
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