Skip Navigation
 
 
 
 
 
Print This Page
Share this page: More
 

Hormone Therapy Combined with Chemotherapy Increases Survival for Prostate Cancer Patients

December, 2013

Early results from a study funded by the National Institutes of Health (NIH) have shown that men with hormone-sensitive metastatic prostate cancer who have received a combination of the chemotherapy drug docetaxel and hormone therapy lived longer than patients who received hormone therapy alone.

The study enrolled 790 men with metastatic prostate cancer who received a form of hormone therapy known as ADT (androgen deprivation therapy). ADT reduces the levels of male hormones called androgens, which can stimulate prostate cancer cells. In addition to the hormone therapy, some men received docetaxel. Sixty-nine percent of men who received the combo chemo and hormone therapy were alive at three years compared with 52.5 percent of men who received hormone therapy alone.

Johns Hopkins Kimmel Cancer Center expert, Michael Carducci, M.D., is the Genitourinary Cancers Chair for the ECOG-ACRIN who, in collaboration with SWOG, Alliance for Clinical Trials in Oncology and NRG Oncology designed and conducted the trial known as E3805.

Further follow-up will be performed on patients with less extensive metastatic disease who participated in E3805 in order to define the effect of this treatment combination on these patients.

More information
 

 

Read Our Blogs
Cancer Matters: timely topics
Our Cancer: for caregivers

 

Chemo School & Virtual Tour

Take our video class to learn about your first steps in receiving chemotherapy Chemo School
Prepare for your first visit with this "walking" tour of our clinical facilities.  Watch the video.
 

Publications

Promise and Progress
The magazine of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

On Target
A publication by the Department of Radiation Oncology and Molecular Radiation Sciences of the Johns Hopkins School of Medicine.

 

The Kimmel Wire

The Kimmel Wire

Latest News from the Kimmel Cancer Center
Subscribe Now

Traveling for care?

blue suitcase

Whether crossing the country or the globe, we make it easy to access world-class care at Johns Hopkins.

Maryland 410-955-5222
U.S. 410-955-5222
International +1-410-614-6424

NCI CCC

 
 
 
 
 

© The Johns Hopkins University, The Johns Hopkins Hospital, and Johns Hopkins Health System. All rights reserved.