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Kristine Glunde

Ph.D.
Interests

Radiology and Radiological Sciences

Titles

Associate Professor

Journal Citations

Glunde, K.; Ackerstaff, E.; Mori, N.; Jacobs, M.A.; Bhujwalla, Z.M. Choline phospholipid metabolism in cancer: consequences for molecular pharmaceutical interventions. Molecular pharmaceutics. 2006 Sep-Oct;3(5):496-506.

Glunde, K.; Jacobs, M.A.; Bhujwalla, Z.M. Choline metabolism in cancer: implications for diagnosis and therapy. Expert review of molecular diagnostics. 2006 Nov;6(6):821-829.

Glunde, K.; Jie, C.; Bhujwalla, Z.M. Mechanisms of indomethacin-induced alterations in the choline phospholipid metabolism of breast cancer cells. Neoplasia. 2006 Sep;8(9):758-771.

Glunde, K.; Serkova, N.J. Therapeutic targets and biomarkers identified in cancer choline phospholipid metabolism. Pharmacogenomics. 2006 Oct;7(7):1109-1123.

Li, C.; Greenwood, T.R.; Bhujwalla, Z.M.; Glunde, K. Synthesis and characterization of glucosamine-bound near-infrared probes for optical imaging. Org Lett. 2006 Aug 17;8(17):3623-3626.

Glunde, K.; Bhujwalla, Z.M. Choline kinase alpha in cancer prognosis and treatment. Lancet Oncol. 2007 Oct;8(10):855-857.

Glunde, K.; Pathak, A.P.; Bhujwalla, Z.M. Molecular-functional imaging of cancer: to image and imagine. Trends in molecular medicine. 2007 Jul;13(7):287-297.

Mori, N.; Glunde, K.; Takagi, T.; Raman, V.; Bhujwalla, Z.M. Choline kinase down-regulation increases the effect of 5-fluorouracil in breast cancer cells. Cancer Res. 2007 Dec 1;67(23):11284-11290.

Raman, V.; Pathak, A.P.; Glunde, K.; Artemov, D.; Bhujwalla, Z.M. Magnetic resonance imaging and spectroscopy of transgenic models of cancer. NMR Biomed. 2007 May;20(3):186-199.
Stasinopoulos, I.; O'Brien, D.R.;

Wildes, F.; Glunde, K.; Bhujwalla, Z.M. Silencing of cyclooxygenase-2 inhibits metastasis and delays tumor onset of poorly differentiated metastatic breast cancer cells. Mol Cancer Res. 2007 May;5(5):435-442.

Glunde, K.; Bhujwalla, Z.M. Will magnetic resonance imaging (MRI)-based contrast agents for molecular receptor imaging make their way into the clinic? Journal of Cellular and Molecular Medicine. 2008 Jan-Feb;12(1):187-188.

Glunde, K.; Shah, T.; Winnard, P.T., Jr.; Raman, V.; Takagi, T.; Vesuna, F.; Artemov, D.; Bhujwalla, Z.M. Hypoxia regulates choline kinase expression through hypoxia-inducible factor-1 alpha signaling in a human prostate cancer model. Cancer Res. 2008 Jan 1;68(1):172-180.

Li, C.; Greenwood, T.R.; Glunde, K. Glucosamine-bound near-infrared fluorescent probes with lysosomal specificity for breast tumor imaging. Neoplasia. 2008 Apr;10(4):389-398.

Penet, M.F.; Glunde, K.; Jacobs, M.A.; Pathak, A.P.; Bhujwalla, Z.M. Molecular and functional MRI of the tumor microenvironment. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2008 May;49(5):687-690.

Glunde, K.; Jacobs, M.A.; Pathak, A.P.; Artemov, D.; Bhujwalla, Z.M. Molecular and functional imaging of breast cancer. NMR Biomed. 2009 Jan;22(1):92-103.

Glunde, K.; Stasinopoulos, I. ADAM17: the new face of breast cancer-promoting metalloprotease activity. Cancer Biol Ther. 2009 Jun;8(11):1055-1057.

Krishnamachary, B.; Glunde, K.; Wildes, F.; Mori, N.; Takagi, T.; Raman, V.; Bhujwalla, Z.M. Noninvasive detection of lentiviral-mediated choline kinase targeting in a human breast cancer xenograft. Cancer Res. 2009 Apr 15;69(8):3464-3471.

Nimmagadda, S.; Glunde, K.; Pomper, M.G.; Bhujwalla, Z.M. Pharmacodynamic markers for choline kinase down-regulation in breast cancer cells. Neoplasia. 2009 May;11(5):477-484.

Serkova, N.J.; Glunde, K. Metabolomics of cancer. Methods Mol Biol. 2009;520:273-295.

Amstalden van Hove, E.R.; Blackwell, T.R.; Klinkert, I.; Eijkel, G.B.; Heeren, R.M.; Glunde, K. Multimodal mass spectrometric imaging of small molecules reveals distinct spatio-molecular signatures in differentially metastatic breast tumor models. Cancer Res. 2010 Nov 15;70(22):9012-9021.

Glunde, K.; Artemov, D.; Penet, M.F.; Jacobs, M.A.; Bhujwalla, Z.M. Magnetic resonance spectroscopy in metabolic and molecular imaging and diagnosis of cancer. Chem Rev. 2010 May 12;110(5):3043-3059.

Iorio, E.; Ricci, A.; Bagnoli, M.; Pisanu, M.E.; Castellano, G.; Di Vito, M.; Venturini, E.; Glunde, K.; Bhujwalla, Z.M.; Mezzanzanica, D.; Canevari, S.; Podo, F. Activation of phosphatidylcholine cycle enzymes in human epithelial ovarian cancer cells. Cancer Res. 2010 Mar 1;70(5):2126-2135.

Kakkad, S.M.; Solaiyappan, M.; O'Rourke, B.; Stasinopoulos, I.; Ackerstaff, E.; Raman, V.; Bhujwalla, Z.M.; Glunde, K. Hypoxic tumor microenvironments reduce collagen I fiber density. Neoplasia. 2010 Aug;12(8):608-617.

Penet, M.F.; Mikhaylova, M.; Li, C.; Krishnamachary, B.; Glunde, K.; Pathak, A.P.; Bhujwalla, Z.M. Applications of molecular MRI and optical imaging in cancer. Future Med Chem. 2010 Jun;2(6):975-988.

Shah, T.; Wildes, F.; Penet, M.F.; Winnard, P.T., Jr.; Glunde, K.; Artemov, D.; Ackerstaff, E.; Gimi, B.; Kakkad, S.; Raman, V.; Bhujwalla, Z.M. Choline kinase overexpression increases invasiveness and drug resistance of human breast cancer cells. NMR Biomed. 2010 Jul;23(6):633-642.

 

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