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Dr. Jonathan Schneck

M.D., Ph.D.



Professor of Pathology, Medicine and Oncology


M.D./Ph.D., Albert Einstein College of Medicine (Immunology, Pediatrics)


Resident, Children's Hospital, Washington, D.C.
Medical Staff, National Institute of Allergey and Infectious Diseases (Immunology)
Fellow, National Institutes of Health

Journal Citations

Mohamood, A.S.; Trujillo, C.J.; Zheng, D.; Jie, C.; Murillo, F.M.; Schneck, J.P.; Hamad, A.R. Gld mutation of Fas ligand increases the frequency and up-regulates cell survival genes in CD25+CD4+ TR cells. International immunology. 2006 Aug;18(8):1265-1277.

Deviren, G.; Gupta, K.; Paulaitis, M.E.; Schneck, J.P. Detection of antigen-specific T cells on p/MHC microarrays. J Mol Recognit. 2007 Jan-Feb;20(1):32-38.

Fahmy, T.M.; Schneck, J.P.; Saltzman, W.M. A nanoscopic multivalent antigen-presenting carrier for sensitive detection and drug delivery to T cells. Nanomedicine. 2007 Mar;3(1):75-85.

Mohamood, A.S.; Guler, M.L.; Xiao, Z.; Zheng, D.; Hess, A.; Wang, Y.; Yagita, H.; Schneck, J.P.; Hamad, A.R. Protection from autoimmune diabetes and T-cell lymphoproliferation induced by FasL mutation are differentially regulated and can be uncoupled pharmacologically. Am J Pathol. 2007 Jul;171(1):97-106.

Schutz, C.; Fleck, M.; Mackensen, A.; Zoso, A.; Halbritter, D.; Schneck, J.P.; Oelke, M. Killer artificial antigen-presenting cells: a novel strategy to delete specific T cells. Blood. 2008 Apr 1;111(7):3546-3552.

Shaikh, S.R.; Mitchell, D.; Carroll, E.; Li, M.; Schneck, J.; Edidin, M. Differential effects of a saturated and a monounsaturated fatty acid on MHC class I antigen presentation. Scandinavian journal of immunology. 2008 Jul;68(1):30-42.

Tao, S.C.; Li, Y.; Zhou, J.; Qian, J.; Schnaar, R.L.; Zhang, Y.; Goldstein, I.J.; Zhu, H.; Schneck, J.P. Lectin microarrays identify cell-specific and functionally significant cell surface glycan markers. Glycobiology. 2008 Oct;18(10):761-769.

Webb, T.J.; Giuntoli, R.L., 2nd; Rogers, O.; Schneck, J.; Oelke, M. Ascites specific inhibition of CD1d-mediated activation of natural killer T cells. Clin Cancer Res. 2008 Dec 1;14(23):7652-7658.

Durai, M.; Krueger, C.; Ye, Z.; Cheng, L.; Mackensen, A.; Oelke, M.; Schneck, J.P. In vivo functional efficacy of tumor-specific T cells expanded using HLA-Ig based artificial antigen presenting cells (aAPC). Cancer Immunol Immunother. 2009 Feb;58(2):209-220.

Mertens, J.; Fabri, M.; Zingarelli, A.; Kubacki, T.; Meemboor, S.; Groneck, L.; Seeger, J.; Bessler, M.; Hafke, H.; Odenthal, M.; Bieler, J.G.; Kalka, C.; Schneck, J.P.; Kashkar, H.; Kalka-Moll, W.M. Streptococcus pneumoniae serotype 1 capsular polysaccharide induces CD8CD28 regulatory T lymphocytes by TCR crosslinking. PLoS Pathog. 2009 Sep;5(9):e1000596.

Ndhlovu, Z.M.; Angenendt, M.; Heckel, D.; Schneck, J.P.; Griffin, D.E.; Oelke, M. Development of an artificial-antigen-presenting-cell-based assay for the detection of low-frequency virus-specific CD8(+) T cells in whole blood, with application for measles virus. Clin Vaccine Immunol. 2009 Jul;16(7):1066-1073.

Shiratsuchi, T.; Schneck, J.; Kawamura, A.; Tsuji, M. Human CD1 dimeric proteins as indispensable tools for research on CD1-binding lipids and CD1-restricted T cells. J Immunol Methods. 2009 Jun 30;345(1-2):49-59.

Ugel, S.; Zoso, A.; De Santo, C.; Li, Y.; Marigo, I.; Zanovello, P.; Scarselli, E.; Cipriani, B.; Oelke, M.; Schneck, J.P.; Bronte, V. In vivo administration of artificial antigen-presenting cells activates low-avidity T cells for treatment of cancer. Cancer Res. 2009 Dec 15;69(24):9376-9384.

Webb, T.J.; Bieler, J.G.; Schneck, J.P.; Oelke, M. Ex vivo induction and expansion of natural killer T cells by CD1d1-Ig coated artificial antigen presenting cells. J Immunol Methods. 2009 Jul 31;346(1-2):38-44.

Ndhlovu, Z.M.; Oelke, M.; Schneck, J.P.; Griffin, D.E. Dynamic regulation of functionally distinct virus-specific T cells. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3669-3674.

Oelke, M.; Schneck, J.P. Overview of a HLA-Ig based "Lego-like system" for T cell monitoring, modulation and expansion. Immunol Res. 2010 Jul;47(1-3):248-256.

Schutz, C.; Oelke, M.; Schneck, J.P.; Mackensen, A.; Fleck, M. Killer artificial antigen-presenting cells: the synthetic embodiment of a 'guided missile'. Immunotherapy. 2010 Jul;2(4):539-550.

Yue, C.; Oelke, M.; Paulaitis, M.E.; Schneck, J.P. Novel cellular microarray assay for profiling T-cell peptide antigen specificities. J Proteome Res. 2010 Nov 5;9(11):5629-5637.


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