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Dr. Franck Housseau


Research Associate
Division of Immunology/hematopoiesis
Departments of Oncology


1992-1997 PhD Immunology Denis Diderot University of Paris VII, France PhD conferred March, 1997 1990-1995 National diploma of Pharnacy Rene Descartes University of Paris V, France Pharm.D conferred September, 1995


1992-1997 Clinical biology residency
Department of Immunology and Hematology
Gustave Roussy Cancer institute, Villejuif, France

Post-doctoral fellowships
2001-2002 Division Immunology/Hematopoiesis, Johns Hopkins University School of Medicine, Baltimore, MD; Advisor, D. Pardoll, M.D., Ph.D.

1997-2001 Surgery Branch, National Cancer Institute, National Institutes of Health,
Bethesda, MD; Advisor, S. Topalian, M.D.

Journal Citations

Chan, C.W.; Crafton, E.; Fan, H.N.; Flook, J.; Yoshimura, K.; Skarica, M.; Brockstedt, D.; Dubensky, T.W.; Stins, M.F.; Lanier, L.L.; Pardoll, D.M.; Housseau, F. Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity. Nat Med. 2006 Feb;12(2):207-213.

Harris, T.J.; Grosso, J.F.; Yen, H.R.; Xin, H.; Kortylewski, M.; Albesiano, E.; Hipkiss, E.L.; Getnet, D.; Goldberg, M.V.; Maris, C.H.; Housseau, F.; Yu, H.; Pardoll, D.M.; Drake, C.G. Cutting edge: An in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity. J Immunol. 2007 Oct 1;179(7):4313-4317.

Pletneva, M.; Fan, H.; Park, J.J.; Radojcic, V.; Jie, C.; Yu, Y.; Chan, C.; Redwood, A.; Pardoll, D.; Housseau, F. IFN-producing killer dendritic cells are antigen-presenting cells endowed with T-cell cross-priming capacity. Cancer Res. 2009 Aug 15;69(16):6607-6614.

Rhee, K.J.; Wu, S.; Wu, X.; Huso, D.L.; Karim, B.; Franco, A.A.; Rabizadeh, S.; Golub, J.E.; Mathews, L.E.; Shin, J.; Sartor, R.B.; Golenbock, D.; Hamad, A.R.; Gan, C.M.; Housseau, F.; Sears, C.L. Induction of persistent colitis by a human commensal, enterotoxigenic Bacteroides fragilis, in wild-type C57BL/6 mice. Infect Immun. 2009 Apr;77(4):1708-1718.

Wu, S.; Rhee, K.J.; Albesiano, E.; Rabizadeh, S.; Wu, X.; Yen, H.R.; Huso, D.L.; Brancati, F.L.; Wick, E.; McAllister, F.; Housseau, F.; Pardoll, D.M.; Sears, C.L. A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nat Med. 2009 Sep;15(9):1016-1022.

Housseau, F.; Sears, C.L. Enterotoxigenic Bacteroides fragilis (ETBF)-mediated colitis in Min (Apc+/-) mice: a human commensal-based murine model of colon carcinogenesis. Cell Cycle. 2010 Jan 1;9(1):3-5.


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