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Sarcoma Program

Musculoskeletal tumors are cancers that occur in the muscles, bones or tendons. These cancers can be challenging to treat – recurrences are common and these tumors are very rare. Children with these tumors generally require coordinated care from a variety of experts, including surgeons and medical and radiation oncologists.

The Musculoskeletal Tumor Program at the Johns Hopkins Kimmel Cancer Center in Baltimore provides comprehensive, multidisciplinary care to all children diagnosed with these tumors. Every child seen by our program will have his or her case reviewed and discussed at our weekly multidisciplinary tumor conference, attended by subspecialists from the following groups:

  • Pediatric Oncology
  • Pediatric Surgery
  • Orthopedic Oncology
  • Radiation Oncology
  • Medical Oncology
  • Pathology experts in sarcoma
  • Radiology experts in sarcoma
  • Otolaryngology
  • Neurosurgery

The care and management of each child is discussed in depth, allowing the group to formulate a comprehensive treatment plan tailored to address each child’s age, tumor type and location, and to coordinate the complex care children with sarcoma require. This approach maximizes the chance of cure and minimizes the degree of long-term side effects. Our sarcoma experts also are part of the Johns Hopkins Sarcoma Center, where they work closely with specialists who treat the disease in adult patients. This ensures a seamless transition and state-of-the-art care for teens and young adults with these tumors.

Hear Dr. David Loeb, Director of the Musculoskeletal Tumor Program, Discuss Childhood Sarcomas

Read more about sarcomas common in children, including Ewing’s sarcoma, osteogenic sarcoma, rhabdomyosarcoma.  As members of the Johns Hopkins Sarcoma Center, our experts are well-versed in many more types of rare bone and soft tissue tumors.

Make An Appointment

To make an appointment, please call our referral coordinator at 443-287-6997.

Physicians calling after hours or on weekends may call the Hopkins Access Line (HAL) 24 hours a day, at 410-955-9444 or 1-800-765-5447, and ask for the pediatric oncology attending physician.

Read more about appointments.

Our Childhood Sarcoma Experts


The Musculoskeletal Tumor Program includes a robust translational research program, in which our sarcoma doctors also conduct laboratory research to develop innovative therapies for bone and soft tissue sarcomas and bring them to clinical trials. We also participate in clinical trials run by the Sarcoma Alliance for Research Through Collaboration (SARC), a consortium of sarcoma programs from across North America, and by the Children’s Oncology Group (COG).  In addition, industry-sponsored trials and clinical trials run by the Pediatric Oncology Experimental Therapeutics Investigators’ Consortium (POETIC) ensure that in addition to standard therapies, almost every child treated within the Johns Hopkins Musculoskeletal Tumor Program will have the opportunity to participate in cutting edge clinical research.

One ongoing effort aims to identify stem cells in certain bone tumors, and understanding how these cells elude drug therapies to drive the growth and spread of cancer.

Read more about sarcoma research at Johns Hopkins.

Patient stories

Meet Ben
Ben is a fun-loving 13 year-old who enjoys skateboarding and playing the drums. In January of 2006, Ben was diagnosed with Ewing’s Sarcoma, a rare cancer that is found in bones and soft tissue.  He was 8 years old. Read more.

Meet Carla
Carla was fifteen years old, an active 10th grader who loved music and dancing, when she learned she had cancer.  She was walking down the steps at home when her leg suddenly gave way.  Her mother, Clara, knew something was wrong when her doctor at Wyman Park didn’t even ask for an x-ray.  Instead the family was sent straight to Johns Hopkins Hospital, where they found out Carla had osteosarcoma. Read more.


Johns Hopkins Children's Center

Pediatric Oncology facilities are located in the Johns Hopkins Children's Center.