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Research Cores

Biostatistics, Epidemiology & Data Management (BEAD) Core

The BEAD Core provides consulting and support services to new and established investigators engaged in human subject research on the Bayview campus. Specific services include programming for new and ongoing research projects, basic and complex biostatistical analyses, as well as consultation and support for study design, analysis plans, manuscript preparation, and public presentations.

Seminar Series: Clinical Epidemiology and Biostatistics for the Practitioner

The Bayview Biostatistics, Epidemiology and Data Management (BEAD) Core hosts a series of 1-day workshops (8:30am – 4:00pm) titled Clinical Epidemiology and Biostatistics for the Practitioner. These seminars are provided in an easy-to-understand format geared towards practitioners and cover topics related to epidemiology and biostatistics. The information will be presented in a conversational manner with applicable clinical examples. Participants are also encouraged to bring current projects they might be working on or beginning to conceptualize as there will be time devoted to smaller break-out sessions with BEAD Core members available for short consults. This series will be sponsored by the BEAD Core and thus will be at no cost to research-oriented practitioners of the Johns Hopkins Bayview campus.

Clinical Epidemiology and Biostatistics for the Practitioner seminar: 2012-2013 dates and Registration form.For more information contact the director, Sharon R. Ghazarian, PhD at 410-550-4146 or e-mail sghazarian@jhmi.edu.

Brain Imaging Core

The focus of the Johns Hopkins Bayview Brain Imaging Core is to facilitate the integration of neuroimaging methods into clinical translational research. The core will provide scientific and technical expertise in neuroimaging protocol development, image processing and analysis.

For more information contact Gwenn Smith, Ph.D. at 410-550-8696 or e-mail gsmith95@jhmi.edu.

Center for Inherited Disease Research (CIDR)

www.cidr.jhmi.edu

The Johns Hopkins University CIDR/SNP Center, located in the Triad building, is a high throughput genotyping facility serving JHU and the scientific community at large.  It is part of The Genetic Resources Core Facility (GRCF), a JHU service center with six divisions. Collectively, these divisions offer a number of products and services to aid researchers in molecular biology and genetics studies. It is our mission to provide solutions to the everyday challenges of laboratory research. Additionally, the GRCF sponsors various educational programs, product seminars and an annual symposium.

For more information please call 410-550-7042 or e-mail info@cidr.jhmi.edu.

Core Store

www.jhucorestore.com

The JHU Core Store provides one-stop shopping for more than 100,000 products from 16 of the leading life science suppliers with no shipping, handling or ice fees.  There is also convenient 24/7 access to the top selling products on the 1st floor of the Asthma & Allergy Building.

For more information please contact Lee Hilliard at 410-502-3959 or e-mail lhillia1@jhmi.edu.

Flow Cytometry Core

www.hopkinsmedicine.org/flowcytometry/bayview

The Johns Hopkins Bayview Flow Cytometry Shared Resource Center exists to support the research initiatives of Johns Hopkins Bayview Faculty and staff. We are committed to providing state-of-the art flow cytometry technology to address cutting edge questions in biomedical research.  It is located in the Mason F. Lord Building, Center Tower, Room 5-548.

For more information contact the director, Mark Soloski, Ph.D., at 410-550-8493 or email msolosk1@jhmi.edu. You may also contact the Flow Cytometry Lab Manager, Joe Chrest, at 410-550-8291 or email jchrest@jhmi.edu.

Genomics/Genetics Core

grcf.med.jhu.edu

The Lowe Family contributions created the Genomics Center at Johns Hopkins Bayview, directed by Kathleen Barnes, Ph.D.  Genomics is the study of which genes are turned on or off during certain diseases.  Philanthropic funding made possible the recruitment of Dr. Felipe Andrade, a basic scientist in genomics.  Drs. Barnes, Andrade and their team are working to identify the genes that contribute to flares and remissions of vasculitis, rheumatoid arthritis, systemic lupus and other chronic inflammatory diseases.

The Genetic Resources Core Facility is a JHU service center including the Core Store and five Research Services.  Collectively, these divisions offer a wide variety of products and services to all Hopkins researchers. The divisions of the GRCF include:

Institute for Clinical and Translational Research (ITCR)

ictr.johnshopkins.edu
jhbgcrc.jhu.edu/Resources.cfm

The Clinical and Translational Science Award (CTSA) from the NIH is a resource grant that supports the Johns Hopkins ICTR. This includes the Clinical Research Unit (CRU) on the Bayview Campus.  The Bayview CRU, located on the 3rd floor of the B building, provides clinical research infrastructure resources including dedicated research nursing and specimen processing, a Sleep Research Core, Cardiovascular Imaging Core, Body composition and Exercise Core, Nutrition research support, and a Core laboratory. Support for informatics and biostatistics is also available through the ICTR.

For more information contact Debra Grudzien, CRU administrative manager, at 410-550-1880 or e-mail dgrudzi1@jhmi.edu.

Microscopy/Confocal Imaging Core

The Microscopy Core at the Johns Hopkins Bayview offers confocal laser scanning microscopy services to the Hopkins community and beyond. Located in the Johns Hopkins Asthma & Allergy Center (2A.28), the Microscopy Core is available to help researchers develop technical solutions for special research needs. The Leica TCS SP5 confocal microscope is one of the top systems in the field, equipped with eight laser lines, four objective lenses and six PMT detectors. It's capable of simultaneous detection of up to five fluorescence channels. In addition to typical confocal applications, such as collecting digital fluorescence z-stacks at improved resolution, more advanced applications such as FRET and FRAP also are available.

For more information about the Microscopy Core at Johns Hopkins Bayview, contact Ramana Sidhaye, M.D. at vsidhay1@jhmi.edu.

Multiphoton Microscopy Core

The Multiphoton Microscopy Core Facility of NIH/NIDA at Johns Hopkins Bayview provides multiphoton confocal microscopy, optical stereology microscopy and image analysis services to the NIH/NIDA community and beyond by updating researchers of advanced light microscopy and image analysis techniques, training users on optimal operation of the instruments and image analysis software, and providing consultations for optimal design of advanced light microscopy experiments. This Facility has a Zeiss LSM 710 NLO Multiphoton Confocal Microscope, a Zeiss ApoTome Super-Resolution Microscope, and a PE UltraView Spinning Disk Confocal Microscope (INBS).   The image analysis software packages include MBF Stereo Investigator, MBF Neurolucida, Zeiss ZEN 2009, PE Volocity (INSB) and MD MetaMorph (INSB).

For more information please contact Gary Li, PhD at gary.li@nih.gov.

Proteomics Research Center

proteomics.jhu.edu

The Courtney Amos Research Fund and the Daniel P. Amos Family Proteomics Center were established to study and apply proteomics using state-of-the-art technologies to understand clinical questions.  Proteomics, the analysis of proteins encoded by genes and which can be modified to change function, permits physicians and scientists to understand and intervene in various forms of inflammation that underlie many diseases. Jenny Van Eyk, Ph.D., a leader in proteomics research, joined the Johns Hopkins faculty to lead the Proteomics Research Center.

For more information about the Proteomics Core at Johns Hopkins Bayview, contact Jenny Van Eyk, Ph.D., at 410-550-8511 or e-mail Jvaneyk1@jhmi.edu.

Rheumatic Disease Research Core Center (RDRCC)

The Rheumatic Disease Research Core Center (RDRCC) includes a free-standing bioassay service which affords clinical and basic science researchers the ability to investigate novel questions that could not otherwise be addressed, due to a lack of time, expertise or infrastructure.  Current bioassay services include processing of whole blood (RNA/DNA isolation, PBMC preparation or serum separation), immunostaining of human or animal tissues, and immunoassays including ELISA and immunoprecipitation.  The core also offers sample storage and/or shipping services.  Sample barcoding and data management services are currently being developed.

To learn more about the bioassay core and its services, contact Laura Gutierrez, MD at lgutier3@jhmi.edu or 410-550-1468.

SciVal Experts

http://www.experts.scival.com/jhu/

SciVal Experts (previously named Collexis) is an expertise portal and a key component of Johns Hopkins University's mission to catalyze the application of new knowledge and techniques to clinical practice at the front lines of patient care.  SciVal Experts is a subscription tool supported by the Welch and Harrison Libraries for internal and public users to identify Johns Hopkins faculty biomedical experts and their publications by area of expertise, based on published output indexed in the PubMed biomedical literature citation database. The SciVal Experts resource facilitates faculty research and project collaboration. SciVal Experts can be accessed at or through the Welch or Harrison Library websites which also offer tutorials on optimizing use of the site.

 
 
 
 

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