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Research Cores

Brain Imaging Core

The focus of the Johns Hopkins Bayview Brain Imaging Core is to facilitate the integration of neuroimaging methods into clinical translational research. The core will provide scientific and technical expertise in neuroimaging protocol development, image processing and analysis.

For more information, contact Gwenn Smith, Ph.D. at 410-550-8696 or e-mail gsmith95@jhmi.edu.

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Center for Behavior and Health (CBH)

The Johns Hopkins Center for Behavior and Health (CBH) is located on the Johns Hopkins Bayview Medical Center campus. The mission of the CBH is to discover new insights into how behavior influences health and translate this knowledge into novel clinical and educational programs that prevent and improve the treatment of chronic diseases. The Center is a think tank of over 40 interdisciplinary experts from multiple schools within Johns Hopkins, including: medicine, nursing, and public health. The core faculty meet monthly to guide three signature initiatives. These initiatives include:

  1. The Behavioral Medicine Discovery Program to foster novel interdisciplinary research.
  2. The Behavioral Medicine on the Wards Program to educate and empower physicians and healthcare professionals in addressing healthy behavior change; and
  3. The B-TEAM, a grass roots, disruptive behavioral hit team that targets and improves deficiencies in healthcare system processes and patient care practices to promote healthy behavior.

For more information, visit hopkinsmedicine.org/behaviorandhealth, or contact Michelle Polley at 410-550-7000 or mpolley1@jhmi.edu.

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Center for Child and Community Health Research (CCHR)

The Center for Child and Community Health Research (CCHR) is dedicated to improving the lives and communities of children, adolescents and young adults by engaging in high-quality, translational public health research according to the highest scientific and ethical standards. CCHR was established in 1998 and moved to the Johns Hopkins Bayview campus in 2006. The current director is Jacky Jennings, M.D.; the previous Director was Jonathan Ellen, M.D..

Funding for CCHR is from sponsored and non-sponsored sources including the NIH, CDC, RWJF, local foundations and contracts for evaluation from health departments nation-wide. We provide many forums for scientific dialogue including a Research In Progress Rounds and Internal Scientific Review Committees.

For more information, visit www.jhcchr.org.

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CCHR Biostatistics, Epidemiology & Data Management (BEAD) Core

The BEAD Core provides research support services to new and established faculty investigators on the Johns Hopkins Bayview campus. Johns Hopkins Bayview faculty receive free (up to 20 hours) services through the generous support of the vice dean David Hellmann, M.D. The Core also accepts direct fee-for-service work. Core services include:

  • epidemiologic study design support
  • biostatistical analyses
  • database development and maintenance
  • statistical analytic plans for grant submissions
  • power and sample size calculations

For more information or to set up an appointment, contact cchrbead@jhmi.edu or visit jhcchr.org/bead.

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Center for Inherited Disease Research (CIDR)

The Center for Inherited Disease Research (CIDR) is a valuable national resource for cutting-edge genetic research, established in 1996. CIDR provides high quality next generation sequencing and genotyping services to investigators working to discover genes that contribute to disease. On-site statistical geneticists provide valuable insight into analysis issues as they relate to study design, data production and quality control. In addition, CIDR has a consulting agreement with the University of Washington Genetics Coordinating Center (GCC) to provide statistical and analytical support, most predominantly in the areas of GWAS data cleaning and methods development.

The CIDR contract is funded by 13 NIH Institutes and provides genotyping, sequencing and statistical genetic services to investigators approved for access through competitive peer review. An application is required for projects supported by the NIH CIDR Program.

For more information, please contact Kim Doheny at kdoheny@jhmi.edu or visit www.cidr.jhmi.edu.

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Centro SOL

The Center for Salud/Health and Opportunity for Latinos aims to promote equity in health and opportunity for Latinos by advancing clinical care, research, education and advocacy at Johns Hopkins and beyond in active partnership with local organizations. Each component is integrated by faculty, staff and students from Hopkins and community leaders.

Centro SOL offers research support services to Johns Hopkins research teams that want to engage Latino populations in research. Services include tailoring study design and recruitment to the local Latino population, translation of study documents, IRB application preparation related to the inclusion of limited English proficiency populations and assessments of linguistic and cultural suitability of study materials. Research services faculty and staff are also available to play a larger role and collaborate on projects and funding applications where appropriate.

For more information on engaging Centro SOL Research support services, pricing, policies or to schedule an initial consult, please visit http://bit.ly/CSresearch-services or email centrosol@jhmi.edu. Find out more about Centro Sol at www.jhcentrosol.org.

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Flow Cytometry Core

The Johns Hopkins Bayview Flow Cytometry Shared Resource Center exists to support the research initiatives of Johns Hopkins Bayview faculty and staff. We are committed to providing state-of-the art flow cytometry technology to address cutting edge questions in biomedical research.  The Resource Center is located in the Mason F. Lord Building, Center Tower, Room 5-548.

For more information, visit hopkinsrheumatology.org/rdrcc/flow-cytometry-core, or contact Mark Soloski, Ph.D., at 410-550-8493 or msolosk1@jhmi.edu. You may also contact flow cytometry lab manager Raffaello Cimbro at 410-550-8291 or rcimbro1@jhmi.edu.

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Genetic Resources Core Facility

The Genetic Resources Core Facility (GRCF)  is a JHU service center which includes the Core Store, Biorepository & Cell Center and DNA Services. Collectively, these groups produce a number of products and services to aid researchers performing studies in molecular biology and genetics. It is our mission to provide high quality, cost-effective research services and products to investigators throughout the Johns Hopkins scientific community.

  • Biorepository & Cell Center
    Facilitates basic scientific research by providing expertise and service in all mammalian cell culture. For more information, visit http://cellcenter.grcf.jhmi.edu.
  • Core Store
    Provides one-stop shopping for more than 150,000 products from 16 of the leading life science companies. In addition to its product offerings, the store charges no shipping and handling fees and has free delivery to three campuses: East Baltimore, Johns Hopkins Bayview and Homewood. There is also convenient 24/7 access to several hundred products via the Core Store 24/7 at Blalock 1026, CRB I B02A ,and the Johns Hopkins Asthma & Allergy Center 1A.C4. For more information, visit jhucorestore.com or contact Lee Hilliard at 410-502-3959 or lhillia1@jhmi.edu.
  • DNA Services
    Works together to provide solutions for all of your DNA and RNA needs. We handle basic needs like DNA isolation, plating and storage, “traditional” core services like Sanger sequencing, PCR support and genotyping, and the more complex needs presented by the constantly changing field of next generation sequencing.

For more information, visit http://grcf.med.jhu.edu or email grcf@jhmi.edu.

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Lowe Family Genomics Core

The Lowe Family contributions created the Genomics Center at Johns Hopkins Bayview, directed by Kathleen Barnes, Ph.D. Genomics is the study of which genes are turned on or off during certain diseases. Philanthropic funding made possible the recruitment of Dr. Felipe Andrade, a basic scientist in genomics. Drs. Barnes, Andrade and their team are working to identify the genes that contribute to flares and remissions of vasculitis, rheumatoid arthritis, systemic lupus and other chronic inflammatory disease,s including acute and chronic lung diseases and allergic disease.

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Histology Core

The Johns Hopkins Bayview Histology Core provides frozen and paraffin embedding and sectioning for basic research investigators in the Johns Hopkins community, including basic brightfield staining (i.e., H&E). It is located in room LA2 of the Johns Hopkins Asthma & Allergy Center.

For more information, contact James E. Watkins III at 410-550-8107 or jwatkins@jhmi.edu.

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Institute for Clinical and Translational Research (ITCR)

The Clinical and Translational Science Award (CTSA) resource granted by the NIH that supports the Johns Hopkins ICTR. The ICTR supports the Clinical Research Unit (CRU) on the Johns Hopkins Bayview campus and the CRUs on the East Baltimore campus.

The Johns Hopkins Bayview CRU (located on the fourth floor of the 301 building) provides clinical research infrastructure resources including dedicated research nursing and specimen processing, a Sleep Research Core, Cardiovascular Imaging Core, Body Composition and Exercise Core, nutrition research support, and a core laboratory. Parking for subjects is available adjacent to the 301 building. Support for informatics and biostatistics is also available through the ICTR.

For more information, contact Debra Grudzien, CRU administrative manager, at 410-550-1880 or dgrudzi1@jhmi.edu. Also visit http://ictr.johnshopkins.edu/client and http://jhbgcrc.jhu.edu/Resources.cfm.

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Microscopy/Confocal Imaging Core

The Microscopy Core at Johns Hopkins Bayview offers confocal laser scanning microscopy services to the Hopkins community and beyond. Located in the Johns Hopkins Asthma & Allergy Center (2A.28), the Microscopy Core is available to help researchers develop technical solutions for special research needs.

The Leica TCS SP5 confocal microscope is one of the top systems in the field, equipped with eight laser lines, four objective lenses and six PMT detectors. It's capable of simultaneous detection of up to five fluorescence channels.

In addition to typical confocal applications, such as collecting digital fluorescence z-stacks at improved resolution, more advanced applications such as FRET and FRAP also are available.

For more information about the Microscopy Core at Johns Hopkins Bayview, contact Ramana Sidhaye, M.D., at vsidhay1@jhmi.edu.

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Older Americans Independence Center (OAIC) Research Cores

The Older Americans Independence Center (OAIC) is an NIH-sponsored research center focused on the study of the causes and consequences of frailty in older adults. The OAIC has three research cores, a training core, and a pilot core that provide resources for a broad range of investigators interested in frailty and aging research.

  • The Biostatistics Core offers analytical and study development and design support, and assistance with gaining access to stored data from population data bases of older adults such as the Women’s Health and Aging Studies I and II.
  • The Molecular Measures Core supports inflammatory, mitochondrial, endocrine and other clinical and molecular based measurements, and provides animal models and stored human serum for eligible investigators.
  • The Clinical Translational Core provides access to a registry of older adults interested in participating in clinical research, and support for eligible investigators for IRB and clinical protocol development.
  • The Research & Career Development Core offers salary and research core support to junior faculty members through an annual RFA process.
  • The Pilot Core offers funding for novel projects related to frailty and aging-related biological vulnerability.

Jeremy Walston, M.D., serves as the primary investigator for OAIC. For more information, visit http://coah.jhu.edu/oaic or contact OAIC administrator Brian Buta at bbuta@jhmi.edu.

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Proteomics Research

The Courtney Amos Research Fund and the Daniel P. Amos Family Proteomics Center was established to study and apply proteomics using state-of-the-art technologies to understand clinical questions. Proteomics, the analysis of proteins encoded by genes and which can be modified to change function, permits physicians and scientists to understand and monitor the underlying molecular mechanisms of many diseases. Allen D. Everett, M.D., a leader in clinical translational proteomics research, leads the Proteomics Research Center which uses a high resolution Orbitrap Elite mass spectrometer.

For more information about the Proteomics Center at Johns Hopkins Bayview, visit http://proteomics.jhu.edu, or contact Allen D. Everett, M.D., at 410-614-0513 or aeveret3@jhmi.edu.

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Rheumatic Disease Research Core Center (RDRCC)

The Rheumatic Disease Research Core Center (RDRCC) includes a free-standing bioassay service which affords clinical and basic science researchers the ability to investigate novel questions that could not otherwise be addressed, due to a lack of time, expertise or infrastructure. Current bioassay services include processing of whole blood (RNA/DNA isolation, PBMC preparation or serum separation), immunostaining of human or animal tissues, and immunoassays including ELISA and immunoprecipitation. The core also offers sample storage and/or shipping services.  Sample barcoding and data management services are currently being developed.

To learn more about the bioassay core and its services, contact Laura Gutierrez, M.D., at 410-550-1468 or lgutier3@jhmi.edu.

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SciVal Experts

SciVal Experts (previously named Collexis) is an expertise portal and a key component of The Johns Hopkins University's mission to catalyze the application of new knowledge and techniques to clinical practice at the front lines of patient care. SciVal Experts is a subscription tool supported by the Welch and Harrison Libraries for internal and public users to identify Johns Hopkins faculty biomedical experts and their publications by area of expertise, based on published output indexed in the PubMed biomedical literature citation database. The SciVal Experts resource facilitates faculty research and project collaboration.

SciVal Experts can be accessed at or through the Welch or Harrison Library websites, which also offer tutorials on optimizing use of the site. For more information, visit www.experts.scival.com/jhu.

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