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Vascular Disease

1. NIH-Sponsored Peripheral Arterial Disease (PAD) Clinical Trial Recruiting Patients at Johns Hopkins Bayview

Peripheral arterial disease (PAD) is a major source of morbidity and mortality, particularly in older individuals. Claudication (leg pain with walking, typically relieved with rest) may be a symptom of PAD.

Claudication: Exercise Versus Endoluminal Revascularization (CLEVER) is a prospective, randomized, multicenter clinical trial designed to determine optimal treatment for claudication due to aortoiliac disease. It compares the benefits of supervised exercise, endovascular revascularization and optimal medical care.

Who may be eligible: Age 40 and older with intermittent claudication due to aortoiliac peripheral arterial disease

If you are interested in learning more about this research study or if you have a patient who may be eligible, please call the Johns Hopkins Center for Vascular Medicine at 410-955-5897.

PI: Elizabeth Ratchford, M.D.

2. Venous Leg Ulcers

Do you have venous stasis disease? Do you have a leg ulcer? Johns Hopkins Wound Center is conducting a research study on venous leg ulcers using an advanced biologic skin repair therapy.

Patients with six-week to two-year-old venous leg ulcers are needed to participate in the study. Participants would come to the wound clinic at Johns Hopkins Bayview on a weekly basis for spray application of study skin cells and free comprehensive wound care, including dressings, pressure wraps and shoes.

Study participants will be compensated $35 per visit. Approximately 15 visits are required.

For more information or to find out in you're eligible to participate, please contact Yolanda Johnson at 410-550-4724.

PI: Gerald Lazarus, M.D.

3. Are you between 8-20 weeks pregnant? Would you like to participate in a research study?

The Johns Hopkins Vein Center is conducting a non-invasive research study to evaluate the effect of compression stocking use in preventing the development of venous insufficiency. Venous insufficiency is a condition in which the veins have problems sending blood from the legs back to the heart. It can cause:

  • Varicose veins
  • Skin changes
  • Leg swelling
  • Pain
  • Non-healing ulcers
  • Thrombophlebitis

To be eligible for this study you must be:

  • Female between 18-45 years of age
  • Between 8-20 weeks pregnant
  • Seeking care for pregnancy at one of these Johns Hopkins locations: Johns Hopkins Bayview, Johns Hopkins Hospital or Johns Hopkins at White Marsh
  • Able to undergo two ultrasound exams on the legs
  • Able to attend three appointments & participate in phone interviews

PI: Jennifer Heller, M.D.

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