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Johns Hopkins Children’s Center

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Lipid Research and Atherosclerosis Center

The Division of Lipid Research and Atherosclerosis at Johns Hopkins Children's Center houses the Johns Hopkins Lipid Clinic, the first in the country to focus on the whole family, is also among the oldest.

Here clinician scholars and researchers develop new and better ways to diagnose and treat lipid disorders in children, adolescents and adults. The clinic also provides a unique opportunity to collect and compare biochemical and genetic data among pediatric and adult family members. The clinic sees 2,000 new and follow-up patients annually; 70% are adults. The lipid clinic and its associated lipid and lipoprotein laboratory rely on philanthropy.

Novel research is focused on high density lipoproteins (HDL), which may protect against heart disease. A new project, the Triad Heart Study collects data from families with and without elevated levels of a large HDL (father, pregnant mother and then infant at birth).  Results to date indicate that the expression of this phenotype is inherited, opening the way to future biochemical and molecular genetic studies that may lead to new and better treatments to prevent CVD.

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