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Neurointerventional Research Center

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The mission of the Johns Hopkins Neurointerventional Research Center (NRC) is to broaden the understanding of diagnostic procedures and treatment options for conditions involving the brain, the head & neck region, and the spine & spinal cord through clinical, translational, and basic science research.

Our team conducts research on a wide variety of interventional neuroradiology topics and publishes results in numerous peer-reviewed publications. Knowledge gained through NRC investigations leads to earlier diagnosis of neurovascular conditions and safer, more effective therapies for patients.

Our areas of research focus include:

  • Cerebral angiography
  • Flat Panel Catheter Angiotomography (FPCA)
  • Intra-arterial chemotherapy
  • Neurovascular anatomy and variations
  • Pseudotumor cerebri
  • Spinal angiography
  • Spine interventions
  • Stroke treatment

Selected Recent Publications

  1. Orru, E., Sorte, D. E., Gregg L., Wolinsky, J. P., Jallo, G. I., Bydon, A., Tamargo, R. J., & Gailloud, P. (2017). Intraoperative spinal digital subtraction angiography: indications, technique, safety, and clinical impact. Journal of neurointerventional surgery, 9(6), 601-607.
  2. Hui, Ferdinand K., Amgad El Mekabaty, Jacky Schultz, Kelvin Hong, Karen Horton, Victor Urrutia, Imama Naqvi, Shawn Brast, John K. Lynch, and Zurab Nadareishvili. "Helistroke: neurointerventionalist helicopter transport for interventional stroke treatment: proof of concept and rationale." Journal of NeuroInterventional Surgery (2017): neurintsurg-2017
  3. Qin, Huamin, Miroslaw Janowski, Monica S. Pearl, Izabela Malysz-Cymborska, Shen Li, Charles G. Eberhart, and Piotr Walczak. "Rabbit Model of Human Gliomas: Implications for Intra-Arterial Drug Delivery." PloS one 12, no. 1 (2017): e0169656.
  4. El Mekabaty, A., Pardo, C. A., & Gailloud, P. (2017). The yield of initial conventional MRI in 115 cases of angiographically confirmed spinal vascular malformations. Journal of neurology, 264(4), 733-739.
  5. Schneider, Tanja, Emily Wyse, and Monica S. Pearl. "Analysis of radiation doses incurred during diagnostic cerebral angiography after the implementation of dose reduction strategies." Journal of neurointerventional surgery 9, no. 4 (2017): 384-388.
  6. Gregg, L., Sorte, D. E., & Gailloud, P. (2017). Intraforaminal Location of Thoracolumbar Radicular Arteries Providing an Anterior Radiculomedullary Artery Using Flat Panel Catheter Angiotomography. American Journal of Neuroradiology, 38(5), 1054-1060.
  7. Hui, Ferdinand K., Nancy A. Obuchowski, Seby John, Gabor Toth, Irene Katzan, Dolora Wisco, Esteban Cheng-Ching, Ken Uchino, Shu-Mei Man, and Shazam Hussain. "ASPECTS discrepancies between CT and MR imaging: analysis and implications for triage protocols in acute ischemic stroke." Journal of neurointerventional surgery 9, no. 3 (2017): 240-243.
  8. Gailloud, P., Gregg, L., Pearl, M. S., & San Millan, D. (2017). Ascending and Descending Thoracic Vertebral Arteries. American Journal of Neuroradiology, 38(2), 327-335.
  9. Brinjikji, Waleed, Arun P. Amar, Josser E. Delgado Almandoz, Orlando Diaz, Pascal Jabbour, Ricardo Hanel, Ferdinand Hui et al. "GEL THE NEC: a prospective registry evaluating the safety, ease of use, and efficacy of the HydroSoft coil as a finishing device." Journal of NeuroInterventional Surgery (2017): neurintsurg-2016.
  10. O'Loughlin, Lauren, Mari L. Groves, Neil R. Miller, and Monica S. Pearl. "Cerebrofacial arteriovenous metameric syndrome (CAMS): a spectrum disorder of craniofacial vascular malformations." Child's nervous system: ChNS: official journal of the International Society for Pediatric Neurosurgery 33, no. 3 (2017): 513-516.