Clinical Trials

For more information, please email Beatriz Kohler regarding clinical trials: inr@jhmi.edu

Intra-arterial Chemotherapy for the Treatment of Intraocular Retinoblastoma

The purpose of this study is to show that delivering chemotherapy directly through the artery supplying the eye (ophthalmic artery) in patients with retinoblastoma is a safe and effective treatment alternative to conventional systemic chemotherapy, external beam radiation, and enucleation (surgical removal of the eye).

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Intra-arterial Chemotherapy for the Treatment of Progressive Diffuse Intrinsic Pontine Gliomas (DIPG)

This study was sponsored by Solving Kids' Cancer

The purpose of this study is to show that delivering chemotherapy directly through the arteries that supply blood to a type of brainstem tumor is a safe and effective treatment alternative to conventional systemic chemotherapy. This study was sponsored by Solving Kids’ Cancer, a non-profit organization. 

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Interventional Management of Stroke, IMS III

The Interventional Management of Stroke (IMS III) Trial is a randomized, open-label multi-center study that will compare a combined intravenous (IV) and intra-arterial (IA) treatment approach to restoring blood flow to the brain to the current standard FDA approved treatment approach of giving IV rt-PA alteplase, Activase,® alone.

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