One key to the success of any future cell-based therapy—successfully transplant and maintain cells in a patient—will require a better understanding of how the immune system develops and functions. Researchers in our Immunobiology program at ICE are keen to unravel the molecular mechanisms behind the human immune system as well as how stem cells differentiate into specialized immune cells. Using a combination of molecular, cellular and genomic biology techniques as well as mouse models, the Immunobiology labs strive to unravel the mysteries of how the immune system distinguishes between self and non-self and how that might be harnessed to improve transplantation therapies and treatments.
Faculty
Stephen Desiderio, M.D., Ph.D., Director
Abraham “Avi” Kupfer, Ph.D., co-Director
Mathias Oelke, Ph.D.
Joel Pomerantz, Ph.D.
Jonathan Schneck, M.D., Ph.D.


