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Lab-Grown Nerve Cells Make Heart Cells Throb
Researchers report that a type of lab-grown human nerve cells can partner with heart muscle cells to stimulate contractions. Because the heart-thumping nerve cells were derived from induced pluripotent stem cells, the researchers believe the cells will be an aid in studying disorders that affect the nervous system.
Cells Engineered from Muscular Dystrophy Patients Offer Clues to Symptoms
Researchers report they have inadvertently found a way to make human muscle cells bearing genetic mutations from people with Duchenne muscular dystrophy. The research should shed light on how subtle genetic differences among DMD patients produce symptoms with a wide range of severity and disability.
Sophisticated ‘Mini-Brains’ Add to Evidence of Zika’s Toll on Fetal Cortex
Studying a new type of pinhead-size, lab-grown brain made with technology first suggested by three high school students, researchers have confirmed a key way in which Zika virus causes microcephaly and other damage in fetal brains: by infecting specialized stem cells that build its outer layer, the cortex.
How Cancer Stem Cells Thrive When Oxygen Is Scarce
Working with human breast cancer cells and mice, new experiments suggest how certain cancer stem cells thrive in low oxygen conditions. Proliferation of such cells, which tend to resist chemotherapy and help tumors spread, are considered a major roadblock to successful cancer treatment.
Jeff Bulte's Paper Among the Most Cited in Nature Biotechnology
To celebrate their 20th anniversary, Nature Biotechnology published a list of their top cited papers and one of Jeff Bulte's came in at #11 with nearly 52 citations per year since it was published in 2001. The paper revealed a new way to track stem cells implanted in research animals using magnetic nanoparticles.
Podcasts with ICE researchers
- Finding a Cure for Parkinson's Disease with Ted Dawson
- Scientists Convert Blood Cells Back to Embryonic Stem Cell-Like State with Elias Zambidis
- Transforming Skin Cells to Stem Cells with Ted Dawson
- What Anti-Depression Treatments Actually Target in the Brain with Hongjun Song
- Preventing Breast Cancer Spread with Gregg Semenza
- How the Zika Virus May Cause Microcephaly with Hongjun Song
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Stem cell research at Johns Hopkins Medicine
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