Piotr Walczak, M.D., Ph.D.
The Walczak lab develops cell-based therapies for the treatment of neurological disorders by using myelinating glial progenitor cells. These cells are capable of replenishing dysfunctional or lost myelin in disorders like multiple sclerosis, congenital dysmyelination and stroke.
Primary glial progenitors derived from human fetal tissue show great therapeutic potential in dysmyelinated mice because of their extensive myelination and extended survival. However, Walczak’s team is investigating the use of induced pluripotent stem cells instead as a more plentiful source of glial progenitors. By developing new strategies for efficient intravascular, MRI-guided delivery of progenitor cells to brain lesions and applying non-invasive imaging technology to monitor survival and functional integration of the transplanted cells, the research group hopes to develop successful therapeutics for demyelinating diseases.
Associate Professor of Radiology
View a list of publications on PubMed.