Founded in 2001, the mission of the Institute for Cell Engineering at the Johns Hopkins School of Medicine is to foster a multidisciplinary environment in which experts from across the Johns Hopkins University collaborate to understand the biology of stem cells, basic cell processes, and how to apply new ideas to further the field of cell engineering. ICE supports and encourages the application and development of new cell technologies to ultimately develop cell-based therapies to treat human disease.
Our four basic research programs, Immunobiology, Neuroregeneration, Stem Cell Biology and Vascular Biology, focus on a wide range of conditions including Parkinson’s disease, ALS, diabetes, heart failure, cancer, stroke and spinal cord injury.
Researchers in the Immunobiology program have made many advances in understanding how immune cells function during immune response in hopes of developing therapies that treat immune system deficiencies, autoimmunity and cancer.
In the Neuroregeneration program, the focus is on comprehending how nerve cells develop and function and identifying and characterizing the molecules that protect against stresses that cause cell death.
Scientists in the Stem Cell Biology program have improved the methods for coaxing stem cells into desired cell types for both further study and potential therapies. The team is heavily focused on developing induced pluripotent stem cells from adult tissues to improve current technologies to bring cell therapies to clinical care.
In the Vascular Biology program, researchers have made considerable progress in understanding how blood vessels form with the goal of developing new clinical treatments for stroke and cancer.