Heng Zhu, Ph.D.

Additional Information

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Key Publications

HOT PAPER! Lin Y-Y, Lu J-Y, Zhang J, Walter W, Dang W, Wan J, Tao S-C, Qian J, Zhao Y, Boeke JD, Berger SL, Zhu H. (2009). Protein acetylation microarray reveals NuA4 controls key metabolic target regulating gluconeogenesis. Cell. 136, 1073-1084. PubMed Link

Chen C-S, Korobkova E, Chen H, Zhu J, Jian X, Tao S-C, He H and Zhu H. (2008). A proteome chip approach reveals new DNA damage recognition activities in Escherichia coli. Nature Methods. 5, 69-74. PubMed Link

Evans-Nguyen KM, Tao SC, Zhu H and Cotter RJ. (2008). Protein arrays on patterned porous gold substrates interrogated with mass spectrometry: detection of peptides in plasma. Anal Chem. 80, 1448-1458. PubMed Link

Lu J-Y, Lin Y-Y, Tao S-C, Zhu J, Pickart CM, Qian J and Zhu H. (2008). Functional dissection of a HECT ubiquitin E3 ligase. Mol Cell Proteomics. 7, 35-45. PubMed Link

Tao SC, Li Y, Zhou J, Qian J, Schnaar RL, Zhang Y, Goldstein IJ, Zhu H and Schneck JP. (2008). Lectin microarrays identify cell-specific and functionally significant cell surface glycan markers. Glycobiology. Jul 17. [Epub ahead of print]. PubMed Link

Hu S, Li Y, Liu G, Song Q, Wang L, Han Y, Zhang Y, Song Y, Yao X, Tao Y, Zeng H, Wang J, Zhu H, Chen Z-N and Wu L. (2007). A protein chip approach for high-throughput antigen identification and characterization. Proteomics. 7, 2151-61. PubMed Link

Tao SC, Chen CS and Zhu H. (2007). Applications of protein microarray technology. Comb Chem High Throughput Screen. 10, 706-718. PubMed Link

Zhu J, Gopinath K, Murali A, Yi G, Hayward SD, Zhu H and Kao C. (2007). RNA-binding proteins that inhibit RNA virus infection. Proc Natl Acad Sci U S A. 104, 3129-3134. PubMed Link

Tao S-C and Zhu H. (2006). Protein chip fabrication by capture of nascent polypeptides. Nature Biotechnology. 24, 1253-1254. PubMed Link

Zhu H, Hu S, Jona G, Zhu X, Kreiswirth N, Willey BM, Mazzulli T, Liu G, Song Q, Chen P, Cameron M, Tyler A, Wang J, Wen J, Chen W, Compton S and Snyder M. (2006). Severe acute respiratory syndrome diagnostics using a coronavirus protein microarray. Proc Natl Acad Sci U S A. 103, 4011-4016. PubMed Link

Chen CS and Zhu H. (2006). Protein microarrays. Biotechniques. 40, 423-429. NO PMID.

Ptacek J, Devgan G, Michaud G, Zhu H, Zhu X, et al. (2005). Global analysis of protein phosphorylation in yeast. Nature. 438, 679-684. PubMed Link

Huang J, Zhu H, Haggarty SJ, Spring DR, Hwang H, Jin F, Snyder M, Schreiber SL. (2004). Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips. Proc Natl Acad Sci U S A. 101, 16594-16599. PubMed Link

Hall DA, Zhu H, Zhu X, Royce T, Gerstein M, Snyder M. (2004). Regulation of gene expression by a metabolic enzyme. Science. 306, 482-484. PubMed Link

Kafadar KA, Zhu H, Snyder M, Cyert MS. (2003). Negative regulation of calcineurin signaling by Hrr25p, a yeast homolog of casein kinase I. Genes Dev. 17, 2698-2708. PubMed Link

Zhu H, Bilgin M, Bangham R, Hall D, Casamayor A, Bertone P, Lan N, Jansen R, Bidlingmaier S, Houfek T, Mitchell T, Miller P, Dean RA, Gerstein M, Snyder M. (2001). Global analysis of protein activities using proteome chips. Science. 293, 2101-2105. PubMed Link

Zhu H, Klemic JF, Chang S, Bertone P, Casamayor A, Klemic KG, Smith D, Gerstein M, Reed MA, Snyder M. (2000). Analysis of yeast protein kinases using protein chips. Nat. Genet. 26, 283-289. PubMed Link