Robert J. Cotter, Ph.D.

Additional Information

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Key Publications

HOT PAPER! Evans-Nguyen KM, Tao SC, Zhu H, Cotter RJ. (2008). Protein arrays on patterned porous gold substrates interrogated with mass spectrometry: detection of peptides in plasma. Anal Chem. 80, 1448-1458. PubMed Link

Scroggins BT, Robzyk K, Wang D, Marcu MG, Tsutsumi S, Beebe K, Cotter RJ, Felts S, Toft D, Karnitz L, Rosen N, Neckers L. (2007). An acetylation site in the middle domain of Hsp90 regulates chaperone function. Molecular Cell. 25, 151-159. PubMed Link

Cotter RJ, Griffith W, Jelinek C. (2007). Tandem time-of-flight (TOF/TOF) mass spectrometry and the curved-field reflectron. J Chromatogr B Analyt Technol Biomed Life Sci. 855, 2-13. PubMed Link

Mathivanan S, Ahmed M, Ahn NG, Alexandre H, Amanchy R, Andrews PC, Bader JS, Balgley BM, Bantscheff M, Bennett KL, Björling E, Blagoev B, Bose R, Brahmachari SK, Burlingame AS, Bustelo XR, Cagney G, Cantin GT, Cardasis HL, Celis JE, Chaerkady R, Chu F, Cole PA, Costello CE, Cotter RJ, et al. (2008). Human Proteinpedia enables sharing of human protein data. Nature Biotechnology. 26, 164-167. PubMed Link

Celic I, Masumoto H, Griffith WP, Meluh P, Cotter RJ, Boeke JD, Verreault A. (2006). The sirtuins Hst3 and Hst4p preserve genome integrity by controlling histone H3 lysine 56 deacetylation. Current Biology. 16, 1280-1289. PubMed Link

Wang D, Kalume D, Pickart C, Pandey A, Cotter RJ. (2006). Identification of protein ubiquitylation by electrospray ionization tandem mass spectrometric analysis of sulfonated tryptic peptides. Analytical Chemistry. 78, 3681-3687. PubMed Link

Wang D, Cole PA, Cotter RJ. (2006). Laser-induced dissociation of phosphorylated peptides using matrix-assisted laser desorption/ionization tandem time-of-flight mass spectrometry. Clinical Proteomics. 2, 133-144.

Hyland EM, Cosgrove MS, Molina H, Wang D, Pandey A, Cotter R, Boeke JD. (2005). Insights into the Role of Histone H3 and Histone H4 Core Modifiable Residues in Saccharomyces cerevisiae. Mol. Cell. Biol. 25, 10060-10070. PubMed Link

Wang D, Cotter RJ. (2005). Approach for Determining Protein Ubiquitination Sites by MALDI-TOF Mass Spectrometry. Anal. Chem. 77, 1458-1466. PubMed Link

Wang D, Xu W, McGrath SC, Patterson C, Neckers L, Cotter RJ. (2005). Direct identification of ubiquitination sites on ubiquitin-conjugated CHIP using MALDI mass spectrometry. J Proteome Res. 4, 1554-1560. PubMed Link

Wang D, Thompson P, Cole PA, Cotter RJ. (2005). Structural Analysis of a Highly Acetylated Protein Using a Curved-Field Reflectron Mass Spectrometer. Proteomics. 5, 2288-2296. PubMed Link

Wang D, Kalb SR, Cotter RJ. (2004). Improved Procedures for N-Terminal Sulfonation of Peptides for Matrix-Assisted Laser Desorption/Ionization Post-Source Decay Peptide Sequencing. Rapid Commun. Mass Spectrom. 18, 96-102. PubMed Link

Wang D, Xu W, Neckers L, Cotter, RJ. (2004). A Novel Strategy for Determining Protein Ubiquitination by Mass Spectrometry. Mol. Cell. Proteomics. 10, S142.

Cotter RJ, Iltchenko S, Wang D. (2004). The Curved-Field Reflectron: PSD and CID without Scanning, Stepping or Lifting. Int. J. Mass Spectrom. 240, 169-182.

Thompson P, Wang D. Wang L, Fulco M, Pediconi N, Zhang D, An W, Ge Q, Roeder RG, Wong J, Levrero M, Sartorelli V, Cotter RJ, Cole PA. (2004). Regulation of the p300 HAT Domain via a Novel Activation Loop. Nat Struct Mol Biol. 11, 308-315. PubMed Link