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Noninvasive Ultrasound Pulses Used to Precisely Tweak Rat Brain Activity
Researchers developed a noninvasive way to release and deliver concentrated amounts of a drug to the brain of rats in a temporary, localized manner using ultrasound. Because these new method can be applied to many other drugs, this new method has the potential to advance many therapies and studies inside and outside the brain.

cilia

Some Cells Need a ‘Haircut’ Before Duplicating
Researchers say this finding is key to better understanding how cells decide to undergo mitosis, the maintenance of tissues and the formation of cancer. They also hope their work will shed light on cilia-related diseases, like polycystic kidney disease, and certain forms of intellectual disability.

fever chart

Here’s Why You Don’t Feel Jet-Lagged When You Run a Fever
A clump of just a few thousand brain cells, no bigger than a mustard seed, controls the daily ebb and flow of most bodily processes in mammals — sleep/wake cycles, most notably. Now, scientists report direct evidence in mice for how those cell clusters control sleep and relay light cues about night and day throughout the body.

immunoresponse

Dual Strategy Teaches Mouse Immune Cells to Overcome Cancer’s Evasive Techniques
By combining two treatment strategies, researchers report they lengthened the lives of mice with skin cancer more than by using either strategy on its own. The combination technique is easily tailored to different types of cancer and have the potential to enhance treatment options for a wide variety of cancer patients.

cells1

Search On For Drug to Tame ‘Hyperactive’ Zinc Transporter and Lower Type 2 Diabetes Risk
Study suggests that a common variant that increases type 2 diabetes risk makes a protein that is more efficient than its less risky counterpart. The “hyperactive” variant, has clarified a long-standing question about the workings of the protein the gene makes. The results may help in identifying drugs that would slow the protein down and perhaps lower diabetes risk for millions.

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