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Diagram of stem cells in fruit fly testis

Surprise: Lost Stem Cells Naturally Replaced By Non-Stem Cells, Fly Research Suggests
Researchers have discovered an unexpected phenomenon in fruit fly testis: When a certain kind of stem cell is killed off experimentally, another group of non-stem cells can come out of retirement to replace them.
      

Graduate student Ali Uneri demonstrates the new surgical guidance system.

New Guidance System Could Improve Minimally Invasive Surgery
Johns Hopkins researchers have devised a computerized process that could make minimally invasive surgery more accurate and streamlined using equipment already common in the operating room.
   

image of a neuron

Brain Degeneration In Huntington’s Disease Caused By Amino Acid Deficiency
Working with genetically engineered mice, neuroscientists report they have identified what they believe is the cause of the vast disintegration of a part of the brain called the corpus striatum in rodents and people with Huntington’s disease: loss of the ability to make the amino acid cysteine.
    

Image overlays of migrating Dictyostelium cells

Cellular 'Counting' of Rhythmic Signals Synchronizes Changes in Cell Fate
Johns Hopkins biologists have discovered that when biological signals hit cells in rhythmic waves, the magnitude of the cells' response can depend on the number of signaling cycles — not their strength or duration.
  

schematic of methylation on DNA

New Tool Pinpoints Genetic Sources Of Disease
Many diseases have their origins in either the genome or in reversible chemical changes to DNA known as the epigenome. Now, results of a new study from Johns Hopkins scientists show a connection between these two “maps.”
      

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