Latest News
Going Places: Rat Brain 'GPS' Maps Routes to Rewards
While studying rats’ ability to navigate familiar territory, Johns Hopkins scientists found that one particular brain structure uses remembered spatial information to imagine routes the rats then follow.
A Protein's Well-Known Cousin Sheds Light on Its Gout-Linked Relative
Scientists have found out how a gout-linked genetic mutation contributes to the disease: by causing a breakdown in a cellular pump that clears an acidic waste product from the bloodstream.
Fatheads: How Neurons Protect Themselves Against Excess Fat
Our brain cells are packed with fat molecules and if the brain cells’ fat content gets too high, they’ll be in trouble. In a recent study in mice, researchers pinpointed an enzyme that keeps neurons’ fat levels under control, and may be implicated in human neurological diseases.
Johns Hopkins Researcher Wins Ho-Am Prize In Medicine
On April 3, South Korea’s Ho-Am Foundation announced that Se-Jin Lee has won this year’s Ho-Am Prize in Medicine. It is awarded each year to an ethnic Korean, and is sometimes referred to as “Korea’s Nobel.”
Science News
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News By Topic
Addiction (back to top)
Aging (back to top)
- Tissue Engineers Report Knee Cartilage Repair Success With New Biomaterial
- Nanoscale Scaffolds and Stem Cells Show Promise in Cartilage Repair
- Hopkins Scientists Turn on Fountain of Youth in Yeast
- Starve a yeast, sweeten its lifespan
- A tiny molecule that might help extend lifespan
- Cancer drug might also treat progeria
- A link between diet and aging?
- Our genome changes as we age
- A Comeback for the Ages: Lamin's connection with aging has reinvigorated research
Anatomy and Evolution (back to top)
Cancer: Potential treatments (back to top)
- HIV And Breast Cancer May Share A Common Enemy: Nelfinavir
- Personalizing Medicine Through Processors and Petabytes
- New Study Helps Predict Which Lung Cancer Drugs are Most Likely to Work
- Just Add Water and...Treat Brain Cancer
- Johns Hopkins Scientists Expose Cancer Cells' Universal 'Dark Matter'
- Solving A Traditional Chinese Medicine Mystery
- Antibiotic Slows Growth of Bladder, Breast Cancer Cells
- New Therapeutic Target for Some Breast Cancers
- More of a reason to eat those vegetables
- A caution about chemicals that alter the epigenome
- Killing cancer cells with a sea sponge?
- Cancer drug might also treat progeria
- Discovery of anticancer proteins
- Preventing sun damage with broccoli sprout extract
- Epigenetics and cancer: blocking the spread
- Stopping cancer by blocking telomerase
- Cancer and toenail fungus?
- 1930s Drug Slows Tumor Growth
Cancer: Learning more about the disease (back to top)
- Pancreatic cancer biomarkers
- Breast Cancer Cells Enticed To Spread By "Tumorous Environment" As Well As Genetic Changes
- You Can't Keep A Good Cell Down
- Rearranging the Cell's Skeleton
- Johns Hopkins Researchers Discover How Some Breast Cancers Alter Their Sensitivity To Estrogen
- Johns Hopkins Scientists Tie Cell Cycle “Clock” To Childhood Cancers
- The Biological Art of Organ Sculpture
- How Does A Heart Know When It's Big Enough
- Computer Predicts Cancer
- Researchers Link Protein to Tumor Growth
- Metastasis: Learning more about how cancer cells spread
- Common epigenetic problem doubles cancer risk
- Linking heart disease and cancer
- Uncontrolled cell growth
- When good cells turn bad: Are stem cells a breeding ground for cancer?
- The hunt for the cell's compass
- Goal: A blood test for colon cancer
- Epigenetics and cancer: Are stem cells the link?
- Shedding light on how lymphomas develop
- A global view of cell movement and metastasis
- Turning off tumor suppressors with RNA
- Down Syndrome may lead to lower risk of colon cancer
- Discovering a controller of cell movement
- Proteins that stop blood vessel growth
- Now Playing: Cell Migration Live!
- Fly Cells Flock Together, Follow The Light
- Controlling tissue and organ growth
- Johns Hopkins Scientists Pull Protein's Tail To Curtail Cancer
Cardiovascular Disease (back to top)
- Mapping the Heart
- Blood Vessels 'Sniff' Gut Microbes To Regulate Blood Pressure
- New Drug Shows Promise for Long QT Syndrome
- Discovery of ‘Master Molecule’ Could Improve Stem Cell Treatment for Heart Attacks
- Linking heart disease and cancer
- Proteins that stop blood vessel growth
- Regulating blood pressure--with gas?
- Cholesterol and drug metabolism
- Chemical found in medical devices impairs heart function
- Clues About Controlling Cholesterol Rise From Yeast Studies
Cystic Fibrosis (back to top)
- A Protein's Well-Known Cousin Sheds Light on Its Gout-Linked Relative
- Swimming the channel
- Defining What Causes the ‘Disease of Kings’
Diabetes and Obesity (back to top)
- Clues Point to Cause of a Rare Fat-Distribution Disease
- Weight Struggles? Blame New Neurons in Your Hypothalamus
- Johns Hopkins Scientists Find Genes Related to Body Mass
- Researchers uncover potential inroad to diabetes treatment
- New compound controls weight and blood sugar in mice
- Future diabetes treatments?
- Lowering blood sugar
- A sweet way to detect prediabetes
- Johns Hopkins Researchers Detect Sweet Cacophany While Listening to Cellular Cross-Talk
- Sweet! Sugar Plays Key Role In Cell Division
Education: Graduate and medical (back to top)
- A new model for graduate biomedical science
- A Reality Check on the Biomedical Job Market
- Techno Love-Hate
- Summer Interns Experience a Taste of Research at Johns Hopkins
- Running in place: Graduate student and postdoc face anxiety as their stints lengthen
- Diversity, by intention
- Of stipends and science
- Good bye and good luck
- New medical school curriculum integrates science and medicine as never before
- Reaching Out
- New Challenges to Classic Dreams
- High school scientists
Employment (back to top)
- The "What" About Bob
- Middle-Author Publications: Do They Matter for Promotion?
- Scientists of the World
- International Opportunities for Life Scientists
- A Reality Check on the Biomedical Job Market
- Hopkins Hosts Visiting Chinese Scientists
- Pleasure's Paths
- Teacher Training for Those Who Can
- Scientists Who Write, Writers Who Do Science
- Peering more closely at peer review
- Scientific integrity in the age of Photoshop
- Retiring Biological Chemistry Professors Honored at Symposium
- Creative solutions to recruit and retain dual-career couples
- Journal fever and the pressure to publish
- Stemming shady science
- Opening the doors of the ivory tower
- Repairing the faculty pipeline
- Luring prospective faculty
- Mr. (or Ms.) PhD Goes to Washington
Epigenetics: Inheritance beyond the genome (back to top)
- How Bees Decide What To Be
- Johns Hopkins Scientists Find Genes Related to Body Mass
- Certain Genes Boost Chances For Distributing A Wide Variety of Random Traits and Drive Evolution
- Johns Hopkins Scientists Expose Cancer Cells' Universal 'Dark Matter'
- Scientists Map Epigenetic Changes During Blood Cell Differentiation
- "Epigenetic" Marks a Clue to Multiple Functions of the Brain
- The Epigenetics Center at Johns Hopkins
- Epigenetics may play a role in common diseases
- A caution about chemicals that alter the epigenome
- Epigenetics' new findings on gene regulation spark new studies
- Common epigenetic problem doubles cancer risk
- Epigenetics and cancer: Blocking the spread
- Epigenetics and cancer: Are stem cells the link?
- Our genomes change as we age
- Deciphering an elephant
- Gene Switch Sites Found Mainly On "Shores," Not Just "Islands" Of The Human Genome
- Large DNA Stretches, Not Single Genes, Shut Off as Cells Mature
Funding Education (back to top)
Funding Scientific Discovery (back to top)
- Hopkins Grad Students and Postdocs Attend Rally for Medical Research in D.C.
- The Debt Deal and Research Funding
- Carol Greider discusses funding prospects for the next generation of innovators
- Stoking the research engine
- $2.5M NIH "Pioneer" Award Goes to Johns Hopkins Pharmacologist
- Molecular pathways and networks
- Goal: A blood test for colon cancer
- Journal fever and the pressure to publish
- Diversified portfolios
- Of stipends and science
- Stemming shady science
- Calling all donors
- Money in the meantime
- Do team-based project grants provide the answer during a funding crisis?
- An acute need for more endowed chairs
- Lead Advisor: Alice Huang
Genes, Genomics and Bioinformatics (back to top)
- Mapping Genetic Changes Across Generations
- Genome detectives: New bioinformatics lab interprets genetic code
- Rare Form of Active 'Jumping Genes' Found In Mammals
- Computers "Taught" To ID Regulating Gene Sequences
- Johns Hopkins Scientists Find Genes Related to Body Mass
- "Synthetic" Chromosome Permits Rapid, On-Demand "Evolution" of Yeast
- Genetic Fishing Expedition Yields Surprising Catch Important to Mammals
- More "Functional" DNA in Genome than Previously Thought
- Dynamic DNA Segments Don't Stay Put
- Yeast Construction Zone
- Scientists Identify DNA That May Contribute to Each Person's Uniqueness
- Junk DNA May Not Be So Junky After All
- Keeping chromosomes intact
- Solving the structure of a protein that controls genes
- Protecting cells from damaged DNA
- Geography matters in the nucleus
- Scientists out a gene for gout
Hearing and Deafness (back to top)
- That ringing in your ears...
- Exploring the deep recesses of the inner ear
- Surviving Dance Club Music (Noise) With Hearing Intact
- The Beauty and Biology of the Inner Ear
- Now hear this
HIV (back to top)
- Seeing Through HIV's Disguises
- Researchers Show How Cells' DNA Repair Machinery Can Destroy Viruses
- Killing HIV by Luring It out of Hiding
- HIV And Breast Cancer May Share A Common Enemy: Nelfinavir
- New Studies Show Which Anti-HIV Drug Combinations Work Better Than Others
- Hide-and-Seek: Altered HIV Can't Evade Immune System
- Acne Drug Prevents HIV Breakout
- Treating HIV-induced brain problems
- How HIV escapes cells
- Rooting out reservoirs of HIV infection
Immune System (back to top)
- New Technique Catalogs Lymphoma-Linked Genetic Variations
- The Inflammasome: Possible Clue to a Host of Diseases
- Simple Fungus Reveals Clue To Immune System Protection
- Built-In Molecular Brakes Curb the Sniffles
- Leprosy medicine holds promise as therapy for autoimmune diseases
- Johns Hopkins Scientists Tie Cell Cycle “Clock” To Childhood Cancers
- There's a New 'Officer' in the Infection Control Army
- Shedding light on lymphomas
- Mechanisms behind immune cell activation
- New Driver of Transplant Rejection: Platelets
- Avi Kupfer's Talking Picture Show
Learning and Memory (back to top)
- Going Places: Rat Brain 'GPS' Maps Routes to Rewards
- Pavlov's Rats? Rodents Trained to Link Rewards to Visual Cues
- Study Refutes Accepted Model of Memory Formation
- Making Memories: How One Protein Does It
- Johns Hopkins Scientists Reveal Molecular Sculptor of Memories
- A Light on Life's Rhythms
- Johns Hopkins Scientists Reveal New Survival Mechanism for Neurons
- Blood Vessels: The Pied Piper for Growing Nerve Cells
- Scientists Reveal Nerve Cells' Navigation System
- Researchers Discover How to Erase Memory
- Genetic 'Parts' List Now Available For Key Part of The Mammalian Brain
- Brain's White Matter: More "Talkative" Than Once Thought
- The Hippocampus’ Remembrance of Things Past
- How nerve cells learn
- How the brain controls muscle movement
- Going through the motions
- Math that Powers Spam Filters Used to Understand how Brain Learns to Move Our Muscles
- To stay or to go
- How the brain remembers things for more than an hour or two
- For motor neurons: Mother may I?
- What emotional memories are made of
- How memories are stored in the brain
- How memories are formed
- Watching memories form in real time
- Reducing memory to a molecule: A researcher explores the molecular essence of memory
- This is your brain on fatty acids
- Adult Brain Cells Are Movers and Shakers
- Gene Linked To Severity of Autism's Social Dysfunction
- Johns Hopkins Researchers Create New Mouse Model of Autism
- "Lab on a Chip" Mimics Brain Chemistry
- "Epigenetic" Marks a Clue to Multiple Functions of the Brain
Liver Disease (back to top)
Model Organisms (back to top)
- How Bees Decide What To Be
- The Tube: Nature’s Go-to Geometry
- Why Many Cells are Better than One
- The Mouse Model: Less than Perfect, Still Invaluable
- Raising the Bar on Animal Care
Molecular Biology (back to top)
- Location, Location, Location: Membrane 'Residence' Gives Proteases Novel Abilities
- Folate Mystery Finally Solved
- Bacterial Cytoskeleton May Offer New Drug Target
- You Can't Keep A Good Cell Down
- Happy Accident Answers Cell Signal Controversy
- The Hop and Slide of DNA Repair
- Rearranging the Cell's Skeleton
- Hopkins Researchers Find New Genetic Switch that Allows Cells to Thrive in Low Oxygen
- Researchers Reshape Basic Understanding of Cell Division
- Positively Negative: Cellular Structure's "Enforcer" Role Discovered by Johns Hopkins Scientists
- Making proteins
- Cell machinery sniffs out gene damage by trying on DNA for size
- The complex choreography of protein translation
- Lost in Translation
- The Shape-Shifting Mechanics of Cells
- Argonautes: A Big Turn-Off For Proteins
- Antioxidant controls spinal cord development
- Dividing cells "feel" their way out of warp
- Researchers Uncover New Kink in Gene Control
- Scientist shines light on molecular signaling
- A Biophysicist Studies Promiscuity (Among Molecules)
- How cells communicate: Implications for a rare cognitive disorder
- Scientists Discover How a Tiny Protein Senses All the Communications in a Cell
Muscle Wasting Diseases (back to top)
- Pushing the Boundaries
- Protein Creates Paths For Growing Nerve Cells
- Hopkins Researchers Solve Key Part Of Old Mystery In Generating Muscle Mass
- How Muscle Develops: A Dance of Cellular Skeletons
- Muscle Science
- Macho Muscle Cells Force Their Way to Fusion
- Muscle "Fusion" Protein Found by Johns Hopkins Researchers
- Maintaining muscle mass
- "Mighty Mice" Made Mightier
- How the brain controls muscle movement
- Math that Powers Spam Filters Used to Understand how Brain Learns to Move Our Muscles
Treating Neurological Diseases (back to top)
- Fatheads: How Neurons Protect Themselves Against Excess Fat
- Researchers Discover New Clues about how Amyotrophic Lateral Sclerosis (ALS) Develops
- Molecular 'Two-Way Radio' Directs Nerve Cell Branching And Connectivity
- Protein Creates Paths For Growing Nerve Cells
- Research On Blood Vessel Proteins Holds Promise For Controlling 'Blood-Brain Barrier'
- Taking a chance: Assuming a larger role in drug discovery
- Fruit Flies Reveal Mechanism Behind ALS-Like Disease
- Neural Protective Protein Has Two Faces
- Neural Connections
- Johns Hopkins Scientists Reveal New Survival Mechanism for Neurons
- Engineering A Better Treatment For Parkinson's Disease
- Mysterious Cells May Play Role in ALS
- Anti-dandruff shampoo ingredient may control siezures
- Antipsychotic drugs: Why they cause weight gain
- Tiny protein-activator responsible for brain cell damage
- How cells communicate: Implications for a rare cognitive disorder
- One Step Closer To Closure: Key to Spinal Cord Defects
- Johns Hopkins Scientists Discover A Controller Of Brain Circuitry
- Killer Competition: Neurons Duke It Out for Survival
- Improving Recovery from Spinal Cord Injury
- Antioxidant Controls Spinal Cord Development
- Gene Linked To Severity of Autism's Social Dysfunction
- Johns Hopkins Researchers Create New Mouse Model of Autism
- Fruit Fly Discovery Generates Buzz About Brain-Damaging Disorder In Children
Pain (back to top)
- Ouch! Making Sense of Sensation
- Making cox-2 inhibitors safer
- A sixth sense and beyond
- Scientists Find a Source of Nonallergic Itch
Parasitic Diseases (back to top)
- Structure Discovered For Promising Tuberculosis Drug Target
- Folate Mystery Finally Solved
- Bacterial Cytoskeleton May Offer New Drug Target
- Is It A Rock, Or Is It Jell-O? Defining the Architecture of Rhomboid Enzymes
- Hopkins Team Finds New Way To Attack TB
- Hopkins Scientists Discover How Protein Trips Up Germs
- More of a reason to eat those vegetables
- Gutsy germs succumb to baby broccoli
- How Montezuma gets his revenge
- What drives the fatal form of malaria
- New lead on malaria treatment
Proteomics (back to top)
- Seeing Through HIV's Disguises
- The Inflammasome: Possible Clue to a Host of Diseases
- Akhilesh Pandey’s quest to pin down the entire human proteome
- Speeding "Fingertip" Discovery-Twenty Years of Protein Info in One Place
- Bringing up (the protein) baby
Smell and Taste (back to top)
- Blood Vessels 'Sniff' Gut Microbes To Regulate Blood Pressure
- The Nose Knows: Gene Therapy Restores Sense Of Smell In Mice
- How the Brain Smells
- The Sniffing Kidney
- What Accounts For Insect Taste?
- Scientists Discover How Chemical Repellants Trip Up Insects
- Regrowing nose nerves
Stem Cells (back to top)
- Hopkins Researchers Solve Key Part Of Old Mystery In Generating Muscle Mass
- Nanoscale Scaffolds and Stem Cells Show Promise in Cartilage Repair
- Discovery of ‘Master Molecule’ Could Improve Stem Cell Treatment for Heart Attacks
- Keeping Stem Cells From Changing Fates
- Scientists Reveal How Induced Pluripotent Stem Cells Differ From Embryonic Stem Cells
- Scientists Map Epigenetic Changes During Blood Cell Differentiation
- The Molecular Perspective on Stem Cells
- When good cells turn bad: Are stem cells a breeding ground for cancer?
- Regrowing nose nerves
- Making stem cells from developing sperm
- Induced Pluripotent Stem Cells: Not Yet the Perfect Alternative
- Stem Cells Battle for Space
Synthetic Biology (back to top)
- Microchoreography: Researchers use synthetic molecule to guide cellular “dance”
- Training Cells to Perform Boolean Functions? It's Logical
- Researchers Put Proteins Right Where They Want Them: Location Determines a Protein's Role
- Researchers Use Light To Move Molecules
- Johns Hopkins Researchers Mentor Two Undergrad Teams for iGEM Worldwide Synthetic Biology Competition
- "Synthetic" Chromosome Permits Rapid, On-Demand "Evolution" of Yeast
- Yeast Construction Zone
Telomeres and Telomerase (back to top)
- Carol Greider Shares 2009 Nobel Prize in Physiology or Medicine
- Stopping cancer by blocking telomerase
Technology (back to top)
- Digging Up Molecular Fossils on Mars
- Computers "Taught" To ID Regulating Gene Sequences
- The Science of Scientific Images
- Scientists on Images That Made a Difference in Their Lives
- Personalizing Medicine Through Processors and Petabytes
- Taking a chance: Assuming a larger role in drug discovery
- Training Cells to Perform Boolean Functions? It's Logical
- Building a better drug
- Techno Love-Hate
- A Robot that Helps Teach the Language of Surgery
- "Lab on a Chip" Mimics Brain Chemistry
- New Composite Material May Restore Damaged Soft Tissue
- Just Add Water and...Treat Brain Cancer
- Building Tissues From Scratch
- Seeking Collaborators In The Facebook Age
- Little green ions, or Honey, I Shrunk the Mass Spectrometer
- Medical School's Mass Spec Experts Aid Search for Life On Mars
- Need more resolution?
- Bringing up (the protein) baby
- More bang for your microarray buck
- Data dowsers
- Seeing is believing
- All the (microscopic) world's a stage
- RACking up tools
- Core facilities aim to serve while keeping in the black
- A prosthetic arm like no other
- Chemical found in medical devices impairs heart function
Touch and Skin Diseases (back to top)
- Itchy Wool Sweaters Explained
- Why Our Backs Can't Read Braille
- His And Hers: Male Hormones Control Differences In Mammary Gland Nerve Growth
- Natural Chemical Found in Broccoli Helps Combat Skin Blistering Disease
- Too Hot to Handle! Scientists Identify Heat Sensing Regulator
- Summer Heat Too Hot for You? What is Comfortable?
- Touching a Nerve
Translating Basic Research: From bench to bedside (back to top)
- Commercialization: No Longer a Dirty Word
- Reaping the fruits of research
- Getting the word on time: Tech transfer gives early feedback on inventions
- Smothering the fire of genius: Can some patent-holders stymie a field of emerging research?
- Keeping a lid on negativity: should only positive findings be reported?
Vision and Blindness (back to top)
- Shining a Light on Pupil Constriction
- A Light on Life's Rhythms
- Why Animals Don't Have Infrared Vision
- Role of Light Sensor In Temperature Sensation
- All Eyes on Retinal Degeneration
- Proper blood vessel growth in the eyes
- The cause of light blindness
- How eyes respond to light intensity
- Reducing retinal degeneration
- How color vision came to be
- Enhancing color vision
- A sixth sense and beyond
- Baiting the hook
- Sight gone, but not necessarily lost
- An 'eye catching' vision discovery
- Bright Lights, Not-So-Big Pupils
- The difference between eye cells
- Understanding Night Blindness and Calcium
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