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Joseph Michael Herman, MD

Herman, Joseph Michael, MD
Associate Professor of Radiation Oncology and Molecular Radiation Sciences
Associate Professor of Oncology
Associate Professor of Surgery
Director of the Pancreatic Multidisciplinary Clinic
Appointment Phone:
410-502-8000
Primary Location:
Johns Hopkins Sidney Kimmel Comprehensive Cancer Center
Expertise:
Anal Cancer, Bile Duct Cancer, Bladder Cancer, Brachytherapy, Cancer, Colorectal Cancer, Gastric Cancer, Gastrointestinal Cancers, Image-Guided Radiation Therapy, Liver Cancer, Oncology, Pancreatic Cancer, Radiation Oncology, Rectal Cancer, Stereotactic Body Radiation Therapy

Locations

Johns Hopkins Sidney Kimmel Comprehensive Cancer Center
401 N. Broadway
Baltimore, MD 21231
Phone: 410-502-3823
Appointment Phone: 410-502-8000
Fax: 410-502-1419
Location Map
Department / Division
  • Radiation Oncology and Molecular Radiation Sciences

Bio

Biography
Dr. Herman is the director of the pancreatic multi-disciplinary clinic and focuses on translational treatments for gastrointestinal malignancies. His research interests include innovative combinations of stereotactic radiation with immunotherapy and targeted agents for pancreatic and liver cancers. Other interests include outcomes reasearch and treatment related quality of life. He specializes in intraoperative radiation therapy for recurrent malignancies and endorectal brachtherapy for early stage rectal cancers.
Physician Title
Director of the Pancreatic Multidisciplinary Clinic
Awards and Honors
1994 Letter of Commendation, National Institutes of Health, Neurogenetics Section
1995 Graduate Merit Award, UMAB Master of Science in Preventive Medicine
1997 Awarded STRTP NIH grant to develop an IFA assay for HHV-8 and Kaposis Sarcoma
2001 Awarded Intern of the Month, University of Michigan Internal Medicine
2005 Chief Resident, Awarded RSNA Resident of the Year (University of Michigan)
2006 Awarded stipend to participate in the 2006 AACR/ASCO Workshop on Methods in Clinical Cancer Research
2008 AACR Career Development Award for Pancreatic Cancer Research, Cancer Vaccine
2008 Johns Hopkins Oncology Center Teaching Award
2008 Junior Faculty Award to present at SANTRO
2009 Selected Moderator Gastrointestinal Section ASTRO 2009 2010 Selected for Johns Hopkins Leadership Development Programs
Expertise
  • Anal Cancer
  • Bile Duct Cancer
  • Bladder Cancer
  • Brachytherapy
  • Cancer
  • Colorectal Cancer
  • Gastric Cancer
  • Gastrointestinal Cancers
  • Image-Guided Radiation Therapy
  • Liver Cancer
  • Oncology
  • Pancreatic Cancer
  • Radiation Oncology
  • Rectal Cancer
  • Stereotactic Body Radiation Therapy

Education and Experience

Training
  • University of Maryland Medical System (Baltimore MD)/ (2000)
Residencies
  • University of Michigan Health System (Ann Arbor MI)/ Radiation Oncology (2005)
Certifications
  • Radiation Oncology, American Board of Radiology (2006)

Centers/Institutes

Centers / Institutes
  • Pancreatic Cancer Multidisciplinary Center
  • Sidney Kimmel Comprehensive Cancer Center

Research

Research and Publications
Swartz MJ, Hughes MA, Frassica DA, Herman J, Yeo CJ, Riall TS, Lillemoe KD, Cameron JL, Donehower RC, Laheru DA, Hruban RH, Abrams RA. Adjuvant Concurrent Chemoradiation for Node-Positive Adenocarcinoma of the Duodenum. Arch Surg. 2007; 142(3):285-288.

Karikari CA, Roy I, Tryggestad E, Feldmann G, Pinilla C, Welsh K, Reed JC, Armour EP, Wong J, Herman J, Rakheja D, Maitra A. Targeting the Apoptotic Machinery in Pancreatic Cancers using Small Molecule Antagonists of the X-linked Inhibitor of Apoptosis Protein. Mol Cancer Ther. 2007; 6(3):957-966.

Lopez CA, Feng FF, Herman JM, Nyati M, Lawrence TS, Ljungman M. Phenylbutyrate Sensitize Human Glioblastoma Cells Lacking Wild Type p53 Function to Ionizing Radiation. Int J Rad Onc Biol Phys. 2007; 69(1):214-220.

Poggi MM, Suh WW, Saltz L, Konski AA, Mohiuddin M, Herman J, Johnstone PA. ACR Appropriateness Criteria on Treatment of Anal Cancer. J Am Coll Radiol. 2007; Jul;4(7):448-456.

Gleisner AL, Assumpcao L, Cameron JL, Wolfgang CL, Choti MA, Herman JM, Schulick RD, Pawlik TM. Is Resection of Periampullary or Pancreatic Adenocarcinoma with Synchronous Hepatic Metastasis Justified? Cancer. 2007; Dec 1;110(11):2484-2492.

Assumpcao L, Choti MA, Gleisner AL, Schulick RD, Swartz M, Herman J, Gearhart SL, Pawlik TM. Patterns of Recurrence following Liver Resection for Colorectal Metastases: Impact of Primary Rectal Tumor Site. Arch Surg. 2008; 143(8):743-749; discussion 749-750.

Suh WW, Johnstone PA, Herman J, Blackstock AW, Konski AA, Mohiuddin M, Poggi MM, Regine WF, Rich TA, Cosman BC, Saltz L. Expert Panel on Radiation Oncology-Rectal/Anal Cancer Panel: Resectable Rectal Cancer. Int J Radiat Oncol Biol Phys. 2008; Apr 1;70(5):1427-1430.

Slidell MB, Chang DC, Cameron JL, Wolfgang C, Herman JM, Schulick RD, Choti MA, Pawlik TM. Impact of Total Lymph Node Count and Lymph Node Ratio on Staging and Survival after Pancreatectomy for Pancreatic Adenocarcinoma: A Large, Population-Based Analysis. Ann Surg Oncol. 2008; Jan;15(1):165-174.

Herman JM, Swartz MJ, Hsu CC, Winter J, Pawlik TM, Sugar E, Robinson R, Laheru D, Jaffee E, Hruban R, Campbell K, Wolfgang C, Asrari F, Donehower R, Hidalgo M, Diaz Jr., L, Yeo C, Cameron J, Schulick R, Abrams R. Analysis of Adjuvant Chemotherapy and Radiation after Pancreaticoduodenectomy for Ductal Adenocarcinoma of the Pancreas: Results of a Large Prospectively Collected Database. J Clin Oncol. 2008; 26(21):3503-3510.

Herman J, Pierce LJ, Sandler HM, Griffith KA, Jabbari S, Hiniker SM, Johnson TM. Radiotherapy Using a Water Bath in the Treatment of Bowens Disease of the Digit. Radiother Oncol. 2008; 88(3):398-402.

Pawlik TM, Laheru D, Hruban RH, Coleman J, Wolfgang CL, Campbell K, Ali S, Fishman EK, Schulick RD, Herman JM. Evaluating the Impact of a Single-Day Multidisciplinary Clinic on the Management of Pancreatic Cancer. Ann Surg Oncol. 2008; Aug;15(8):2081-2088. Epub 2008 May 7.

Reddy S, Edil B, Cameron J, Pawlik TM, Herman JM, Gilson M, Campbell K, Schulick R, Ahuja N, Wolfgang C. Pancreatic Resection of Isolated Metastases from Nonpancreatic Primary Cancers. Ann Surg Oncol. 2008;15(11):3199-3206.

Assumpcao L, Cameron JL, Wolfgang CL, Edil B, Choti MA, Herman JM, Geschwind JF, Hong K, Georgiades C, Schulick RD, Pawlik TM. Incidence and Management of Chyle Leaks following Pancreatic Resection: A High Volume Single-Center Institutional Experience. J Gastrointest Surg. 2008; 12(11):1915-1923.

Herzer KR, Rodriguez-Paz JM, Doyle PA, Flint PW, Feller-Kopman DJ, Herman J, Bristow RE, Cover R, Pronovost PJ, Mark LJ. A Practical Framework for Patient Care Teams to Prospectively Identify and Mitigate Clinical Hazards. Jt Comm J Qual Patient Saf. 2008; 35(2):72-81.

Hong K, McBride JD, Georgiades CS, Reyes DK, Herman JM, Kamel IR, Geschwind J. Salvage Therapy for Liver-Dominant Colorectal Metastatic Adenocarcinoma: Comparison between Transcatheter Arterial Chemoembolization versus Yttrium-90 Radioembolization. J Vasc Interv Radiol. 2009; 20:360-367.

Iacobuzio-Donahue CA, Fu B, Yachida S, Luo M, Abe H, Henderson CM, Vilardell F, Wang Z, Keller JW, Banerjee P, Herman JM, Cameron JL, Yeo CJ, Halushka MK, Eshleman JR, Raben R, Klein AP, Hruban RH, Hidalgo M, Laheru D. DPC4 Gene Status of the Primary Carcinoma Correlates with Patterns of Failure in Patients with Pancreatic Cancer. J Clin Oncol. 2009; 27(11):1806-1813. Epub 2009 March 9.

Nathan H, Wolfgang CL, Edil BH, Choti MA, Herman JM, Schulick RD, Cameron JL, Pawlik TM. Peri-Operative Mortality and Long-term Survival after Total Pancreatectomy for Pancreatic Adenocarcinoma: A Population-Based Perspective. J Surg Oncol. 2009; 99(2):87-92.

Asiyanbola B, Gleisner A, Herman JM, Choti MA, Wolfgang CL, Swartz M, Edil BH, Schulick RD, Cameron JL, Pawlik TM. Determining Pattern of Recurrence Following Pancreaticoduodenectomy and Adjuvant 5-Flurouracil-Based Chemoradiation Therapy: Effect of Number of Metastatic Lymph Nodes and Lymph Node Ratio. J Gastrointest Surg. 2009; 13(4):752-759.

Rodriguez-Paz JM, Mark LJ, Herzer KR, Michelson JD, Grogan KL, Herman J, Hunt D, Wardlow L, Armour EP, Pronovost PJ. A Novel Process for Introducing New Intraoperative Program: A Multidisciplinary Paradigm for Mitigating Hazards and Improving Patient Safety. Anesth Analg. 2009; 108(1):202-210.

Blackford A, Serrano OK, Wolfgang C, Parmigiani G, Jones S, Zhang X, Parsons DW, Lin JC-H, Leary RJ, Eshleman JR, Goggins M, Jaffee EM, Iacobuzio-Donahue CA, Maitra A, Cameron JL, Olino K, Schulick R, Winter J, Herman JM, Laheru D, Vogelstein B, Kinzler KW, Velculescu VE, Hruban RH. SMAD4 Gene Mutations Are Associated with Poor Prognosis in Pancreatic Cancer. Clin Cancer Res. 2009; 15(14):4674-4679.

Wang L, Brune KA, Visvanathan K, Laheru D, Herman J, Wolfgang C, Schulick R, Cameron J, Goggins M, Hruban RH, Klein AP. Elevated Mortality from Breast and Ovarian Cancers in the Relatives of Patients with Familial Pancreatic Cancer. Cancer Epidemiol Biomarkers Prev. 2009; Nov;18(11):2829-2834. Epub 2009 Oct 20.

Zhou J, Hsu CC, Winter JM, Pawlik TM, Laheru D, Hughes MA, Donehower R, Wolfgang C, Akbar U, Schulick R, Cameron J, Herman JM. Adjuvant Chemoradiation versus Surgery Alone for Adenocarcinoma of the Ampulla of Vater. Radiother Oncol. 2009; 92(2):244-248.

Nathan H, Raut CP, Thornton K, Herman JM, Ahuja N, Schulick RD, Choti MA, Pawlik TM. Predictors of Survival after Resection of Retroperitoneal Sarcoma: A Population-based Analysis and Critical Appraisal of the AJCC Staging System. Ann Surg. 2009; 250(6):970-976.

Hristov B, Reddy S, Lin SH, Cameron JL, Pawlik TM, Hruban RH, Swartz, MJ, Edil BH, Kemp C, Wolfgang CL, Herman JM. Outcomes of Adjuvant Chemoradiation after Pancreaticoduodenectomy with Mesenterico-Portal Vein Resection for Adenocarcinoma of the Pancreas. Int J Radiat Oncol Biol Phys. 2010; Jan 1;76(1):176-180. Epub 2009 Apr 24.

Voong R, Davison J, Pawlik TM, Uy MO, Hsu CC, Winter J, Hruban RH, Laheru D, Rudra S, Swartz M, Nathan H, Edil B, Schulick R, Cameron J, Wolfgang CL, Herman JM. Resected Pancreatic Adenosquamous Carcinoma: Clinicopathologic Review and Evaluation of Adjuvant Chemotherapy and Radiation in 38 Patients. Hum Pathol. 2010; Jan;41(1):113-122. Epub 2009 Oct 3.

Goldstein S, Ford E, Duhon M, McNutt T, Wong J, Herman JM. Use of Respiratory-Correlated 4-D CT Imaging to Determine Acceptable Treatment Margins for Locally Advanced Pancreatic Adenocarcinoma. Int J Radiat Oncol Biol Phys. 2010; Feb 1;76(2):597-602. Epub 2009 Oct 14.

Swartz MJ, Hsu CC, Pawlik TM, Winter J, Hruban RH, Guler M, Schulick RD, Cameron JL, Laheru DA, Wolfgang CL, Herman JM. Adjuvant Chemoradiotherapy after Pancreatic Resection for Invasive Carcinoma Associated with Intraductal Papillary Mucinous Neoplasm of the Pancreas. Int J Radiat Oncol Biol Phys. 2010; Mar 1;76(3):839-844. Epub 2009 Aug 3.

Hsu CC, Herman JM, Corsini MM, Winter JM, Callister MD, Haddock MG, Cameron JL, Pawlik TM, Schulick RD, Laheru DA, Farnell MB, Swartz MJ, Gunderson LL, Miller RC. Adjuvant Chemoradiation for Pancreatic Adenocarcinoma: The Johns Hopkins Hospital Mayo Clinic Collaborative Study. Ann Surg Oncol. 2010; Apr;17(4):981-990. Epub 2010 Jan 20.

Winter JM, Cameron JL, Olino K, Herman JM, Hruban RH, Wolfgang CL, Eckhauser F, Edil B, Choti MA, Schulick RD, Pawlik TM. Clinicopathologic Analysis of Ampullary Tumors in 450 Patients: Implications for Surgical Strategy and Long-Term Prognosis. J Gastrointest Surg. 2010; Feb;14(2):379-387.

Shaha M, Pandian V, Choti MA, Stotsky E, Herman JM, Khan Y, Libonati C, Pawlik TM, Schulick RD, Belcher AE. Transitoriness in Cancer Patients: A Cross-Sectional Survey of Lung and Gastrointestinal Cancer Patients. Support Care Cancer. Epub 2010 Feb 21.

Scudiere JR, Shi C, Hruban RH, Herman JM, Fishman EK, Schulick RD, Wolfgang CL, Makary MA, Thornton K, Montgomery E, Horton KM. Sclerosing Mesenteritis Involving the Pancreas: A Mimicker of Pancreatic Cancer. Am J Surg Pathol. 2010; Apr;34(4):447-453.

De Jong MC, Farnell MB, Sclabas G, Cunningham SC, Cameron JL, Geschwind J-F, Wolfgang CL, Herman JM, Edil BH, Choti MA, Schulick RD, Nagorney DM, Pawlik TM. Liver-Directed Therapy for Hepatic Metastases in Patients Undergoing Pancreaticoduodenectomy: A Dual-Center Analysis. Ann Surg. 2010 Jul;252(1):142-8.

Tsai S, Choti MA, Cameron JL, Assumpcao L, Gleisner AL, Herman JM, Eckhauser F, Edil B, Schulick RD, Wolfgang C, Pawlik TM. Impact of Obesity on Peri-operative Outcomes and Survival Following Pancreaticoduodenectomy for Pancreatic Cancer: A Large Single Institution Study. J Gastrointest Surg. 2010 Jul;14(7):1143-50. Epub 2010 Apr 30.

Redmond KJ, Wolfgang CL, Sugar EA, Ahn J, Nathan H, Laheru D, Edil BH, Choti MA, Pawlik TM, Hruban RH, Cameron JL, Herman JM. Adjuvant Chemoradiation Therapy for Adenocarcinoma of the Distal Pancreas. Ann Surg Oncol. 2010 Aug 3.

Blackstock W, Russo SR, Konski AA, Suh WW, Cosman BC, Herman JM, Mohiuddin M, Poggi MM, Regine WF, Saltz L, Small W, Zook J. Local Excision in Early Stage Rectal Cancer. Curr Probl Cancer. 2010 May-Jun;34(3):193-200.

Herman J, Messersmith W, Konski AA, Suh WW, Blackstock W, Cosman B, Mohiuddin M, Poggi MM, Regine WF, Saltz L, Small W, Zook J. ACR Appropriateness Criteria. Rectal Cancer Metastatic Disease at Presentation. Curr Probl Cancer. 2010 May-Jun;34(3):201-10.

De Jong MC, Tsai S, Cameron JL, Wolfgang CL, Hirose K, Van Vledder MG, Eckhauser F, Herman JM, Edil BH, Choti MA, Schulick RD, Pawlik TM. Safety and Efficacy of Curative Intent Surgery for Peri-Ampullary Liver Metastasis. J Surg Oncol. 2010 Sep 1;102(3):256-63.

Horowitz DP, Hsu CC, Wang J, Makary MA, Winter JM, Robinson R, Schulick RD, Cameron JL, Pawlik TM, Herman JM. Adjuvant Chemoradiation Therapy After Pancreaticoduodenectomy in Elderly Patients with Pancreatic Adenocarcinoma. Int J Radiat Oncol Biol Phys. 2010 Jul 17. [Epub ahead of print]

Ma WW, Herman JM, Laheru D, Messersmith W, Jimeno A, Rudek M, Khan Y, Howard A, Schulick R, Donehower R, Hidalgo M. A Phase I Tolerability and Pharmacokinetic Study of Adjuvant Erlotinib (E) and Capecitabine (Cap) with Concurrent Radiation (RT) in Resected Pancreatic Cancer (PanCa). Transl Oncol. 2010 Dec 1;3(6):373-9

Mayo SC, Shore AD, Nathan H, Edil B, Wolfgang C, Hirose K, Herman J, Schulick RD, Choti MA, Pawlik TM. National Trends in the Management and Survival of Surgically Managed Gallbladder Adenocarcinoma Over 15 years: A Population-Based Analysis. J Gastrointest Surg. 2010 Oct;14(10):1578-91. Epub 2010 Sep 8.

Lutz E, Yeo C, Lillemoe K, Biedrzycki B, Kobrin B, Herman J, Sugar E, Piantadosi, S, Cameron J, Solt S, Onners B, Tartakovsky I, Choi M, Sharma R, Illei PB, Hruban R, Abrams R, Le D, Jaffee E, Laheru D. A Lethally Irradiated Allogeneic Granulocyte-Macrophage Colony Stimulating Factor-Secreting Tumor Vaccine for Pancreatic Adenocarcinoma: A Phase II Trial of Safety, Efficacy, and Immune Activation. Annals Surg Onc. 2010 Dec 17. [Epub ahead of print].

Research Interests
  • Multidisciplinary cancer care
  • Vaccine Therapy
  • Pancreas Cancer
  • Quality of Life and Outcomes
  • Endorectal and Intraoperative Brachytherapy
  • Liver Cancer
  • Stereotactic Radiation Therapy
  • Anal Cancer
  • Rectal Cancer

More Info

Languages
  • English
Memberships
American Society of Clinical Oncology (ASCO)
American Society for Therapeutic Radiology and Oncology (ASTRO)
American Association for Cancer Research (AACR)
American College of Radiology (ACR)
Clinical Trials
  • Stereotactic Radiation
  • Brachytherapy
  • Vaccine Therapy
  • Rectal Cancer
  • Pancreas Cancer
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