THE FDA HAS ISSUED A WARNING ABOUT THE STATIN MEDICATION CALLED SIMVASTATIN, ELIZABETH TRACEY REPORTS
Simvastatin is one of the class of medications know as ‘statins,’ used to lower LDL cholesterol and reduce one’s risk for cardiovascular disease, but the FDA says use of the 80mg dose should be sharply curtailed. Edward Kasper, chief of clinical cardiology at Johns Hopkins, explains.
KASPER: Statins are the most effective drug that we have to lower cholesterol . Using statins to lower cholesterol is associated with an improvement in what we call hard clinical outcomes: death, and heart attack and stroke. And there are a whole variety of statins. These drugs all have a different variety of means of elimination. Simvastatin, particularly the 80 mg dose, appears to be associated with a really troublesome risk of muscle breakdown and that’s the reason the FDA removed it. :28
Kasper says there are many alternatives to simvastatin so reducing or eliminating use of this particular drug shouldn’t present a hardship to anyone. At Johns Hopkins, I’m Elizabeth Tracey.